Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine

scientific article published on 17 December 2018

Activity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1073/PNAS.1814709116
P932PMC publication ID6320534
P698PubMed publication ID30559184

P2093author name stringKenichi Fukumoto
Manoela V Fogaça
Ronald S Duman
Xiao-Yuan Li
Taro Kato
Rong-Jian Liu
Catharine Duman
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Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal culturesQ47388230
Common Neurotransmission Recruited in (R,S)-Ketamine and (2R,6R)-Hydroxynorketamine-Induced Sustained Antidepressant-like Effects.Q47570724
Lack of Antidepressant Effects of (2R,6R)-Hydroxynorketamine in a Rat Learned Helplessness Model: Comparison with (R)-KetamineQ47572680
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Activity-Dependent Brain-Derived Neurotrophic Factor Release Is Required for the Rapid Antidepressant Actions of ScopolamineQ47814036
(R)-Ketamine Shows Greater Potency and Longer Lasting Antidepressant Effects Than Its Metabolite (2R,6R)-Hydroxynorketamine.Q47822871
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GLYX-13 Produces Rapid Antidepressant Responses with Key Synaptic and Behavioral Effects Distinct from Ketamine.Q48472517
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Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cellsQ48733614
What Are the Causes for Discrepancies of Antidepressant Actions of (2R,6R)-Hydroxynorketamine?Q50155957
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P433issue1
P1104number of pages6
P304page(s)297-302
P577publication date2018-12-17
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleActivity-dependent brain-derived neurotrophic factor signaling is required for the antidepressant actions of (2R,6R)-hydroxynorketamine
P478volume116

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