Nanoparticle Delivery and Tumor Vascular Normalization: The Chicken or The Egg?

scientific article published on 12 November 2019

Nanoparticle Delivery and Tumor Vascular Normalization: The Chicken or The Egg? is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.3389/FONC.2019.01227
P932PMC publication ID6863425
P698PubMed publication ID31799190

P2093author name stringConstantinos M Mikelis
George Mattheolabakis
P2860cites workThe miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2Q24608778
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2Q24646996
Nivolumab plus ipilimumab in advanced melanomaQ27852310
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1Q27861068
Sorafenib in advanced hepatocellular carcinomaQ27861075
Molecular mechanisms and clinical applications of angiogenesisQ29547314
Angiogenesis: an organizing principle for drug discovery?Q29614538
Nanocarriers as an emerging platform for cancer therapyQ29616699
Sonoporation enhances liposome accumulation and penetration in tumors with low EPR.Q30358121
Antiangiogenesis strategies revisited: from starving tumors to alleviating hypoxiaQ30399006
Nanoparticle uptake in tumors is mediated by the interplay of vascular and collagen density with interstitial pressure.Q30443689
Solid lipid nanoparticles: a modern formulation approach in drug delivery systemQ30481400
Pazopanib versus sunitinib in metastatic renal-cell carcinomaQ33409916
Gold nanoparticles attenuate metastasis by tumor vasculature normalization and epithelial-mesenchymal transition inhibitionQ33650400
Effect of aerobic exercise on tumor physiology in an animal model of human breast cancerQ33656658
Anti-angiogenic therapy for cancer: current progress, unresolved questions and future directionsQ33770680
Vascular normalization in orthotopic glioblastoma following intravenous treatment with lipid-based nanoparticulate formulations of irinotecan (Irinophore C™), doxorubicin (Caelyx®) or vincristineQ33866374
Remodeling Tumor Vasculature to Enhance Delivery of Intermediate-Sized Nanoparticles.Q50951676
Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes.Q53006384
Non-Viral Based miR Delivery and Recent Developments.Q54231141
Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges.Q55190117
Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200Q56679480
Ipilimumab in combination with nivolumab for the treatment of renal cell carcinomaQ56889461
Emerging applications of upconverting nanoparticles in intestinal infection and colorectal cancerQ64235025
Therapeutic Remodeling of the Tumor Microenvironment Enhances Nanoparticle DeliveryQ64239906
Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targetingQ83165400
Biocompatible and biodegradable nanoparticles for enhancement of anti-cancer activities of phytochemicalsQ86291066
Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppressionQ88873222
Chloroquine in combination with aptamer-modified nanocomplexes for tumor vessel normalization and efficient erlotinib/Survivin shRNA co-delivery to overcome drug resistance in EGFR-mutated non-small cell lung cancerQ89361908
Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatmentQ91051056
Attempts to strengthen and simplify the tumor vascular normalization strategy using tumor vessel normalization promoting nanomedicinesQ91069512
Targeted Nanodelivery of Drugs and DiagnosticsQ33900258
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology.Q34447986
To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?Q34545282
Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cellsQ34984247
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent mannerQ36016318
Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects.Q36301173
Modulation of murine breast tumor vascularity, hypoxia and chemotherapeutic response by exercise.Q36770262
OCEANS: a randomized, double-blind, placebo-controlled phase III trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent epithelial ovarian, primary peritoneal, or fallopian tube cancerQ36822179
Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticlesQ36833069
Gold Nanoparticle-Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer TherapyQ37137190
Principles of nanoparticle design for overcoming biological barriers to drug deliveryQ37162182
Improved tumor oxygenation and survival in glioblastoma patients who show increased blood perfusion after cediranib and chemoradiation.Q37340643
Exploiting macrophages as targeted carrier to guide nanoparticles into gliomaQ37392913
Tumour angiogenesis regulation by the miR-200 familyQ37523569
Optimization of the tumor microenvironment and nanomedicine properties simultaneously to improve tumor therapyQ37641818
Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy.Q37662252
Modulation of blood flow, hypoxia, and vascular function in orthotopic prostate tumors during exercise.Q37696695
Nivolumab in renal cell carcinoma: latest evidence and clinical potentialQ37698611
Growing tumor vessels: more than one way to skin a cat - implications for angiogenesis targeted cancer therapies.Q37871679
Principles and mechanisms of vessel normalization for cancer and other angiogenic diseasesQ37883025
Doxil®--the first FDA-approved nano-drug: lessons learnedQ38000876
Nanodelivery strategies in cancer chemotherapy: biological rationale and pharmaceutical perspectivesQ38059498
The discovery and development of cyclooxygenase-2 inhibitors as potential anticancer therapiesQ38183889
Pembrolizumab: first global approvalQ38261580
Monitoring immune-checkpoint blockade: response evaluation and biomarker developmentQ38666241
Actively Targeted Nanoparticles for Drug Delivery to TumorQ38849488
Exploring Novel Methods for Modulating Tumor Blood Vessels in Cancer TreatmentQ39003100
Tumor angiogenesis and vascular normalization: alternative therapeutic targetsQ39403862
Liposome: classification, preparation, and applicationsQ41049173
Celecoxib normalizes the tumor microenvironment and enhances small nanotherapeutics delivery to A549 tumors in nude mice.Q41565207
The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanismsQ41577994
Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical modelQ42573981
Quantifying the effects of antiangiogenic and chemotherapy drug combinations on drug delivery and treatment efficacy.Q42708321
Toxicity of a soybean oil emulsion on human lymphocytes and neutrophilsQ46976057
Nanoparticle targeting to the endothelium during normothermic machine perfusion of human kidneysQ47175243
Normalizing Tumor Vessels To Increase the Enzyme-Induced Retention and Targeting of Gold Nanoparticle for Breast Cancer Imaging and Treatment.Q48168833
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectnanoparticleQ61231
P304page(s)1227
P577publication date2019-11-12
P1433published inFrontiers in OncologyQ26839986
P1476titleNanoparticle Delivery and Tumor Vascular Normalization: The Chicken or The Egg?
P478volume9

Reverse relations

cites work (P2860)
Q92924413Low Dose of Penfluridol Inhibits VEGF-Induced Angiogenesis
Q99632062Modulating barriers of tumor microenvironment through nanocarrier systems for improved cancer immunotherapy: a review of current status and future perspective

Search more.