Overcoming the Declining Trends in Innovation and Investment in Cardiovascular Therapeutics: Beyond EROOM's Law

scientific article published on 30 October 2017

Overcoming the Declining Trends in Innovation and Investment in Cardiovascular Therapeutics: Beyond EROOM's Law is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JACBTS.2017.09.002
P932PMC publication ID6058942
P698PubMed publication ID30062175

P2093author name stringGail A Van Norman
P2860cites workAngiotensin-neprilysin inhibition versus enalapril in heart failureQ28247091
Key cost drivers of pharmaceutical clinical trials in the United StatesQ28273573
Estimating the cost of new drug development: is it really 802 million dollars?Q28300812
Profitability and Market Value of Orphan Drug Companies: A Retrospective, Propensity-Matched Case-Control StudyQ28552860
How were new medicines discovered?Q29616641
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart AssociationQ30238784
Chronic diseases: the emerging pandemic.Q30404279
Balancing early market access to new drugs with the need for benefit/risk data: a mounting dilemmaQ33369050
Clinical trial evidence supporting FDA approval of novel therapeutic agents, 2005-2012.Q34089761
Pricing and reimbursement of orphan drugs: the need for more transparencyQ34193502
Diagnosing the decline in pharmaceutical R&D efficiencyQ34257771
How innovative are new drugs launched in the UK? A retrospective study of new drugs listed in the British National Formulary (BNF) 2001-2012Q34417204
Multidrug-resistant tuberculosis and culture conversion with bedaquiline.Q34434294
Drug-review deadlines and safety problemsQ34764725
How a patient advocacy group developed the first proposed draft guidance document for industry for submission to the U.S. Food and Drug AdministrationQ35801586
Trends in utilization of FDA expedited drug development and approval programs, 1987-2014: cohort studyQ36087521
Pharmaceutical innovation in the 21st century: new drug approvals in the first decade, 2000-2009.Q37824591
FDA designations for therapeutics and their impact on drug development and regulatory review outcomes.Q38351467
Cardiovascular drug development: is it dead or just hibernating?Q38424497
Varespladib and cardiovascular events in patients with an acute coronary syndrome: the VISTA-16 randomized clinical trialQ38441000
Innovative Clinical Trial Designs for Precision Medicine in Heart Failure with Preserved Ejection FractionQ38691846
Efficient design of clinical trials and epidemiological research: is it possible?Q38817527
Occlusion in the Flow of New Drugs for Cardiovascular Disease.Q39221282
Late-stage pharmaceutical R&D and pricing policies under two-stage regulationQ39253732
Evaluation of Therapeutics for Advanced-Stage Heart Failure and Other Severely-Debilitating or Life-Threatening Diseases.Q39285539
Challenges in the Development of Novel Cardiovascular TherapiesQ39393735
New approach to clinical trials and drug registration. Author's suggestions for drug approval are questionableQ42018848
2013 FDA drug approvalsQ44117034
Regulatory Consequences of "Brexit" for the Development of Medicinal ProductsQ47318390
Why it won't happen to me: perceptions of risk factors and susceptibility.Q51237042
Affairs of the Heart: Innovation in Cardiovascular Research and Development.Q53157206
Market watch: Are orphan drug companies the pick of the pharmaceutical industry?Q87016048
Era of faster FDA drug approval has also seen increased black-box warnings and market withdrawalsQ87504444
Intelligent pharmaceuticals: beyond the tipping pointQ87711989
P433issue5
P304page(s)613-625
P577publication date2017-10-30
P1433published inJACC. Basic to Translational ScienceQ27727237
P1476titleOvercoming the Declining Trends in Innovation and Investment in Cardiovascular Therapeutics: Beyond EROOM's Law
P478volume2

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cites work (P2860)
Q90356659Identification of amitriptyline HCl, flavin adenine dinucleotide, azacitidine and calcitriol as repurposing drugs for influenza A H5N1 virus-induced lung injury
Q64081820Overcoming Barriers to Development of Novel Therapies for Cardiovascular Disease
Q92619713Permeability of Epithelial/Endothelial Barriers in Transwells and Microfluidic Bilayer Devices
Q91943657Phase II Trials in Drug Development and Adaptive Trial Design

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