The Dual Role of miR-186 in Cancers: Oncomir Battling With Tumor Suppressor miRNA

scientific article published on 05 March 2020

The Dual Role of miR-186 in Cancers: Oncomir Battling With Tumor Suppressor miRNA is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3389/FONC.2020.00233
P932PMC publication ID7066114
P698PubMed publication ID32195180

P2093author name stringLi Guan
Qing Tian
Ying Xiang
Shuai-Shuai Niu
P2860cites workNotch signaling induces cell cycle arrest in small cell lung cancer cellsQ24291129
New microRNAs from mouse and humanQ24540176
The Hippo Signaling Pathway in Development and CancerQ24603986
Global cancer statistics, 2012Q27860501
A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer cellsQ28573536
Target mRNA abundance dilutes microRNA and siRNA activityQ28914780
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.Q30539598
HMGN5/NSBP1: a new member of the HMGN protein family that affects chromatin structure and functionQ33637905
EMT and MET: necessary or permissive for metastasis?Q33869775
Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancerQ33894047
Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanismsQ34146004
MicroRNA-494 targeting both proapoptotic and antiapoptotic proteins protects against ischemia/reperfusion-induced cardiac injuryQ34207303
TWIST and ovarian cancer stem cells: implications for chemoresistance and metastasisQ34365639
CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.Q34487797
Polymorphisms in microRNA targets: a gold mine for molecular epidemiologyQ34778438
MicroRNAs miR-186 and miR-150 down-regulate expression of the pro-apoptotic purinergic P2X7 receptor by activation of instability sites at the 3'-untranslated region of the gene that decrease steady-state levels of the transcriptQ34804590
Genetic polymorphisms in miRNAs targeting the estrogen receptor and their effect on breast cancer risk.Q34879842
miR-186 and 326 predict the prognosis of pancreatic ductal adenocarcinoma and affect the proliferation and migration of cancer cellsQ35151728
Increased Expression of GOLPH3 is Associated with the Proliferation of Prostate CancerQ35349161
Expression and promotor hypermethylation of miR-34a in the various histological subtypes of ovarian cancer.Q35924210
Intron Retention and TE Exonization Events in ZRANB2.Q36063492
Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancerQ36338901
MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1Q36341067
miR-186 inhibits cell proliferation of prostate cancer by targeting GOLPH3Q37215525
miR-186 affects the proliferation, invasion and migration of human gastric cancer by inhibition of Twist1.Q37694872
Milk and dairy consumption and risk of bladder cancer: a meta-analysisQ37964263
Regulation of miR-23b expression and its dual role on ROS production and tumour development.Q38206343
A catalog of polymorphisms falling in microRNA-binding regions of cancer genesQ38297295
PTEN and PI3K/AKT in non-small-cell lung cancer.Q38629644
miRNA-186 inhibits prostate cancer cell proliferation and tumor growth by targeting YY1 and CDK6.Q38701099
MicroRNA-186-5p overexpression modulates colon cancer growth by repressing the expression of the FAM134B tumour inhibitor.Q38702143
Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers.Q38708075
MiR-186 Inhibited Migration of NSCLC via Targeting cdc42 and Effecting EMT ProcessQ38711597
TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axisQ38711940
The long noncoding RNA PVT1 functions as a competing endogenous RNA by sponging miR-186 in gastric cancerQ38719489
PVT1 affects growth of glioma microvascular endothelial cells by negatively regulating miR-186.Q38738395
miR-186 regulates chemo-sensitivity to paclitaxel via targeting MAPT in non-small cell lung cancer (NSCLC).Q38740398
MicroRNA-186 suppresses cell proliferation and metastasis through targeting MAP3K2 in non-small cell lung cancerQ38753282
microRNA-186 Suppresses Cell Proliferation and Metastasis Through Targeting Sentrin Specific Protease 1 in Renal Cell CarcinomaQ38760455
microRNA-186 inhibits cell proliferation and induces apoptosis in human esophageal squamous cell carcinoma by targeting SKP2.Q38819565
miR-186 downregulates protein phosphatase PPM1B in bladder cancer and mediates G1-S phase transitionQ38825749
miR-186 regulation of Twist1 and ovarian cancer sensitivity to cisplatinQ38888166
miR-186 downregulation correlates with poor survival in lung adenocarcinoma, where it interferes with cell-cycle regulation.Q38928705
miR-124 inhibits growth and invasion of gastric cancer by targeting ROCK1.Q38961961
MiR-186 targets ROCK1 to suppress the growth and metastasis of NSCLC cellsQ38988557
miR-186 inhibits muscle cell differentiation through myogenin regulationQ39037772
NR5A2 discovering compounds that block tumor growth in PDAC.Q39264548
MicroRNA-186 targets Yes-associated protein 1 to inhibit Hippo signaling and tumorigenesis in hepatocellular carcinomaQ39654967
MiR-186 suppresses the growth and metastasis of bladder cancer by targeting NSBP1.Q40625331
MicroRNA-186 regulates the invasion and metastasis of bladder cancer via vascular endothelial growth factor C.Q41665099
MicroRNA-186 affects the proliferation of tumor cells via yes-associated protein 1 in the occurrence and development of pancreatic cancerQ41672310
MicroRNA-186 suppresses lung cancer progression by targeting SIRT6.Q47361771
The Dual Regulatory Role of MiR-181a in Breast CancerQ47412689
The long noncoding RNA HULC promotes liver cancer by increasing the expression of the HMGA2 oncogene via sequestration of the microRNA-186.Q48002616
Suppression of Disheveled-Axin Domain Containing 1 (DIXDC1) by MicroRNA-186 Inhibits the Proliferation and Invasion of Retinoblastoma Cells.Q48372498
Long noncoding RNA PVT1 promotes EMT via mediating microRNA-186 targeting of Twist1 in prostate cancerQ49923086
Arresting of miR-186 and releasing of H19 by DDX43 facilitate tumorigenesis and CML progressionQ49957676
MiR-186 inhibits proliferation, migration, and invasion of non-small cell lung cancer cells by downregulating Yin Yang 1.Q50071627
MiR-186-5p upregulation inhibits proliferation, metastasis and epithelial-to-mesenchymal transition of colorectal cancer cell by targeting ZEB1.Q50080442
MicroRNA-186 serves as a tumor suppressor in oral squamous cell carcinoma by negatively regulating the protein tyrosine phosphatase SHP2 expressionQ50174418
Long non-coding RNA PVT1 serves as a competing endogenous RNA for miR-186-5p to promote the tumorigenesis and metastasis of hepatocellular carcinoma.Q50919252
LncRNA HCP5 promotes follicular thyroid carcinoma progression via miRNAs sponge.Q52363986
Micro-RNA-186-5p inhibition attenuates proliferation, anchorage independent growth and invasion in metastatic prostate cancer cells.Q52719567
The function role of miR-181a in chemosensitivity to adriamycin by targeting Bcl-2 in low-invasive breast cancer cells.Q53245125
An interplay of miRNA abundance and target site architecture determines miRNA activity and specificity.Q55374415
Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells.Q55411157
miR-186 promotes tumor growth in cutaneous squamous cell carcinoma by inhibiting apoptotic protease activating factor-1Q57787025
miR-186 reverses cisplatin resistance and inhibits the formation of the glioblastoma-initiating cell phenotype by degrading Yin Yang 1 in glioblastomaQ58597095
TBL1XR1 promotes migration and invasion in osteosarcoma cells and is negatively regulated by miR-186-5pQ60921924
A Systematic Review of miR-29 in CancerQ61811185
HOXD-AS1 promotes the epithelial to mesenchymal transition of ovarian cancer cells by regulating miR-186-5p and PIK3R3Q64079815
MicroRNA-186 targets SKP2 to induce p27-mediated pituitary tumor cell cycle deregulation and modulate cell proliferationQ64094803
MicroRNA-186 promotes cell proliferation and inhibits cell apoptosis in cutaneous squamous cell carcinoma by targeting RETREG1Q64233448
miR-186 inhibits cell proliferation in multiple myeloma by repressing Jagged1Q86931825
Dual Functional MicroRNA-186-5p Targets both FGF2 and RelA to Suppress Tumorigenesis of Glioblastoma MultiformeQ89305390
Overview upon miR-21 in lung cancer: focus on NSCLCQ90376926
miR-186 inhibits proliferation, migration, and epithelial-mesenchymal transition in breast cancer cells by targeting Twist1Q90534527
LncRNA SNHG16 Promotes Hepatocellular Carcinoma Proliferation, Migration and Invasion by Regulating miR-186 ExpressionQ91783143
miR-186 Suppresses the Progression of Cholangiocarcinoma Cells Through Inhibition of Twist1Q91894241
miR-186 modulates hepatocellular carcinoma cell proliferation and mobility via targeting MCRS1-mediated Wnt/β-catenin signalingQ92368136
miR-186-5p Functions as a Tumor Suppressor in Human Osteosarcoma by Targeting FOXK1Q92527980
Lycorine inhibited the cell growth of non-small cell lung cancer by modulating the miR-186/CDK1 axisQ92605329
EGFR, but not COX-2, protein in resected pancreatic ductal adenocarcinoma is associated with poor survivalQ92669175
Long Intergenic Non-Protein Coding RNA 665 Regulates Viability, Apoptosis, and Autophagy via the MiR-186-5p/MAP4K3 Axis in Hepatocellular CarcinomaQ92748612
CircRNA circPDSS1 promotes the gastric cancer progression by sponging miR-186-5p and modulating NEK2Q92995882
miR-186-5p promotes cell growth, migration and invasion of lung adenocarcinoma by targeting PTENQ93075512
Overexpression of microRNA-186 inhibits angiogenesis in retinoblastoma via the Hedgehog signaling pathway by targeting ATAD2Q93145597
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)233
P577publication date2020-03-05
P1433published inFrontiers in OncologyQ26839986
P1476titleThe Dual Role of miR-186 in Cancers: Oncomir Battling With Tumor Suppressor miRNA
P478volume10

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