| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Jeffrey H Kordower | Q67168846 |
| Ronald Melki | Q30123639 | ||
| P2093 | author name string | Patrik Brundin | |
| Bryan A Killinger | |||
| P2860 | cites work | Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson's disease brain | Q24321216 |
| A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP | Q24339494 | ||
| Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement | Q24569788 | ||
| α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation | Q24605589 | ||
| Energy transfer: a spectroscopic ruler | Q24618609 | ||
| Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro | Q24629968 | ||
| Definition of a molecular pathway mediating α-synuclein neurotoxicity | Q26269832 | ||
| α-Synuclein assembles into higher-order multimers upon membrane binding to promote SNARE complex formation | Q26269838 | ||
| Properties of native brain α-synuclein | Q26269846 | ||
| Biophysical characterization of α-synuclein and its controversial structure | Q26828504 | ||
| The Synaptic Function of α-Synuclein | Q27694711 | ||
| Alpha-synuclein in Lewy bodies | Q27860680 | ||
| Imaging intracellular fluorescent proteins at nanometer resolution | Q27860767 | ||
| Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein | Q28511573 | ||
| Expression of alpha-synuclein, a presynaptic protein implicated in Parkinson's disease, in erythropoietic lineage | Q28512712 | ||
| Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons | Q28567029 | ||
| Membrane-bound alpha-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form | Q28567172 | ||
| Genetic deletion of the GATA1-regulated protein α-synuclein reduces oxidative stress and nitric oxide synthase levels in mature erythrocytes | Q28591516 | ||
| Characterization of α-Synuclein Multimer Stoichiometry in Complex Biological Samples by Electrophoresis | Q28828388 | ||
| Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes | Q29617606 | ||
| Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis | Q79362817 | ||
| The newly discovered Parkinson's disease associated Finnish mutation (A53E) attenuates α-synuclein aggregation and membrane binding | Q85652193 | ||
| Fluorescence Anisotropy Reloaded-Emerging Polarization Microscopy Methods for Assessing Chromophores' Organization and Excitation Energy Transfer in Single Molecules, Particles, Films, and Beyond | Q91353293 | ||
| Studying α-Synuclein Conformation by Intact-Cell Cross-Linking | Q91639632 | ||
| Time course and magnitude of alpha-synuclein inclusion formation and nigrostriatal degeneration in the rat model of synucleinopathy triggered by intrastriatal α-synuclein preformed fibrils | Q91652831 | ||
| Reprint of "Ganglioside lipids accelerate α-synuclein amyloid formation" | Q92411785 | ||
| Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes | Q93001087 | ||
| Conformational properties of alpha-synuclein in its free and lipid-associated states | Q43564642 | ||
| Defective membrane interactions of familial Parkinson's disease mutant A30P alpha-synuclein | Q43866953 | ||
| Lipid binding inhibits alpha-synuclein fibril formation | Q44350640 | ||
| A structural and functional role for 11-mer repeats in alpha-synuclein and other exchangeable lipid binding proteins | Q44466072 | ||
| alpha-Synuclein-synaptosomal membrane interactions: implications for fibrillogenesis | Q44986582 | ||
| Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers | Q46241023 | ||
| Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinson's Disease | Q46263072 | ||
| Alpha-synuclein oligomers: a new hope. | Q46321755 | ||
| Binding of alpha-synuclein affects the lipid packing in bilayers of small vesicles | Q46925606 | ||
| GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers | Q47193126 | ||
| Pathological role of lipid interaction with α-synuclein in Parkinson's disease | Q47228027 | ||
| Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. | Q47241738 | ||
| Morphogenesis of Lewy bodies: dissimilar incorporation of alpha-synuclein, ubiquitin, and p62. | Q47300849 | ||
| Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry | Q47737272 | ||
| Loss of native α-synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells | Q47801119 | ||
| A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci. | Q47823702 | ||
| Alpha-synuclein has a high affinity for packing defects in a bilayer membrane: a thermodynamics study | Q47930930 | ||
| Alpha-Synuclein Disease Mutations Are Structurally Defective and Locally Affect Membrane Binding. | Q48121050 | ||
| β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease. | Q48131649 | ||
| Lipidomics unveils the complexity of the lipidome in metabolic diseases | Q48157430 | ||
| Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies. | Q48279657 | ||
| Accumulation of alpha-synuclein/NACP is a cytopathological feature common to Lewy body disease and multiple system atrophy | Q48342277 | ||
| Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. | Q48384247 | ||
| Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions. | Q48581414 | ||
| Relationships between Lewy bodies and pale bodies in Parkinson's disease. | Q48600286 | ||
| Similarities between neuronal Lewy bodies in parkinsonism and hepatic Mallory bodies in alcoholism. | Q48923249 | ||
| α-Synuclein may cross-bridge v-SNARE and acidic phospholipids to facilitate SNARE-dependent vesicle docking. | Q49266303 | ||
| Pale neurites, premature α-synuclein aggregates with centripetal extension from axon collaterals. | Q50532472 | ||
| Emerging Roles for the Lysosome in Lipid Metabolism. | Q51801045 | ||
| In Situ Proximity Ligation Assay Reveals Co-Localization of Alpha-Synuclein and SNARE Proteins in Murine Primary Neurons. | Q52330497 | ||
| Membrane binding and self-association of alpha-synucleins. | Q52543652 | ||
| The localization of α-synuclein in the process of differentiation of human erythroid cells. | Q52716959 | ||
| A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly. | Q54031652 | ||
| Different Conformational Subensembles of the Intrinsically Disordered Protein α-Synuclein in Cells. | Q54945931 | ||
| The systematic analysis of protein–lipid interactions comes of age | Q56989167 | ||
| Interplay between α-synuclein amyloid formation and membrane structure | Q57052511 | ||
| Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease | Q57285629 | ||
| Disruptive membrane interactions of alpha-synuclein aggregates | Q57477745 | ||
| Mapping Long-Range Interactions in α-Synuclein using Spin-Label NMR and Ensemble Molecular Dynamics Simulations | Q57976902 | ||
| Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson's disease model | Q58722552 | ||
| Methyl-branched lipids promote the membrane adsorption of α-synuclein by enhancing shallow lipid-packing defects | Q60456080 | ||
| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Q62666878 | ||
| Dysregulated Lipid Metabolism and Its Role in α-Synucleinopathy in Parkinson's Disease | Q64054875 | ||
| Lipids at the Crossroad of α-Synuclein Function and Dysfunction: Biological and Pathological Implications | Q64074236 | ||
| Defining α-synuclein species responsible for Parkinson's disease phenotypes in mice | Q64764687 | ||
| In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies | Q64764806 | ||
| Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment | Q64795552 | ||
| Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics | Q64814698 | ||
| Effects of phosphatidylcholine membrane fluidity on the conformation and aggregation of N-terminally acetylated α-synuclein | Q64868712 | ||
| Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling. | Q64923983 | ||
| Synapsins regulate α-synuclein functions. | Q64950988 | ||
| alpha-Synuclein immunoreactivity in dementia with Lewy bodies: morphological staging and comparison with ubiquitin immunostaining | Q73727325 | ||
| alpha-Synuclein membrane interactions and lipid specificity | Q74071513 | ||
| Adsorption of α-synuclein to supported lipid bilayers: positioning and role of electrostatics | Q30428288 | ||
| α-Synuclein mutations cluster around a putative protein loop | Q30430404 | ||
| Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae | Q30481396 | ||
| Alpha-synuclein redistributes to neuromelanin lipid in the substantia nigra early in Parkinson's disease. | Q30856480 | ||
| Early aggregation steps in alpha-synuclein as measured by FCS and FRET: evidence for a contagious conformational change. | Q33550002 | ||
| Lipids in cell biology: how can we understand them better? | Q33747083 | ||
| alpha-Synuclein occurs in lipid-rich high molecular weight complexes, binds fatty acids, and shows homology to the fatty acid-binding proteins | Q33929879 | ||
| Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra | Q33938966 | ||
| The novel Parkinson's disease linked mutation G51D attenuates in vitro aggregation and membrane binding of α-synuclein, and enhances its secretion and nuclear localization in cells. | Q33991720 | ||
| The lipid-binding domain of wild type and mutant alpha-synuclein: compactness and interconversion between the broken and extended helix forms | Q34107467 | ||
| A broken alpha -helix in folded alpha -Synuclein | Q34177224 | ||
| The association of alpha-synuclein with membranes affects bilayer structure, stability, and fibril formation | Q34217806 | ||
| α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer | Q34252869 | ||
| Direct observation of the interconversion of normal and toxic forms of α-synuclein | Q34277399 | ||
| Identification of a helical intermediate in trifluoroethanol-induced alpha-synuclein aggregation | Q34279026 | ||
| α-Synucleinopathy phenotypes | Q34386816 | ||
| Mutations associated with familial Parkinson's disease alter the initiation and amplification steps of α-synuclein aggregation | Q34538864 | ||
| Acute increase of α-synuclein inhibits synaptic vesicle recycling evoked during intense stimulation. | Q34572258 | ||
| Effects of curvature and composition on α-synuclein binding to lipid vesicles | Q34590790 | ||
| Quantification of alpha-synuclein binding to lipid vesicles using fluorescence correlation spectroscopy | Q34646732 | ||
| In vivo demonstration that alpha-synuclein oligomers are toxic | Q34652122 | ||
| Alpha-synuclein function and dysfunction on cellular membranes | Q34774324 | ||
| The many faces of α-synuclein: from structure and toxicity to therapeutic target | Q34972009 | ||
| Purification of α-synuclein from human brain reveals an instability of endogenous multimers as the protein approaches purity. | Q35001178 | ||
| Acceleration of α-synuclein aggregation by exosomes | Q35048929 | ||
| A new method for quantitative immunoblotting of endogenous α-synuclein | Q35054003 | ||
| Increased expression of alpha-synuclein reduces neurotransmitter release by inhibiting synaptic vesicle reclustering after endocytosis | Q35058315 | ||
| α-Synuclein and ALPS motifs are membrane curvature sensors whose contrasting chemistry mediates selective vesicle binding. | Q35102466 | ||
| Direct observation of the three regions in α-synuclein that determine its membrane-bound behaviour | Q35175448 | ||
| Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death | Q35484581 | ||
| Total and Proteinase K-Resistant α-Synuclein Levels in Erythrocytes, Determined by their Ability to Bind Phospholipids, Associate with Parkinson's Disease | Q35726772 | ||
| Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice | Q35946149 | ||
| KTKEGV repeat motifs are key mediators of normal α-synuclein tetramerization: Their mutation causes excess monomers and neurotoxicity | Q35946269 | ||
| α-Synuclein - Regulator of Exocytosis, Endocytosis, or Both? | Q36297384 | ||
| Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants | Q36298004 | ||
| Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading | Q36659034 | ||
| Structural and functional properties of prefibrillar α-synuclein oligomers | Q36796130 | ||
| GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein | Q36825286 | ||
| NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded | Q36830682 | ||
| The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates | Q37003482 | ||
| Mapping the subcellular distribution of α-synuclein in neurons using genetically encoded probes for correlated light and electron microscopy: implications for Parkinson's disease pathogenesis | Q37012885 | ||
| Role of Lipids in Brain Injury and Diseases | Q37051065 | ||
| A small-angle X-ray scattering study of alpha-synuclein from human red blood cells | Q37137415 | ||
| Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. | Q37153744 | ||
| Direct detection of alpha synuclein oligomers in vivo | Q37180232 | ||
| Multiple tight phospholipid-binding modes of alpha-synuclein revealed by solution NMR spectroscopy | Q37258811 | ||
| Structural basis of synaptic vesicle assembly promoted by α-synuclein | Q37273635 | ||
| Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells | Q37446544 | ||
| Comprehensive Proteomic Analysis of Human Erythropoiesis | Q37611376 | ||
| Trifunctional lipid probes for comprehensive studies of single lipid species in living cells | Q37658916 | ||
| Non-vesicular lipid transport by lipid-transfer proteins and beyond | Q37786206 | ||
| The Lewy body in Parkinson's disease and related neurodegenerative disorders | Q38012653 | ||
| Fat & fabulous: bifunctional lipids in the spotlight. | Q38179799 | ||
| Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry | Q38194196 | ||
| Oligomeropathies and pathogenesis of Alzheimer and Parkinson's diseases. | Q38794219 | ||
| Structural disorder of monomeric α-synuclein persists in mammalian cells. | Q38799574 | ||
| Lipidomics: Techniques, Applications, and Outcomes Related to Biomedical Sciences | Q38803730 | ||
| The Role of Lipids Interacting with α-Synuclein in the Pathogenesis of Parkinson's Disease | Q39410832 | ||
| Physico-Pathologic Mechanisms Involved in Neurodegeneration: Misfolded Protein-Plasma Membrane Interactions | Q39418514 | ||
| Alpha-synuclein binds large unilamellar vesicles as an extended helix | Q39575705 | ||
| Modeling Parkinson's disease pathology by combination of fibril seeds and α-synuclein overexpression in the rat brain | Q40044736 | ||
| Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein | Q40763309 | ||
| Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation | Q41065976 | ||
| Semisynthetic and in Vitro Phosphorylation of Alpha-Synuclein at Y39 Promotes Functional Partly Helical Membrane-Bound States Resembling Those Induced by PD Mutations | Q41728474 | ||
| α-Synuclein promotes dilation of the exocytotic fusion pore. | Q41757696 | ||
| α-Synuclein inhibits intersynaptic vesicle mobility and maintains recycling-pool homeostasis | Q41901772 | ||
| The influence of vesicle size and composition on alpha-synuclein structure and stability | Q42141525 | ||
| α-Synuclein senses lipid packing defects and induces lateral expansion of lipids leading to membrane remodeling | Q42184977 | ||
| Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth | Q42375123 | ||
| α-synuclein multimers cluster synaptic vesicles and attenuate recycling | Q42548002 | ||
| Membrane-bound alpha-synuclein forms an extended helix: long-distance pulsed ESR measurements using vesicles, bicelles, and rodlike micelles | Q43198829 | ||
| Sphingomyelin in Lewy inclusion bodies in Parkinson's disease | Q43441611 | ||
| P304 | page(s) | 23 | |
| P577 | publication date | 2019-11-12 | |
| P1433 | published in | NPJ Parkinson's disease | Q27727151 |
| P1476 | title | Endogenous alpha-synuclein monomers, oligomers and resulting pathology: let's talk about the lipids in the room | |
| P478 | volume | 5 |
| Q89511152 | Cerium Oxide Nanoparticles Rescue α-Synuclein-Induced Toxicity in a Yeast Model of Parkinson's Disease | cites work | P2860 |
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