Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial

scientific article published on 08 February 2019

Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1470-2045(18)30859-3
P698PubMed publication ID30745090

P50authorBrian SlomovitzQ123915583
Morten Mau-SorensenQ47424313
James SpicerQ86599148
P2093author name stringJohann S de Bono
Ulrik Lassen
Joo Ern Ang
Nicole Concin
David S Hong
Ruth Plummer
Hendrik-Tobias Arkenau
Jean-Pascal Machiels
Jeffrey Yachnin
Dorte Nielsen
Reshma A Rangwala
Srinivas Ghatta
Dearbhaile Collins
Fiona C Thistlethwaite
Emma Dean
Kristian Windfeld
Martin David Forster
Robert Hugh Jones
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Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factorQ33938673
hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma.Q34253625
Tissue factor, blood coagulation, and beyond: an overviewQ35222618
Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factorQ36972097
Five-year survival and durability results of brentuximab vedotin in patients with relapsed or refractory Hodgkin lymphomaQ37279128
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Tissue factor and VEGF expression in prostate carcinoma: a tissue microarray studyQ38422779
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Effects of antibody, drug and linker on the preclinical and clinical toxicities of antibody-drug conjugatesQ38798481
High turnover of tissue factor enables efficient intracellular delivery of antibody-drug conjugatesQ38905336
Prognostic significance of tissue factor in pancreatic ductal adenocarcinomaQ40438100
Phase I Study of DMOT4039A, an Antibody-Drug Conjugate Targeting Mesothelin, in Patients with Unresectable Pancreatic or Platinum-Resistant Ovarian Cancer.Q40943118
Tissue factor expression and prognosis in patients with metastatic prostate cancerQ44686290
Tumour expresion of tissue factor and tissue factor pathway inhibitor in ovarian cancer- relationship with venous thrombosis riskQ45150436
An antibody-drug conjugate that targets tissue factor exhibits potent therapeutic activity against a broad range of solid tumorsQ45231931
Isolation, Detection, and Antigen-Based Profiling of Circulating Tumor Cells Using a Size-Dictated Immunocapture Chip.Q47202441
Immunolocalisation of tissue factor in esophageal cancer is correlated with intratumoral angiogenesis and prognosis of the patientQ47845503
Tissue-factor expression in human non-small-cell lung carcinoma measured by immunohistochemistry: correlation between tissue factor and angiogenesis.Q54145263
Tissue factor expression correlates with disease-specific survival in patients with node-negative muscle-invasive bladder cancerQ80145540
A phase I weekly dosing study of brentuximab vedotin in patients with relapsed/refractory CD30-positive hematologic malignanciesQ82489143
Expression of tissue factor and heparanase in endometrial clear cell carcinoma: possible role for tissue factor in thromboembolic eventsQ83780867
P433issue3
P921main subjectphase I clinical trialQ5452194
multicenter clinical trialQ6934595
P304page(s)383-393
P577publication date2019-02-08
P1433published inLancet Oncology CommissionQ13747613
P1476titleTisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial
P478volume20

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cites work (P2860)
Q90681595Encyclopedic tumor analysis for guiding treatment of advanced, broadly refractory cancers: results from the RESILIENT trial
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Q92366436Precision medicine for human cancers with Notch signaling dysregulation (Review)
Q98164379Targeted therapies in gynecological cancers: a comprehensive review of clinical evidence
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Q89767304Tissue factor as a new target for CAR-NK cell immunotherapy of triple-negative breast cancer
Q90170947Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial-mesenchymal transitions and facilitates early metastasis
Q90325608[Monoclonal antibodies]

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