Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

scientific article published on 23 March 2020

Neuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1242/BIO.049684
P698PubMed publication ID32205310

P50authorTamsin J. SamuelsQ63413977
Tzumin LeeQ64920902
David Ish-HorowiczQ88394222
Francesca RobertsonQ90603370
Jeffrey Y LeeQ90603375
Ilan DavisQ37388140
P2093author name stringAino I Järvelin
Lu Yang
Yoav Arava
Ching-Po Yang
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Prospero acts as a binary switch between self-renewal and differentiation in Drosophila neural stem cellsQ34586479
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The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in DrosophilaQ52537055
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FACS purification and transcriptome analysis of drosophila neural stem cells reveals a role for Klumpfuss in self-renewalQ37308487
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Temporal fate specification and neural progenitor competence during developmentQ38176634
Prospero-related homeobox 1 (Prox1) at the crossroads of diverse pathways during adult neural fate specificationQ38352458
Alternative polyadenylation coupled to transcription initiation: Insights from ELAV-mediated 3' UTR extensionQ38544367
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Steroid hormone induction of temporal gene expression in Drosophila brain neuroblasts generates neuronal and glial diversity.Q41837501
ELAV links paused Pol II to alternative polyadenylation in the Drosophila nervous system.Q42121025
Biochemical analysis of ++Prospero protein during asymmetric cell division: cortical Prospero is highly phosphorylated relative to nuclear ProsperoQ42466319
Stem Cell-Intrinsic, Seven-up-Triggered Temporal Factor Gradients Diversify Intermediate Neural ProgenitorsQ42776356
Transient nuclear Prospero induces neural progenitor quiescence.Q42965733
Making Drosophila lineage-restricted drivers via patterned recombination in neuroblastsQ44994515
Asymmetric segregation of Numb and Prospero during cell divisionQ46547833
SYNCRIP-dependent Nox2 mRNA destabilization impairs ROS formation in M2-polarized macrophagesQ46892219
Opposing intrinsic temporal gradients guide neural stem cell production of varied neuronal fatesQ46921548
Dcas is required for importin-alpha3 nuclear export and mechano-sensory organ cell fate specification in DrosophilaQ47070344
Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells.Q47071360
prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in DrosophilaQ47071678
Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewalQ47071774
Drosophila neuroblasts sequentially express transcription factors which specify the temporal identity of their neuronal progenyQ47072696
The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.Q47072815
Imp and Syp RNA-binding proteins govern decommissioning of Drosophila neural stem cellsQ47139889
Meta-analysis of 2,104 trios provides support for 10 new genes for intellectual disabilityQ48133294
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P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesDESeq2Q113018293
P577publication date2020-03-23
P1433published inBiology OpenQ27724268
P1476titleNeuronal upregulation of Prospero protein is driven by alternative mRNA polyadenylation and Syncrip-mediated mRNA stabilisation

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Q95315586CytoCensus, mapping cell identity and division in tissues and organs using machine learningcites workP2860

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