| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Bryan A Killinger | Q83203564 |
| Viviane Labrie | Q87780338 | ||
| P2860 | cites work | The prion hypothesis in Parkinson's disease: Braak to the future | Q22001062 |
| A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β. | Q24631193 | ||
| Modulation of adult hippocampal neurogenesis by early-life environmental challenges triggering immune activation. | Q27014755 | ||
| A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules | Q27308814 | ||
| Recirculating Intestinal IgA-Producing Cells Regulate Neuroinflammation via IL-10 | Q90908137 | ||
| Gut microbiota in neurodegenerative disorders | Q91113022 | ||
| A Neural Circuit for Gut-Induced Reward | Q91662368 | ||
| Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity | Q91825082 | ||
| Chronic Mild Gut Inflammation Accelerates Brain Neuropathology and Motor Dysfunction in α-Synuclein Mutant Mice | Q91953632 | ||
| Neuroprotection of Fasting Mimicking Diet on MPTP-Induced Parkinson's Disease Mice via Gut Microbiota and Metabolites | Q91993883 | ||
| Lipopolysaccharide from Gut Microbiota Modulates α-Synuclein Aggregation and Alters Its Biological Function | Q92266886 | ||
| Spreading of alpha-synuclein - relevant or epiphenomenon? | Q92454767 | ||
| Is Parkinson's disease a chronic low-grade inflammatory bowel disease? | Q93117850 | ||
| Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson's Disease | Q93128095 | ||
| The impact of perinatal immune development on mucosal homeostasis and chronic inflammation | Q95421092 | ||
| Structural and functional features of central nervous system lymphatic vessels | Q27316769 | ||
| Staging of brain pathology related to sporadic Parkinson's disease | Q28131702 | ||
| Biofilms in the large bowel suggest an apparent function of the human vermiform appendix | Q28253294 | ||
| Comparative anatomy and phylogenetic distribution of the mammalian cecal appendix | Q28254874 | ||
| Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43 | Q28509150 | ||
| Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin | Q29615449 | ||
| Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation | Q29615640 | ||
| The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions | Q29617847 | ||
| Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice | Q29620597 | ||
| Neuroprotective natural antibodies to assemblies of amyloidogenic peptides decrease with normal aging and advancing Alzheimer's disease. | Q30489052 | ||
| MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration | Q33625527 | ||
| Vagotomy and Parkinson disease: A Swedish register-based matched-cohort study | Q33714613 | ||
| Autoimmune antibody decline in Parkinson's disease and Multiple System Atrophy; a step towards immunotherapeutic strategies. | Q33776552 | ||
| Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations | Q33836384 | ||
| Reducing C-terminal-truncated alpha-synuclein by immunotherapy attenuates neurodegeneration and propagation in Parkinson's disease-like models | Q33865366 | ||
| Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry | Q33935711 | ||
| Appendectomy and protection against ulcerative colitis | Q33937912 | ||
| The epidemiology of appendicitis and appendectomy in the United States | Q34031030 | ||
| Vagotomy and subsequent risk of Parkinson's disease | Q34044141 | ||
| Human appendix B cells naturally express receptors for and respond to interleukin 6 with selective IgA1 and IgA2 synthesis | Q34225676 | ||
| The vermiform appendix: not a useless organ. | Q34330381 | ||
| Distribution of immunoglobulin producing cells is different in normal human appendix and colon mucosa | Q34529040 | ||
| Microbial composition of human appendices from patients following appendectomy. | Q34549255 | ||
| The appendix may protect against Clostridium difficile recurrence | Q34630580 | ||
| Parkinson's disease: a dual-hit hypothesis | Q34706775 | ||
| Observations on the epidemiology of appendicitis | Q35003876 | ||
| Distribution of CD4(pos) -, CD8(pos) - and regulatory T cells in the upper and lower gastrointestinal tract in healthy young subjects | Q35050631 | ||
| Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis | Q35060073 | ||
| Generation of colonic IgA-secreting cells in the caecal patch. | Q35144035 | ||
| Culture-independent evaluation of the appendix and rectum microbiomes in children with and without appendicitis | Q35156133 | ||
| ??? | Q64865233 | ||
| ??? | Q64868147 | ||
| ??? | Q64869745 | ||
| A Role for Neuronal Alpha-Synuclein in Gastrointestinal Immunity. | Q40157769 | ||
| T cells from patients with Parkinson's disease recognize α-synuclein peptides | Q40163812 | ||
| Appendectomy and risk of Parkinson's disease: A nationwide cohort study with more than 10 years of follow-up | Q40584559 | ||
| Pathological α-synuclein transmission initiated by binding lymphocyte-activation gene 3. | Q41015843 | ||
| Interactions of Intestinal Bacteria with Components of the Intestinal Mucus | Q41450553 | ||
| Peripheral cytokines profile in Parkinson's disease. | Q42439761 | ||
| Co-expression of C-terminal truncated alpha-synuclein enhances full-length alpha-synuclein-induced pathology. | Q42939567 | ||
| Importance of motor vs. non-motor symptoms for health-related quality of life in early Parkinson's disease | Q43745572 | ||
| Acute Appendicitis in Children Is Associated With a Local Expansion of Fusobacteria | Q44480774 | ||
| Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining | Q44766877 | ||
| Blood-brain barrier dysfunction in parkinsonian midbrain in vivo | Q45237161 | ||
| Colonic inflammation in Parkinson's disease. | Q46015750 | ||
| Phenotypically distinct subpopulations of T cells in domes and M-cell pockets of rabbit gut-associated lymphoid tissues. | Q46608298 | ||
| Adult Hippocampal Neurogenesis Is Regulated by the Microbiome | Q46769891 | ||
| Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology | Q47552497 | ||
| Role of alpha-synuclein carboxy-terminus on fibril formation in vitro | Q47762431 | ||
| CD5+ B cells are preferentially expanded in rabbit appendix: the role of CD5 in B cell development and selection | Q48107500 | ||
| Association of circulating TNF-alpha and IL-6 with ageing and parkinsonism | Q48154893 | ||
| Role of commensal bacteria in development of gut-associated lymphoid tissues and preimmune antibody repertoire | Q48212386 | ||
| Appendectomy in mid and later life and risk of Parkinson's disease: A population-based study | Q48706676 | ||
| B cell activation in the cecal patches during the development of an experimental colitis model | Q50060093 | ||
| Interaction of pathogenic bacteria with rabbit appendix M cells: bacterial motility is a key feature in vivo | Q50099261 | ||
| β-Amyloid accumulation in the human brain after one night of sleep deprivation. | Q52597873 | ||
| Alteration of the fecal microbiota in Chinese patients with Parkinson's disease. | Q52675729 | ||
| Long term follow-up of appendiceal and distal right-sided colonic inflammation. | Q53393512 | ||
| Secretory immunoglobulin A (sIgA) deficiency in serum of patients with GALTectomy (appendectomy and tonsillectomy). | Q53558101 | ||
| A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly. | Q54031652 | ||
| Parkinson's disease | Q54072241 | ||
| Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson's disease. | Q54587822 | ||
| Magnetic resonance imaging provides evidence of glymphatic drainage from human brain to cervical lymph nodes. | Q55196138 | ||
| Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease | Q56336013 | ||
| CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature | Q57446154 | ||
| The risk of Parkinson's disease in inflammatory bowel disease: A systematic review and meta-analysis | Q57492629 | ||
| The vermiform appendix impacts the risk of developing Parkinson's disease | Q58091983 | ||
| A Systematic Review and Meta-Analysis of Alpha Synuclein Auto-Antibodies in Parkinson's Disease | Q58592665 | ||
| Microbiota-derived short-chain fatty acids promote Th1 cell IL-10 production to maintain intestinal homeostasis | Q58769405 | ||
| GABA-modulating bacteria of the human gut microbiota | Q59455083 | ||
| CD3+ B-1a Cells as a Mediator of Disease Progression in Autoimmune-Prone Mice | Q60935650 | ||
| The Gut and Parkinson's Disease: Hype or Hope? | Q60950153 | ||
| Appendectomy may delay Parkinson's disease Onset | Q62597318 | ||
| Circulating interleukin-15 and RANTES chemokine in Parkinson’s disease | Q63487622 | ||
| Inflammatory Bowel Disease and Parkinson’s Disease: A Nationwide Swedish Cohort Study | Q63537279 | ||
| The neuroactive potential of the human gut microbiota in quality of life and depression | Q63589897 | ||
| Human stem cells transplanted into the rat stroke brain migrate to the spleen via lymphatic and inflammation pathways | Q64074854 | ||
| Blocking meningeal lymphatic drainage aggravates Parkinson's disease-like pathology in mice overexpressing mutated α-synuclein | Q64085132 | ||
| Dural lymphatics regulate clearance of extracellular tau from the CNS | Q64096553 | ||
| Monomeric α-synuclein induces blood-brain barrier dysfunction through activated brain pericytes releasing inflammatory mediators in vitro | Q64774305 | ||
| Gut-brain axis and the spread of α-synuclein pathology: Vagal highway or dead end? | Q64785264 | ||
| The appendix and the risk of Parkinson's disease: Appended notes on correlation and causation | Q64786371 | ||
| Role of TLR4 in the gut-brain axis in Parkinson's disease: a translational study from men to mice | Q64787911 | ||
| Appendectomy and risk of Parkinson's disease in two large prospective cohorts of men and women | Q64860085 | ||
| Safety and Tolerability of Multiple Ascending Doses of PRX002/RG7935, an Anti-α-Synuclein Monoclonal Antibody, in Patients With Parkinson Disease: A Randomized Clinical Trial | Q64866693 | ||
| Anti-Tumor Necrosis Factor Therapy and Incidence of Parkinson Disease Among Patients With Inflammatory Bowel Disease | Q64876812 | ||
| Identification of a highly neurotoxic α-synuclein species inducing mitochondrial damage and mitophagy in Parkinson's disease | Q64976796 | ||
| Neuroprotective effects of fecal microbiota transplantation on MPTP-induced Parkinson's disease mice: Gut microbiota, glial reaction and TLR4/TNF-α signaling pathway. | Q67208769 | ||
| Production of immunoglobulin isotypes by Ly-1+ B cells in viable motheaten and normal mice | Q68799293 | ||
| Serum immunoglobulin levels and naturally occurring antibodies against carbohydrate antigens in germ-free BALB/c mice fed chemically defined ultrafiltered diet | Q69416820 | ||
| Appendectomy protects against ulcerative colitis | Q72401639 | ||
| Phenotypic pattern of B cells in the appendix: reduced intensity of CD19 expression | Q73702571 | ||
| Role of appendix and spleen in experimental colitis | Q77326686 | ||
| Age-dependent variation in the proportion and number of intestinal lymphocyte subsets, especially natural killer T cells, double-positive CD4+ CD8+ cells and B220+ T cells, in mice | Q80898523 | ||
| Bacterial translocation in the normal human appendix parallels the development of the local immune system | Q81341641 | ||
| Does vagotomy reduce the risk of Parkinson's disease? | Q86311590 | ||
| Regulatory T cells in autoimmune disease | Q89171054 | ||
| Microanatomical dissection of human intestinal T-cell immunity reveals site-specific changes in gut-associated lymphoid tissues over life | Q90317935 | ||
| Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer's dementia subjects | Q90586078 | ||
| The vermiform appendix: an immunological organ sustaining a microbiome inoculum | Q90870446 | ||
| Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats | Q35313910 | ||
| Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis | Q35366986 | ||
| Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death | Q35484581 | ||
| Gut microbiota are related to Parkinson's disease and clinical phenotype | Q35492461 | ||
| Human B-1 cells take the stage | Q35600416 | ||
| Targeting T cell responses by selective chemokine receptor expression | Q35682772 | ||
| Comparative study of the intestinal mucus barrier in normal and inflamed colon. | Q35761363 | ||
| The Central Nervous System and the Gut Microbiome. | Q36182979 | ||
| Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease | Q36212145 | ||
| Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice | Q36367158 | ||
| Positive selection of the peripheral B cell repertoire in gut-associated lymphoid tissues | Q36402522 | ||
| Cytolytic activity of intestinal intraepithelial lymphocytes in germ-free mice is strain dependent and determined by T cells expressing gamma delta T-cell antigen receptors | Q36540931 | ||
| Alpha-Synuclein Expression Restricts RNA Viral Infections in the Brain | Q36736658 | ||
| Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease. | Q37036090 | ||
| Caudo-rostral brain spreading of α-synuclein through vagal connections | Q37040842 | ||
| Non-motor symptoms in Parkinson's disease | Q37114116 | ||
| Appendicitis, mesenteric lymphadenitis, and subsequent risk of ulcerative colitis: cohort studies in Sweden and Denmark | Q37136968 | ||
| Neonatal systemic exposure to lipopolysaccharide enhances susceptibility of nigrostriatal dopaminergic neurons to rotenone neurotoxicity in later life | Q37182878 | ||
| Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegans | Q37315005 | ||
| Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells | Q37446544 | ||
| Reversible microbial colonization of germ-free mice reveals the dynamics of IgA immune responses | Q37581953 | ||
| Role of the faecolith in modern-day appendicitis. | Q38073931 | ||
| Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects | Q38377819 | ||
| Pathological α-synuclein in gastrointestinal tissues from prodromal Parkinson disease patients | Q38381460 | ||
| Probiotics and prebiotic fiber for constipation associated with Parkinson disease: An RCT. | Q38388604 | ||
| Functional implications of microbial and viral gut metagenome changes in early stage L-DOPA-naïve Parkinson's disease patients. | Q38690133 | ||
| Appendectomy History is not Related to Parkinson's Disease | Q38733661 | ||
| Microbial induction of B and T cell areas in rabbit appendix | Q38783232 | ||
| Neuropathological basis of nonmotor manifestations of Parkinson's disease | Q38794098 | ||
| Alpha-Synuclein, a Novel Viral Restriction Factor Hiding in Plain Sight | Q38955003 | ||
| Brain-to-stomach transfer of α-synuclein via vagal preganglionic projections. | Q39067303 | ||
| Interactions between the microbiota, immune and nervous systems in health and disease. | Q39090621 | ||
| Brain Autoimmunity and Intestinal Microbiota: 100 Trillion Game Changers | Q39364276 | ||
| Effect of appendicectomy on colonic inflammation and neoplasia in experimental ulcerative colitis. | Q39513693 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial 4.0 International | Q34179348 |
| P433 | issue | s2 | |
| P921 | main subject | Parkinson's disease | Q11085 |
| lymphatic system | Q712604 | ||
| inflammatory bowel diseases | Q917447 | ||
| P304 | page(s) | S345-S358 | |
| P577 | publication date | 2019-01-01 | |
| P1433 | published in | Journal of Parkinson's disease | Q26842319 |
| P1476 | title | The Appendix in Parkinson's Disease: From Vestigial Remnant to Vital Organ? | |
| P478 | volume | 9 |
| Q97066892 | Parkinson's Disease and the Gut: Future Perspectives for Early Diagnosis | cites work | P2860 |
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