Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis

scientific article published on 19 December 2018

Safety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TRSL.2018.12.002
P698PubMed publication ID30615845

P50authorSandra MoralesQ91164279
Alkis J PsaltisQ80550747
P2093author name stringPeter-John Wormald
Sarah Vreugde
John W Finnie
Sathish Paramasivan
Mian Li Ooi
Amanda J Drilling
Stephanie A Fong
P2860cites workA controlled clinical trial of a therapeutic bacteriophage preparation in chronic otitis due to antibiotic-resistant Pseudomonas aeruginosa ; a preliminary report of efficacyQ22061813
Bacteriophage therapyQ24550616
Phage Therapy: a Step Forward in the Treatment of Pseudomonas aeruginosa InfectionsQ26823401
Pseudomonas aeruginosa keratitis in mice: effects of topical bacteriophage KPP12 administrationQ28484466
Quantification of biofilm structures by the novel computer program comstatQ28547921
The biofilm matrixQ29547334
Efficacy of NVC-422 against Staphylococcus aureus biofilms in a sheep biofilm model of sinusitisQ83706542
EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologistsQ83792713
Bacterial biofilms in chronic rhinosinusitis and their relationship with inflammation severityQ84274195
Topical treatment of Pseudomonas aeruginosa otitis of dogs with a bacteriophage mixture: a before/after clinical trialQ84565387
In vitro management of hospital Pseudomonas aeruginosa biofilm using indigenous T7-like lytic phageQ84742668
The bacteriology of chronic rhinosinusitis and the pre-eminence of Staphylococcus aureus in revision patientsQ86299608
Antimicrobial susceptibility of Gram-negative organisms isolated from patients hospitalised with pneumonia in US and European hospitals: results from the SENTRY Antimicrobial Surveillance Program, 2009-2012Q87444358
Confocal scanning laser microscopy evidence of biofilms in patients with chronic rhinosinusitisQ33289454
A sheep model for the study of biofilms in rhinosinusitisQ33290402
An in vitro model of Pseudomonas aeruginosa biofilms on viable airway epithelial cell monolayersQ33347644
Bacteriophage cocktail for the prevention of biofilm formation by Pseudomonas aeruginosa on catheters in an in vitro model system.Q33509952
Phage neutralization by sera of patients receiving phage therapyQ33828266
Pulmonary bacteriophage therapy on Pseudomonas aeruginosa cystic fibrosis strains: first steps towards treatment and preventionQ33828309
Nasal and sinus symptoms and chronic rhinosinusitis in a population-based sampleQ33872652
Human volunteers receiving Escherichia coli phage T4 orally: a safety test of phage therapyQ33883731
Quantitative analysis of in vivo mucosal bacterial biofilmsQ34152474
Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposisQ34531349
Bacteriophages: an appraisal of their role in the treatment of bacterial infectionsQ34637115
Prevalence of biofilm-forming bacteria in chronic rhinosinusitis.Q34790316
Epidemiology of chronic rhinosinusitis: results from a cross-sectional survey in seven Chinese citiesQ35535822
Characterization of the Newly Isolated Lytic Bacteriophages KTN6 and KT28 and Their Efficacy against Pseudomonas aeruginosa BiofilmQ35634231
Bacteriophages φMR299-2 and φNH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cellsQ35827006
The bacterial microbiome in chronic rhinosinusitis: Richness, diversity, postoperative changes, and patient outcomesQ35921109
Phage ΦPan70, a Putative Temperate Phage, Controls Pseudomonas aeruginosa in Planktonic, Biofilm and Burn Mouse Model AssaysQ36076253
Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activitiesQ36156448
Persistence of nasal colonization with human pathogenic bacteria and associated antimicrobial resistance in the German general populationQ36446023
A novel bacteriophage cocktail reduces and disperses Pseudomonas aeruginosa biofilms under static and flow conditionsQ36483482
National burden of antibiotic use for adult rhinosinusitisQ37274979
Relationship between clinical measures and histopathologic findings in chronic rhinosinusitisQ37397934
Different biofilms, different disease? A clinical outcomes studyQ37773865
Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies.Q38123588
Discrimination of bacteriophage infected cells using locked nucleic acid fluorescent in situ hybridization (LNA-FISH).Q40816973
An in vivo safety and efficacy demonstration of a topical liposomal nitric oxide donor treatment for Staphylococcus aureus biofilm-associated rhinosinusitisQ41112387
The multifaceted roles of antibiotics and antibiotic resistance in natureQ41249257
Disrupting the mixed-species biofilm of Klebsiella pneumoniae B5055 and Pseudomonas aeruginosa PAO using bacteriophages alone or in combination with xylitolQ41275723
Activity of Bacteriophages in Removing Biofilms of Pseudomonas aeruginosa Isolates from Chronic Rhinosinusitis PatientsQ41919523
Bacteriophage ecology in Escherichia coli and Pseudomonas aeruginosa mixed-biofilm communitiesQ42103948
Safety and efficacy of topical bacteriophage and ethylenediaminetetraacetic acid treatment of Staphylococcus aureus infection in a sheep model of sinusitisQ42241966
The Economic Burden and Symptom Manifestations of Chronic RhinosinusitisQ44136994
Evidence of bacterial biofilms in a rabbit model of sinusitis.Q52563412
Chronic rhinosinusitis in Europe--an underestimated disease. A GA²LEN study.Q53153166
CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients.Q53195491
Electron Microscopy Assessment of the Recovery of Sinus Mucosa after Sinus SurgeryQ58190053
Use of newly isolated phages for control of Pseudomonas aeruginosa PAO1 and ATCC 10145 biofilmsQ60649764
Economic implications of chronic sinusitisQ74397820
Tissue eosinophilia in chronic sinusitis: quantification techniquesQ74512531
P921main subjectphage therapyQ611870
Pseudomonas aeruginosaQ31856
bacteriophageQ165028
P304page(s)41-56
P577publication date2018-12-19
P1433published inTranslational ResearchQ15761127
P1476titleSafety and efficacy of a bacteriophage cocktail in an in vivo model of Pseudomonas aeruginosa sinusitis
P478volume206

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cites work (P2860)
Q92067725Detection of virulence and multidrug resistance operons in Pseudomonas aeruginosa isolated from Egyptian Baladi sheep and goat
Q90567977Exacerbations of Chronic Rhinosinusitis-Microbiology and Perspectives of Phage Therapy

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