Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells

scientific article published on 05 November 2019

Impact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-019-52442-9
P932PMC publication ID6831606
P698PubMed publication ID31690774

P50authorPierre LayrolleQ38360448
P2093author name stringKamal Mustafa
Jan E Brinchmann
Tommy A Karlsen
Samih Mohamed-Ahmed
Daniela E Costea
Jerome Amiaud
Salwa Suliman
Hassan R W Ali
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Cryopreserved mesenchymal stromal cell treatment is safe and feasible for severe dilated ischemic cardiomyopathyQ43251718
Platelet lysates promote mesenchymal stem cell expansion: a safety substitute for animal serum in cell-based therapy applicationsQ43898390
CD34+CDw90(Thy-1)+ subset colocated with mesenchymal progenitors in human normal bone marrow hematon units is enriched in colony-forming unit megakaryocytes and long-term culture-initiating cellsQ44684687
Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2cQ44998864
Platelet lysate suppresses the expression of lipocalin-type prostaglandin D2 synthase that positively controls adipogenic differentiation of human mesenchymal stromal cellsQ45417013
Generation of a pool of human platelet lysate and efficient use in cell culture.Q45992553
Platelet lysate favours in vitro expansion of human bone marrow stromal cells for bone and cartilage engineeringQ46308801
Xeno-Free Strategies for Safe Human Mesenchymal Stem/Stromal Cell Expansion: Supplements and CoatingsQ47151826
CRISPR/Cas9 Genome-Editing System in Human Stem Cells: Current Status and Future Prospects.Q47161696
Oct4 and Nanog directly regulate Dnmt1 to maintain self-renewal and undifferentiated state in mesenchymal stem cells.Q47386441
Standardized isolation of human mesenchymal stromal cells with red blood cell lysis.Q50541811
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Adipose-derived and bone marrow mesenchymal stem cells: a donor-matched comparison.Q55432734
Defined serum- and xeno-free cryopreservation of mesenchymal stem cellsQ57094520
Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trialQ58793452
Immunoregulatory potential of mesenchymal stem cells following activation by macrophage-derived soluble factorsQ64243123
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Insensitivity of Human iPS Cells-Derived Mesenchymal Stem Cells to Interferon-γ-induced HLA Expression Potentiates Repair Efficiency of Hind Limb Ischemia in Immune Humanized NOD Scid Gamma MiceQ85593180
Ex vivo gene therapy using human bone marrow cells overexpressing BMP-2: "Next-day" gene therapy versus standard "two-step" approachQ92526186
HLA-DR expression in clinical-grade bone marrow-derived multipotent mesenchymal stromal cells: a two-site studyQ92727720
Levels of IL-17F and IL-33 correlate with HLA-DR activation in clinical-grade human bone marrow-derived multipotent mesenchymal stromal cell expansion culturesQ93191163
Expression of inflammatory cytokines in mesenchymal stromal cells is sensitive to culture conditions and simple cell manipulationsQ93368968
P433issue1
P304page(s)16031
P577publication date2019-11-05
P1433published inScientific ReportsQ2261792
P1476titleImpact of humanised isolation and culture conditions on stemness and osteogenic potential of bone marrow derived mesenchymal stromal cells
P478volume9