Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma

scientific article published on 09 October 2019

Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0223639
P932PMC publication ID6785123
P698PubMed publication ID31596908

P50authorAurora S BlucherQ89111566
Nathaniel EvansQ90611161
Ted LaderasQ56991718
P2093author name stringJeffrey W Tyner
Shannon K McWeeney
Molly Kulesz-Martin
Ashley Anderson
Sophia Jeng
Gabrielle Choonoo
Christina Zheng
James Jacobs
Benjamin Cordier
Mitzi Boardman
Myles Vigoda
Samuel Higgins
Steven Chamberlin
P2860cites workOral cancer in Fanconi anemia: Review of 121 casesQ88344657
Human papillomavirus and the landscape of secondary genetic alterations in oral cancersQ90622386
Loss of Function of Canonical Notch Signaling Drives Head and Neck CarcinogenesisQ90823594
Use of nonsteroidal anti-inflammatory drugs predicts improved patient survival for PIK3CA-altered head and neck cancerQ91228785
Visualization of drug target interactions in the contexts of pathways and networks with ReactomeFIVizQ92355875
Cetuximab-Containing Combinations in Locally Advanced and Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaQ92527773
Evidence-Based Precision Oncology with the Cancer Targetome.Q47893147
Genomic analysis of head and neck cancer cases from two high incidence regions.Q48149825
Crosstalk signaling between HER3 and HPV16 E6 and E7 mediates resistance to PI3K inhibitors in head and neck cancerQ50027355
Immunotherapy for Head and Neck Squamous Cell CarcinomaQ53704789
The promise of immunotherapy in head and neck squamous cell carcinoma: combinatorial immunotherapy approaches.Q54980315
Alterations in Cellular Iron Metabolism Provide More Therapeutic Opportunities for Cancer.Q55497286
Safety and Efficacy of Durvalumab With or Without Tremelimumab in Patients With PD-L1-Low/Negative Recurrent or Metastatic HNSCC: The Phase 2 CONDOR Randomized Clinical TrialQ58082830
Multiple Routes to Oncogenesis Are Promoted by the Human Papillomavirus-Host Protein NetworkQ59352781
Iron as a Central Player and Promising Target in Cancer ProgressionQ61796322
A study of TRAIL receptors in squamous cell carcinoma of the head and neckQ81752788
A poor prognosis subtype of HNSCC is consistently observed across methylome, transcriptome, and miRNome analysisQ86936493
The NOTCH Pathway in Head and Neck Squamous Cell CarcinomaQ87907785
Cytoscape: a software environment for integrated models of biomolecular interaction networksQ24515682
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrinQ24670040
Toward a Shared Vision for Cancer Genomic DataQ26966456
Squamous cell carcinomas of the head and neck in Fanconi anemia: risk, prevention, therapy, and the need for guidelinesQ27686904
Frequent mutation of the PI3K pathway in head and neck cancer defines predictive biomarkersQ27852227
Comprehensive genomic characterization of head and neck squamous cell carcinomasQ28256121
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortalQ28288215
Ten years of pathway analysis: current approaches and outstanding challengesQ29615564
ReactomeFIViz: a Cytoscape app for pathway and network-based data analysisQ30859718
Evidence for a causal association between human papillomavirus and a subset of head and neck cancersQ33180284
Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell carcinomaQ33566622
Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p lossQ34098286
A lethal combination for cancer cells: synthetic lethality screenings for drug discoveryQ34132195
Characterization of HPV and host genome interactions in primary head and neck cancersQ34442327
Distinct risk factor profiles for human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck cancersQ34760882
Emerging landscape of oncogenic signatures across human cancersQ35058708
Molecular introduction to head and neck cancer (HNSCC) carcinogenesis.Q35893787
Fanconi anemia: young patients at high risk for squamous cell carcinomaQ35933293
Quality of life research in head and neck cancer: a review of the current state of the scienceQ36780354
The Ensembl Variant Effect PredictorQ36970975
TRAIL induces apoptosis in oral squamous carcinoma cells--a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5.Q37016549
Identifying the risk factors for late-stage head and neck cancerQ37024527
A landscape of pharmacogenomic interactions in cancer.Q37140236
Applying synthetic lethality for the selective targeting of cancer.Q38263612
Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies.Q38636162
Combination Cancer Therapy Can Confer Benefit via Patient-to-Patient Variability without Drug Additivity or SynergyQ47303076
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesCytoscapeQ3699942
P433issue10
P921main subjecthead and neck squamous cell carcinomaQ18348812
P304page(s)e0223639
P577publication date2019-10-09
P1433published inPLOS OneQ564954
P1476titleIlluminating biological pathways for drug targeting in head and neck squamous cell carcinoma
P478volume14

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