Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis

scientific article published on 16 October 2018

Neurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/ACN3.638
P932PMC publication ID6292183
P698PubMed publication ID30564615

P50authorChristian BarroQ60690467
Tanuja ChitnisQ30353265
Rohit BakshiQ56515975
P2093author name stringHarald Kropshofer
Howard L Weiner
David Leppert
Ludwig Kappos
Jens Kuhle
Anu Paul
Bonnie I Glanz
Brian C Healy
Davorka Tomic
Pia Kivisakk
Zuzanna Michalak
Camilo Diaz-Cruz
Mattia Rosso
Shrishti Saxena
Cindy Gonzalez
Neda Sattarnezhad
Dieter Häring
Isabelle V Pierre
P2860cites workFatigue is intrinsic to multiple sclerosis (MS) and is the most commonly reported symptom of the diseaseQ80090456
Neurofilament light as a prognostic marker in multiple sclerosisQ82566866
Neurofilament levels as biomarkers in asymptomatic and symptomatic familial amyotrophic lateral sclerosisQ86613307
Neurofilament light antibodies in serum reflect response to natalizumab treatment in multiple sclerosisQ87269296
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteriaQ24605493
Neurofilament in CSF-A biomarker of disease activity and long-term prognosis in multiple sclerosisQ28276772
Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosisQ33605353
Combination of CSF N-acetylaspartate and neurofilaments in multiple sclerosisQ34975529
Increased neurofilament light chain blood levels in neurodegenerative neurological diseasesQ35000781
Glial and neuronal markers in cerebrospinal fluid predict progression in multiple sclerosisQ35330799
Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosisQ35537489
Exploration of machine learning techniques in predicting multiple sclerosis disease courseQ36335905
A model for the comprehensive investigation of a chronic autoimmune disease: the multiple sclerosis CLIMB studyQ36617521
The Effect of Fingolimod on Conversion of Acute Gadolinium-Enhancing Lesions to Chronic T1 Hypointensities in Multiple SclerosisQ37325966
Central fatigue in multiple sclerosis: a review of the literatureQ37404024
The challenge of multiple sclerosis: how do we cure a chronic heterogeneous disease?Q37427659
Serum neurofilament is associated with progression of brain atrophy and disability in early MS.Q38381437
Serum Neurofilament light: A biomarker of neuronal damage in multiple sclerosisQ38682945
Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and SimoaQ38882174
Serum neurofilament light chain levels are increased in patients with a clinically isolated syndromeQ39035274
Psychometric properties of the modified fatigue impact scaleQ39266465
Neurofilament protein in cerebrospinal fluid: a potential marker of activity in multiple sclerosis.Q40864697
A role for neurofilaments in the pathogenesis of amyotrophic lateral sclerosisQ41037886
Neurofilaments consist of distinct populations that can be distinguished by C-terminal phosphorylation, bundling, and axonal transport rate in growing axonal neurites.Q43551089
Axonal damage in relapsing multiple sclerosis is markedly reduced by natalizumab.Q44028578
The relationship between diffuse axonal damage and fatigue in multiple sclerosisQ44766912
Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcomeQ45284798
Neurofilament light chain predicts disease activity in relapsing-remitting MS.Q47138197
Monitoring disease activity in multiple sclerosis using serum neurofilament light proteinQ47144073
Serum neurofilament light in familial Alzheimer disease: A marker of early neurodegenerationQ47165587
Dual-Sensitivity Multiple Sclerosis Lesion and CSF Segmentation for Multichannel 3T Brain MRI.Q47918457
Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer DiseaseQ48243501
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative DiseasesQ48682038
Neurofilament light chain in cerebrospinal fluid and prediction of disease activity in clinically isolated syndrome and relapsing-remitting multiple sclerosis.Q51110507
Fatigue and declines in cognitive functioning in multiple sclerosis.Q51972539
Plasma neurofilament light chain levels in patients with MS switching from injectable therapies to fingolimod.Q53212006
Cerebrospinal fluid biomarkers of inflammation and degeneration as measures of fingolimod efficacy in multiple sclerosis.Q53624114
The prognostic value of CSF neurofilaments in multiple sclerosis at 15-year follow-up.Q53636788
P433issue12
P304page(s)1478-1491
P577publication date2018-10-16
P1433published inAnnals of clinical and translational neurologyQ27725312
P1476titleNeurofilament light chain serum levels correlate with 10-year MRI outcomes in multiple sclerosis
P478volume5

Reverse relations

cites work (P2860)
Q64970888Blood neurofilament light as a potential endpoint in Phase 2 studies in MS.
Q91897392Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in
Q90067056Does Resetting the Immune System Fix Multiple Sclerosis?
Q90088600High serum neurofilament light chain normalizes after hematopoietic stem cell transplantation for MS
Q64071842Neurofilament Light Chain as a Biomarker in Multiple Sclerosis
Q92814294Neurofilaments: The C-Reactive Protein of Neurology
Q99605557Obinutuzumab-Induced B Cell Depletion Reduces Spinal Cord Pathology in a CD20 Double Transgenic Mouse Model of Multiple Sclerosis
Q92774722Serum neurofilament light chain levels associations with gray matter pathology: a 5-year longitudinal study
Q96685857Serum neurofilament light chain predicts long term clinical outcomes in multiple sclerosis
Q99710478Serum neurofilament light chain: No clear relation to cognition and neuropsychiatric symptoms in stable MS