3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice

scientific article published on 04 October 2019

3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice is …
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scholarly articleQ13442814

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P356DOI10.1038/S42003-019-0599-8
P932PMC publication ID6778135
P698PubMed publication ID31602409

P50authorLi-Huei TsaiQ9337816
Kwanghun ChungQ67218915
Heejin ChoiQ90644372
David A BennettQ66739430
P2093author name stringJun Wang
Jennie Z Young
Ivana Delalle
Wen-Chin Huang
Christine G Yao
Fatema Abdurrob
Lauren Ashley Watson
Rebecca Gail Canter
Stephanie M Bousleiman
P2860cites workMamillary body in the rat: topography and synaptology of projections from the subicular complex, prefrontal cortex, and midbrain tegmentumQ69225871
The specificity of pH and ionic strength effects on the kinetics of the Rh (D)-anti-Rh (D) systemQ69989159
Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer modelQ24603560
Thalamic pathology and memory loss in early Alzheimer's disease: moving the focus from the medial temporal lobe to Papez circuitQ26748827
Clarifying Tissue ClearingQ26799523
Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkersQ26825442
Neuropathological stageing of Alzheimer-related changesQ27860862
Fiji: an open-source platform for biological-image analysisQ27860912
The brain's default network: anatomy, function, and relevance to diseaseQ27860961
Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Q28082768
Monetary costs of dementia in the United StatesQ28288245
Simple, Scalable Proteomic Imaging for High-Dimensional Profiling of Intact SystemsQ28817946
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-BQ29012704
Alzheimer's disease: the amyloid cascade hypothesisQ29547160
Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairmentQ29547294
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's diseaseQ29614374
Default-mode network activity distinguishes Alzheimer's disease from healthy aging: evidence from functional MRIQ29619152
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's diseaseQ30080016
Chemogenetic inactivation of ventral hippocampal glutamatergic neurons disrupts consolidation of contextual fear memoryQ30407997
Disruption of functional connectivity in clinically normal older adults harboring amyloid burdenQ30492809
Amyloid beta from axons and dendrites reduces local spine number and plasticity.Q30511922
Seizures and epileptiform activity in the early stages of Alzheimer diseaseQ30577633
Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer DiseaseQ31142230
Rates of β-amyloid accumulation are independent of hippocampal neurodegenerationQ33581412
Early Brain Loss in Circuits Affected by Alzheimer's Disease is Predicted by Fornix Microstructure but may be Independent of Gray MatterQ33672857
Regional brain amyloid-β accumulation associates with domain-specific cognitive performance in Parkinson disease without dementiaQ33727909
Advanced CLARITY for rapid and high-resolution imaging of intact tissuesQ33896353
Single-cell phenotyping within transparent intact tissue through whole-body clearingQ34127451
Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer's diseaseQ34247849
Alzheimer's disease: cell-specific pathology isolates the hippocampal formationQ34261572
The evolution of psychiatric symptoms in Alzheimer's disease: a natural history studyQ34395540
TeraStitcher - a tool for fast automatic 3D-stitching of teravoxel-sized microscopy images.Q34488505
Longitudinal assessment of Aβ and cognition in aging and Alzheimer diseaseQ34606557
Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalisQ34717505
Large-scale topology and the default mode network in the mouse connectome.Q34830666
Synergistic effect of β-amyloid and neurodegeneration on cognitive decline in clinically normal individuals.Q34940642
Neuronal activity regulates the regional vulnerability to amyloid-β depositionQ35009626
Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performanceQ35227785
Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progressionQ35626520
Aberrant functional connectivity in Papez circuit correlates with memory performance in cognitively intact middle-aged APOE4 carriersQ35664370
Progression of Seed-Induced Aβ Deposition within the Limbic ConnectomeQ35931728
Attenuation of β-Amyloid Deposition and Neurotoxicity by Chemogenetic Modulation of Neural ActivityQ36456728
Neuron loss in the 5XFAD mouse model of Alzheimer's disease correlates with intraneuronal Aβ42 accumulation and Caspase-3 activationQ36556213
β-amyloid, hippocampal atrophy and their relation to longitudinal brain change in cognitively normal individualsQ36687792
Memory retrieval by activating engram cells in mouse models of early Alzheimer's diseaseQ36843600
Amyloid deposition is associated with impaired default network function in older persons without dementiaQ37335603
Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse modelQ37341124
Complement and microglia mediate early synapse loss in Alzheimer mouse models.Q37391481
How do mammillary body inputs contribute to anterior thalamic function?Q38238305
Distinct Neural Circuits for the Formation and Retrieval of Episodic MemoriesQ38617186
Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal PersonsQ38727771
The Cellular Phase of Alzheimer's DiseaseQ38731102
Gamma frequency entrainment attenuates amyloid load and modifies microgliaQ42631490
Limbic hypometabolism in Alzheimer's disease and mild cognitive impairmentQ44571913
In vivo staging of regional amyloid depositionQ47123732
Chronic optogenetic activation augments aβ pathology in a mouse model of Alzheimer diseaseQ47569266
CIDRE: an illumination-correction method for optical microscopyQ48216198
Synapse loss in the temporal lobe in Alzheimer's diseaseQ48338615
In vivo and post-mortem memory circuit integrity in frontotemporal dementia and Alzheimer's diseaseQ48362827
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.Q48404445
Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's diseaseQ48431425
The fornix and mammillary bodies in older adults with Alzheimer's disease, mild cognitive impairment, and cognitive complaints: a volumetric MRI studyQ48442570
Phases of A beta-deposition in the human brain and its relevance for the development of AD.Q48567985
Amyloid neuropathology in the single Arctic APP transgenic model affects interconnected brain regionsQ48924770
Synapse loss in frontal cortex biopsies in Alzheimer's disease: correlation with cognitive severityQ48983820
Amyloid imaging with (18)F-florbetaben in Alzheimer disease and other dementiasQ49039021
A disproportionate role for the fornix and mammillary bodies in recall versus recognition memory.Q51889738
NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease.Q52589491
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo.Q53274559
P304page(s)360
P577publication date2019-10-04
P1433published inCommunications BiologyQ60029756
P1476title3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice
P478volume2

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Q92380837Tissue clearing and its applications in neurosciencecites workP2860

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