scholarly article | Q13442814 |
P50 | author | Masatoshi Miyamoto | Q88707494 |
Akio Kihara | Q42656232 | ||
Takayuki Sassa | Q86708529 | ||
Megumi Sawai | Q88707490 | ||
P2860 | cites work | Mammalian wax biosynthesis. I. Identification of two fatty acyl-Coenzyme A reductases with different substrate specificities and tissue distributions | Q24298012 |
ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis | Q24302388 | ||
Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily | Q28118125 | ||
Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids | Q28592642 | ||
Lipidomics of human Meibomian gland secretions: Chemistry, biophysics, and physiological role of Meibomian lipids | Q28743677 | ||
A role for ELOVL4 in the mouse meibomian gland and sebocyte cell biology | Q33558508 | ||
Meibum lipid composition in Asians with dry eye disease | Q34063529 | ||
Estimated Prevalence and Incidence of Dry Eye Disease Based on Coding Analysis of a Large, All-age United States Health Care System | Q91354085 | ||
Severe Skin Permeability Barrier Dysfunction in Knockout Mice Deficient in a Fatty Acid ω-Hydroxylase Crucial to Acylceramide Production | Q92253364 | ||
Biosynthesis of the anti-lipid-microdomain sphingoid base 4,14-sphingadiene by the ceramide desaturase FADS3 | Q92511300 | ||
Skin permeability barrier formation by the ichthyosis-causative gene FATP4 through formation of the barrier lipid ω-O-acylceramide | Q92889669 | ||
Short Tear Film Breakup Time-Type Dry Eye | Q93343199 | ||
Essential role of the cytochrome P450 CYP4F22 in the production of acylceramide, the key lipid for skin permeability barrier formation | Q34479815 | ||
Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3. | Q34488090 | ||
The international workshop on meibomian gland dysfunction: report of the subcommittee on anatomy, physiology, and pathophysiology of the meibomian gland | Q34769303 | ||
Loss of functional ELOVL4 depletes very long-chain fatty acids (> or =C28) and the unique omega-O-acylceramides in skin leading to neonatal death | Q35729216 | ||
Distribution of mucins at the ocular surface | Q35755130 | ||
Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: evidence suggesting multiple cholesterol esterification enzymes in mammals | Q35941759 | ||
Toward an animal model of the human tear film: biochemical comparison of the mouse, canine, rabbit, and human meibomian lipidomes | Q36302985 | ||
Laboratory findings in tear fluid analysis | Q36413771 | ||
Tissue- and stratum-specific expression of the human involucrin promoter in transgenic mice | Q36643505 | ||
Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production | Q36978366 | ||
Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometry | Q37120206 | ||
Etiology, prevalence, and treatment of dry eye disease | Q37288773 | ||
Human tear film and meibum. Very long chain wax esters and (O-acyl)-omega-hydroxy fatty acids of meibum | Q37430622 | ||
The international workshop on meibomian gland dysfunction: report of the subcommittee on tear film lipids and lipid-protein interactions in health and disease. | Q37859544 | ||
Very long-chain fatty acids: elongation, physiology and related disorders | Q38043980 | ||
Tear film lipids | Q38114679 | ||
Four characteristics and a model of an effective tear film lipid layer (TFLL). | Q38151226 | ||
TFOS DEWS II Tear Film Report. | Q38652990 | ||
Meibomian glands, meibum, and meibogenesis | Q38697707 | ||
Tear film lipid layer: A molecular level view | Q38742772 | ||
Synthesis and degradation pathways, functions, and pathology of ceramides and epidermal acylceramides. | Q38815727 | ||
Comparative chemistry of sebum | Q39880644 | ||
Report of the National Eye Institute/Industry workshop on Clinical Trials in Dry Eyes. | Q40948258 | ||
Phytosphingosine degradation pathway includes fatty acid α-oxidation reactions in the endoplasmic reticulum. | Q41677978 | ||
PNPLA1 is a transacylase essential for the generation of the skin barrier lipid ω-O-acylceramide. | Q41898000 | ||
Evaluation of the clinical course of dry eye syndrome | Q44616226 | ||
Involucrin expression in the corneal epithelium: an essential role for Sp1 transcription factors | Q46670198 | ||
Mouse sphingosine kinase isoforms SPHK1a and SPHK1b differ in enzymatic traits including stability, localization, modification, and oligomerization | Q46861688 | ||
TFOS DEWS II Report Executive Summary. | Q46919939 | ||
The contribution of lipid layer movement to tear film thinning and breakup. | Q51851737 | ||
Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice. | Q52688144 | ||
The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function | Q57043840 | ||
Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (-acyl)-ω-hydroxy fatty acids | Q57172762 | ||
The contribution of meibomian disease to dry eye | Q57648466 | ||
Spontaneous Eye Blink Patterns in Dry Eye: Clinical Correlations | Q58125180 | ||
Hydrodynamics of blinking. In vitro study of the interaction of the superficial oily layer and the tears | Q71221428 | ||
Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia | Q73703942 | ||
P921 | main subject | eye disease | Q3041498 |
P577 | publication date | 2020-04-07 | |
P1433 | published in | eLife | Q2000008 |
P1476 | title | Lipid polarity gradient formed by ω-hydroxy lipids in tear film prevents dry eye disease | |
P478 | volume | 9 |
Q98773073 | Deficiency in Acyl-CoA:Wax Alcohol Acyltransferase 2 causes evaporative dry eye disease by abolishing biosynthesis of wax esters |
Q112581930 | Human Meibum and Tear Film Derived (O-Acyl)-Omega-Hydroxy Fatty Acids as Biomarkers of Tear Film Dynamics in Meibomian Gland Dysfunction and Dry Eye Disease |
Q114873673 | Identification of new Omega-3 very long chain poly-unsaturated fatty acids in meibomian gland secretions |
Q96613585 | Interactions of polar lipids with cholesteryl ester multilayers elucidate tear film lipid layer structure |
Q102058589 | Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis |
Q100697853 | Production of branched-chain very-long-chain fatty acids by fatty acid elongases and their tissue distribution in mammals |
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