Factors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening

scientific article published on 04 December 2019

Factors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S40246-019-0244-0
P932PMC publication ID6894209
P698PubMed publication ID31801621

P2093author name stringYi Li
Dongmei Wang
Fangfang Guo
Aihua Yin
Yiming Qi
Yaping Hou
Haishan Peng
Jiexia Yang
Yixia Wang
Xiaohui Luo
P2860cites workMicrofluidics digital PCR reveals a higher than expected fraction of fetal DNA in maternal plasmaQ33360224
Noninvasive prenatal diagnosis of common aneuploidies by semiconductor sequencingQ33665399
Genome-wide fetal aneuploidy detection by maternal plasma DNA sequencingQ34256640
Gestational age and maternal weight effects on fetal cell-free DNA in maternal plasmaQ34336915
Rapid clearance of fetal DNA from maternal plasmaQ34388637
Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity studyQ34482155
High-throughput massively parallel sequencing for fetal aneuploidy detection from maternal plasmaQ34618332
A multifactorial relationship exists between total circulating cell-free DNA levels and maternal BMIQ36205202
Noninvasive detection of fetal subchromosomal abnormalities by semiconductor sequencing of maternal plasma DNAQ36332125
Increased death of adipose cells, a path to release cell-free DNA into systemic circulation of obese womenQ36354286
Non-invasive prenatal testing for Down syndromeQ38161185
Cell-Free DNA Screening: Complexities and Challenges of Clinical Implementation.Q38928166
Noninvasive prenatal testing for aneuploidy using cell-free DNA - New implications for maternal health.Q39004076
Size distributions of maternal and fetal DNA in maternal plasma.Q47432593
Cell-Free DNA Screening for Aneuploidy and Microdeletion SyndromesQ50083914
Cell-Free DNA Analysis of Targeted Genomic Regions in Maternal Plasma for Non-Invasive Prenatal Testing of Trisomy 21, Trisomy 18, Trisomy 13, and Fetal Sex.Q50658711
Determination of fetal DNA fraction from the plasma of pregnant women using sequence read counts.Q51025463
Circulating fetal cell-free DNA fractions differ in autosomal aneuploidies and monosomy X.Q51163080
Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18.Q51349861
Free fetal DNA in maternal plasma in anembryonic pregnancies: confirmation that the origin is the trophoblast.Q51767524
Early detection of cell-free fetal DNA in maternal plasma.Q53576548
The impact of maternal plasma DNA fetal fraction on next generation sequencing tests for common fetal aneuploidies.Q54708648
Presence of fetal DNA in maternal plasma and serumQ57075132
Fetal fraction in maternal plasma cell-free DNA at 11-13 weeks' gestation: relation to maternal and fetal characteristicsQ61847812
Fetal Fraction in Maternal Plasma Cell-Free DNA at 11–13 Weeks’ Gestation: Effect of Maternal and Fetal FactorsQ61847823
The Quest for Accurate Measurement of Fetal DNA in Maternal PlasmaQ85023769
Factors affecting levels of circulating cell-free fetal DNA in maternal plasma and their implications for noninvasive prenatal testingQ85218234
Committee Opinion No. 545: Noninvasive prenatal testing for fetal aneuploidyQ85495453
Screening for trisomies 21, 18 and 13 by cell-free DNA analysis of maternal blood at 10-11 weeks' gestation and the combined test at 11-13 weeksQ85632797
Screening for trisomies by cell-free DNA testing of maternal blood: consequences of a failed resultQ87035902
Non-Invasive Prenatal Testing (NIPT) in pregnancies with trisomy 21, 18 and 13 performed in a public setting - factors of importance for correct interpretation of resultsQ88873306
P433issue1
P921main subjectstatisticsQ12483
P304page(s)62
P577publication date2019-12-04
P1433published inHuman genomicsQ26842690
P1476titleFactors affecting cell-free DNA fetal fraction: statistical analysis of 13,661 maternal plasmas for non-invasive prenatal screening
P478volume13

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