| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Luis Rojo | |
| Maria Rosa Aguilar | |||
| Daniel Fernández-Villa | |||
| P2860 | cites work | The use of trimethoprim and sulfamethoxazole (TMP-SMX) in dermatology | Q26771626 |
| Insights into antifolate resistance from malarial DHFR-TS structures | Q27641016 | ||
| Folate binding site of flavin-dependent thymidylate synthase | Q27673716 | ||
| Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes | Q27677355 | ||
| Structure and function of the dihydropteroate synthase from Staphylococcus aureus | Q27737332 | ||
| The folate cycle and disease in humans | Q28199731 | ||
| Mechanism of inhibition of dihydrofolate reductases from bacterial and vertebrate sources by various classes of folate analogues | Q28299487 | ||
| A bifunctional dihydrofolate synthetase--folylpolyglutamate synthetase in Plasmodium falciparum identified by functional complementation in yeast and bacteria | Q30040267 | ||
| Rosacea: II. Therapy | Q31115595 | ||
| Cloning, sequencing, and enhanced expression of the dihydropteroate synthase gene of Escherichia coli MC4100 | Q33204265 | ||
| Exposure to folic acid antagonists during the first trimester of pregnancy and the risk of major malformations | Q33608040 | ||
| Treatment of seborrheic dermatitis: a comprehensive review | Q88602727 | ||
| Dapsone, two birds with one stone: a response to "Dapsone advantages over trimethoprim-sulfamethoxazole for Pneumocystis pneumonia prophylaxis in immunobullous patients" | Q90154113 | ||
| Mechanistic insight into the activity of a sulfone compound dapsone on Propionibacterium (Newly Reclassified as Cutibacterium) Acnes-mediated cytokine production | Q90753589 | ||
| Toward a better understanding of folate metabolism in health and disease | Q90763945 | ||
| Methotrexate mechanism in treatment of rheumatoid arthritis | Q90776937 | ||
| Molecular docking and simulation study for synthesis of alternative dapsone derivative as a newer antileprosy drug in multidrug therapy | Q91042061 | ||
| Synthesis and Structure-Activity Relationship Studies of Benzo[b][1,4]oxazin-3(4H)-one Analogues as Inhibitors of Mycobacterial Thymidylate Synthase X | Q91289636 | ||
| pH-responsive chitosan based hydrogels affect the release of dapsone: Design, set-up, and physicochemical characterization | Q91607402 | ||
| Sulfonamide derivatives as multi-target agents for complex diseases | Q91618515 | ||
| Novel 5-substituted derivatives of 2'-deoxy-6-azauridine with antibacterial activity | Q91816187 | ||
| Antibiofilm Potential of Silver Sulfadiazine-Loaded Nanoparticle Formulations: A Study on the Effect of DNase-I on Microbial Biofilm and Wound Healing Activity | Q91987492 | ||
| Structure-Guided In Vitro to In Vivo Pharmacokinetic Optimization of Propargyl-Linked Antifolates | Q92760337 | ||
| Hyaluronic acid and chitosan-based nanosystems: a new dressing generation for wound care | Q92873951 | ||
| Non-Propellant Foams of Green Nano-Silver and Sulfadiazine: Development and In Vivo Evaluation for Burn Wounds | Q92891602 | ||
| Transformational exchanges in the dihydropteroate synthase gene of Neisseria meningitidis: a novel mechanism for acquisition of sulfonamide resistance | Q39940392 | ||
| Characterization of mutationally altered dihydropteroate synthase and its ability to form a sulfonamide-containing dihydrofolate analog | Q39978738 | ||
| Mechanisms of resistance to trimethoprim, the sulfonamides, and trimethoprim-sulfamethoxazole | Q40337561 | ||
| An historical and clinical review of the interaction of leprosy and pregnancy: a cycle to be broken | Q40767092 | ||
| Trimethoprim: mechanisms of action, antimicrobial activity, bacterial resistance, pharmacokinetics, adverse reactions, and therapeutic indications | Q40852647 | ||
| Adverse reactions to sulfisoxazole, sulfamethoxazole, and nitrofurantoin. Manifestations and specific reaction rates during 2,118 courses of therapy | Q40924011 | ||
| The properties of known drugs. 1. Molecular frameworks | Q40933327 | ||
| A review of the causes and treatment of bacterial and allergic conjunctivitis | Q40966339 | ||
| Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents | Q41365032 | ||
| Synthesis and evaluation of 5-substituted 2'-deoxyuridine monophosphate analogues as inhibitors of flavin-dependent thymidylate synthase in Mycobacterium tuberculosis | Q42732581 | ||
| Characterization of different plasmid-borne dihydropteroate synthases mediating bacterial resistance to sulfonamides | Q42835671 | ||
| Activity of topical antimicrobial agents against multidrug-resistant bacteria recovered from burn patients | Q43027802 | ||
| Bioadhesive sulfacetamide sodium microspheres: evaluation of their effectiveness in the treatment of bacterial keratitis caused by Staphylococcus aureus and Pseudomonas aeruginosa in a rabbit model. | Q45211841 | ||
| Rescue of pulmonary hypertension with an oral sulfonamide antibiotic sulfisoxazole by endothelin receptor antagonistic actions | Q46275600 | ||
| Sulfadiazine Salicylaldehyde-Based Schiff Bases: Synthesis, Antimicrobial Activity and Cytotoxicity. | Q46304589 | ||
| Mechanism-based inhibitors of folylpoly-gamma-glutamate synthetase and gamma-glutamyl hydrolase: control of folylpoly-gamma-glutamate homeostasis as a drug target | Q46356454 | ||
| Sulfisoxazole, an endothelin receptor antagonist, protects retinal neurones from insults of ischemia/reperfusion or lipopolysaccharide | Q46932691 | ||
| Sulfamethoxazole-Trimethoprim (Cotrimoxazole) for Skin and Soft Tissue Infections Including Impetigo, Cellulitis, and Abscess | Q47104755 | ||
| Enzymes of purine and pyrimidine metabolism from the human malaria parasite, Plasmodium falciparum | Q47975339 | ||
| Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT | Q48124895 | ||
| 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase. | Q48241249 | ||
| Topical Sulfamylon cream inhibits DNA and protein synthesis in the skin donor site wound | Q48698898 | ||
| Methotrexate preferentially affects Tc1 and Tc17 subset of CD8 T lymphocytes | Q49721652 | ||
| Guidelines for the Prevention and Treatment of Opportunistic Infections among HIV-exposed and HIV-infected children: recommendations from CDC, the National Institutes of Health, the HIV Medicine Association of the Infectious Diseases Society of Amer | Q33650105 | ||
| Folic acid: nutritional biochemistry, molecular biology, and role in disease processes | Q33918970 | ||
| Dapsone and sulfones in dermatology: overview and update | Q34087357 | ||
| Topical antimicrobials for burn wound infections | Q34111992 | ||
| Considerations when prescribing trimethoprim-sulfamethoxazole | Q34223201 | ||
| Dapsone in dermatology and beyond | Q34390020 | ||
| DNA and RNA synthesis: antifolates | Q34392383 | ||
| Inhibition of red cell membrane lipid peroxidation by sulphasalazine and 5-aminosalicylic acid | Q34395621 | ||
| Molecular mechanisms of antibacterial multidrug resistance | Q34611916 | ||
| Antibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study | Q35011012 | ||
| Molecular mechanisms of sulfasalazine-induced T-cell apoptosis | Q35044669 | ||
| Sulfonamide resistance mechanism in Escherichia coli: R plasmids can determine sulfonamide-resistant dihydropteroate synthases | Q35083819 | ||
| Synthesis of bi-substrate state mimics of dihydropteroate synthase as potential inhibitors and molecular probes | Q35138240 | ||
| Topical acne drugs: review of clinical properties, systemic exposure, and safety | Q35157487 | ||
| Resistance to antifolates | Q35567272 | ||
| Sulfadiazine-induced nephrolithiasis in children | Q35810169 | ||
| Folate-Dependent Purine Nucleotide Biosynthesis in Humans | Q36033696 | ||
| Comparative folate metabolism in humans and malaria parasites (part I): pointers for malaria treatment from cancer chemotherapy | Q36142613 | ||
| New Perspective on Impact of Folic Acid Supplementation during Pregnancy on Neurodevelopment/Autism in the Offspring Children - A Systematic Review | Q36201052 | ||
| Sulfasalazine: a review of its use in the management of rheumatoid arthritis | Q36237544 | ||
| Polymer-free electrospun nanofibers from sulfobutyl ether7-beta-cyclodextrin (SBE7-β-CD) inclusion complex with sulfisoxazole: Fast-dissolving and enhanced water-solubility of sulfisoxazole | Q36356550 | ||
| Folic acid metabolism and malaria | Q37093779 | ||
| Folylpolyglutamate synthase is a major determinant of intracellular methotrexate polyglutamates in patients with rheumatoid arthritis | Q37345390 | ||
| Topical antimicrobial agents for burn wounds | Q37606054 | ||
| Oxidative stress as a mechanism underlying sulfasalazine-induced toxicity. | Q37827164 | ||
| Dihydrofolate reductase as a therapeutic target for infectious diseases: opportunities and challenges | Q38026606 | ||
| The potential role of trimethoprim-sulfamethoxazole in the treatment of drug-resistant tuberculosis | Q38806183 | ||
| Designing dapsone polymer conjugates for controlled drug delivery | Q38839596 | ||
| Antibacterial Antifolates: From Development through Resistance to the Next Generation | Q38879756 | ||
| A systematic review and meta-analysis of the relative efficacy and safety of treatment regimens for HIV-associated cerebral toxoplasmosis: is trimethoprim-sulfamethoxazole a real option? | Q38879927 | ||
| Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers. | Q38991972 | ||
| Sulfisoxazole/cyclodextrin inclusion complex incorporated in electrospun hydroxypropyl cellulose nanofibers as drug delivery system. | Q39029574 | ||
| Otitis media of infancy and early childhood. A double-blind study of four treatment regimens | Q39111052 | ||
| Treatment of Acute Otitis Media of Infancy With Cefaclor | Q39220705 | ||
| Methotrexate and sulfasalazine promote adenosine release by a mechanism that requires ecto-5'-nucleotidase-mediated conversion of adenine nucleotides | Q39797150 | ||
| Inhibition of extracellular release of proinflammatory secretory phospholipase A2 (sPLA2) by sulfasalazine: a novel mechanism of anti-inflammatory activity. | Q52526726 | ||
| Passage of drugs across the placenta. | Q52766562 | ||
| Sulfonamide-Linked Ciprofloxacin, Sulfadiazine and Amantadine Derivatives as a Novel Class of Inhibitors of Jack Bean Urease; Synthesis, Kinetic Mechanism and Molecular Docking. | Q53099814 | ||
| Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis. | Q53165185 | ||
| Iclaprim, a dihydrofolate reductase inhibitor antibiotic in Phase III of clinical development: a review of its pharmacology, microbiology and clinical efficacy and safety. | Q53685312 | ||
| Sulfonamide resistance: mechanisms and trends. | Q53999423 | ||
| Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. | Q54516225 | ||
| MECHANISMS OF RESISTANCE OF ESCHERICHIA COLI TO SULFONAMIDES. | Q54718540 | ||
| The effect of mafenide on dihydropteroate synthase. | Q54720440 | ||
| Sulfonamide Inhibitors: a Patent Review 2013-Present. | Q54976604 | ||
| The downside of antimicrobial agents for wound healing | Q57021647 | ||
| Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target | Q58560484 | ||
| Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models | Q58603752 | ||
| Tissue Engineering Therapies Based on Folic Acid and Other Vitamin B Derivatives. Functional Mechanisms and Current Applications in Regenerative Medicine | Q60952836 | ||
| DHFR Inhibitors: Reading the Past for Discovering Novel Anticancer Agents | Q64062976 | ||
| Sulfasalazine reduces placental secretion of antiangiogenic factors, up-regulates the secretion of placental growth factor and rescues endothelial dysfunction | Q64099971 | ||
| Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A | Q64114197 | ||
| Tonsillar Membrane in the DDS (Dapsone) Syndrome | Q67899623 | ||
| Sulfisoxazole as chemoprophylaxis for recurrent otitis media. A double-blind crossover study in pediatric practice | Q70050270 | ||
| Mechanism of thymineless death | Q70149801 | ||
| Pharmacokinetic profile of sulfisoxazole following intravenous, intramuscular, and oral administration to man | Q70398317 | ||
| Properties of known drugs. 2. Side chains | Q73284123 | ||
| Computational Modelling of Dapsone Interaction With Dihydropteroate Synthase in Mycobacterium leprae; Insights Into Molecular Basis of Dapsone Resistance in Leprosy | Q87038502 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 20 | |
| P921 | main subject | folic acid | Q127060 |
| immunologic factor | Q50349184 | ||
| folic acid antagonists | Q50573407 | ||
| P577 | publication date | 2019-10-09 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | Folic Acid Antagonists: Antimicrobial and Immunomodulating Mechanisms and Applications | |
| P478 | volume | 20 |
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