Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action

scientific article published on 30 August 2018

Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/ACSCHEMBIO.8B00692
P698PubMed publication ID30137962

P50authorDanette DanielsQ59753598
Marjeta UrhQ90470391
Kristin M RichingQ123019436
Mark G McDougallQ123019459
Sarah MahanQ123019464
Cesear CoronaQ123019476
P2093author name stringMatthew B Robers
James D Vasta
P2860cites workMultiplex genome engineering using CRISPR/Cas systemsQ24609428
P433issue9
P304page(s)2758-2770
P577publication date2018-08-30
P1433published inACS Chemical BiologyQ165583
P1476titleQuantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action
P478volume13

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cites work (P2860)
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Q61809000Bivalent Ligands for Protein Degradation in Drug Discovery
Q91623240Bromodomains: a new target class for drug development
Q89810816Characterization of cereblon-dependent targeted protein degrader by visualizing the spatiotemporal ternary complex formation in cells
Q90719868Critical Assessment of Targeted Protein Degradation as a Research Tool and Pharmacological Modality
Q92189593Developing degraders: principles and perspectives on design and chemical space
Q111442197Development of BromoTag: A “Bump-and-Hole”–PROTAC System to Induce Potent, Rapid, and Selective Degradation of Tagged Target Proteins
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Q90476060NanoBiT Complementation to Monitor Agonist-Induced Adenosine A1 Receptor Internalization
Q98159741Native Mass Spectrometry Can Effectively Predict PROTAC Efficacy
Q90412606PROTAC Technology: Opportunities and Challenges
Q90186445PROTACs- a game-changing technology
Q92310282PROTACs: great opportunities for academia and industry
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Q96019158PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics
Q64269515SPR-Measured Dissociation Kinetics of PROTAC Ternary Complexes Influence Target Degradation Rate
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Q96431675Targeted protein degradation as a powerful research tool in basic biology and drug target discovery
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Q89926094The luminescent HiBiT peptide enables selective quantitation of GPCR ligand engagement and internalization in living cells
Q99557852Understanding and Improving the Membrane Permeability of VH032-Based PROTACs

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