| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Christof Burger | |
| Frank A Schildberg | |||
| Dieter C Wirtz | |||
| Zachary R Barbati | |||
| Jil M Jubel | |||
| P2860 | cites work | Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death | Q24293504 |
| CTLA-4 and PD-1 receptors inhibit T-cell activation by distinct mechanisms | Q24534904 | ||
| Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade | Q24535835 | ||
| X-Linked syndrome of polyendocrinopathy, immune dysfunction, and diarrhea maps to Xp11.23-Xq13.3. | Q24539046 | ||
| The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells | Q24655751 | ||
| Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation | Q24675931 | ||
| Role of Tim-3 in hepatitis B virus infection: An overview | Q26768530 | ||
| Molecular and cellular insights into T cell exhaustion | Q26800047 | ||
| Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade | Q27487939 | ||
| Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization | Q27488289 | ||
| High-programmed death-1 levels on hepatitis C virus-specific T cells during acute infection are associated with viral persistence and require preservation of cognate antigen during chronic infection | Q27490345 | ||
| Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C | Q27490355 | ||
| OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells | Q28188488 | ||
| Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice | Q28201627 | ||
| Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses | Q28202175 | ||
| PD-L2 is a second ligand for PD-1 and inhibits T cell activation | Q28202471 | ||
| Expression of programmed death 1 ligands by murine T cells and APC | Q28214264 | ||
| Restoring function in exhausted CD8 T cells during chronic viral infection | Q28289222 | ||
| Structure and chromosomal localization of the human PD-1 gene (PDCD1) | Q28307081 | ||
| PD-L1 Blockade Differentially Impacts Regulatory T Cells from HIV-Infected Individuals Depending on Plasma Viremia | Q28551329 | ||
| Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration | Q29547429 | ||
| Regulatory T cells and immune tolerance | Q29616864 | ||
| PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression | Q29618956 | ||
| PD-L1 regulates the development, maintenance, and function of induced regulatory T cells | Q30080038 | ||
| Reinventing HCV Treatment: Past and Future Perspectives | Q30241881 | ||
| Programmed cell death 1 forms negative costimulatory microclusters that directly inhibit T cell receptor signaling by recruiting phosphatase SHP2. | Q30515733 | ||
| Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation | Q33604835 | ||
| Proportions of circulating follicular helper T cells are reduced and correlate with memory B cells in HIV-infected children. | Q33605792 | ||
| CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition | Q33762255 | ||
| Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection | Q33817504 | ||
| Role of PD-1 in regulating acute infections. | Q34001843 | ||
| Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis | Q34067889 | ||
| Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection | Q34239730 | ||
| SHP-1 and SHP-2 associate with immunoreceptor tyrosine-based switch motif of programmed death 1 upon primary human T cell stimulation, but only receptor ligation prevents T cell activation | Q34331884 | ||
| PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta | Q34347206 | ||
| Unique human immune signature of Ebola virus disease in Guinea | Q34525050 | ||
| Cutting edge: Direct recognition of infected cells by CD4 T cells is required for control of intracellular Mycobacterium tuberculosis in vivo | Q42256751 | ||
| In vivo blockade of the PD-1 receptor suppresses HIV-1 viral loads and improves CD4+ T cell levels in humanized mice | Q42427922 | ||
| Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection | Q42797242 | ||
| Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B. | Q45395326 | ||
| Human immunodeficiency virus-driven expansion of CD4+CD25+ regulatory T cells, which suppress HIV-specific CD4 T-cell responses in HIV-infected patients | Q45609885 | ||
| The diverse functions of the PD1 inhibitory pathway | Q47678849 | ||
| Structural and functional analysis of the costimulatory receptor programmed death-1. | Q47926421 | ||
| Inhibitors of the PD-1 Pathway in Tumor Therapy | Q48293633 | ||
| Relationship of CD4+CD25+ regulatory T cells to immune status in HIV-infected patients. | Q53674954 | ||
| PDL-1 blockade prevents T cell exhaustion, inhibits autophagy, and promotes clearance of Leishmania donovani. | Q53696568 | ||
| Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages. | Q54204346 | ||
| PD-L1 expression on human ocular cells and its possible role in regulating immune-mediated ocular inflammation. | Q54515974 | ||
| Programmed Cell Death Protein 1-PDL1 Interaction Prevents Heart Damage in Chronic Trypanosoma cruzi Infection. | Q55018150 | ||
| Induction of CTLA-4-mediated anergy contributes to persistent colonization in the murine model of gastric Helicobacter pylori infection | Q56902208 | ||
| Recent advances in immunotherapies: from infection and autoimmunity, to cancer, and back again | Q58087985 | ||
| A Rare Case of Pembrolizumab-Induced Reactivation of Hepatitis B | Q58699463 | ||
| Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B | Q58802765 | ||
| PD-1 blockade potentiates HIV latency reversal ex vivo in CD4 T cells from ART-suppressed individuals | Q64252705 | ||
| Increased Programmed Death-Ligand 1 is an Early Epithelial Cell Response to Helicobacter pylori Infection | Q64256264 | ||
| Dendritic Cell PD-L1 Limits Autoimmunity and Follicular T Cell Differentiation and Function. | Q64991932 | ||
| Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction | Q80641790 | ||
| A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment | Q80726091 | ||
| Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis | Q84255932 | ||
| PD-1 and PD-L1 regulate cellular immunity in canine visceral leishmaniasis | Q91315784 | ||
| The PD-1/PD-L1 Axis and Virus Infections: A Delicate Balance | Q91534182 | ||
| CD4+ T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B | Q92480011 | ||
| Different Expression Characteristics of LAG3 and PD-1 in Sepsis and Their Synergistic Effect on T Cell Exhaustion: A New Strategy for Immune Checkpoint Blockade | Q92800347 | ||
| Expression of programmed cell death protein 1 and T-cell immunoglobulin- and mucin-domain-containing molecule-3 on peripheral blood CD4+CD8+ double positive T cells in patients with chronic hepatitis C virus infection and in subjects who spontaneous | Q93019262 | ||
| Reactivation of tuberculosis in cancer patients following administration of immune checkpoint inhibitors: current evidence and clinical practice recommendations | Q93103947 | ||
| Checkpoint Inhibition and Infectious Diseases: A Good Thing? | Q93169007 | ||
| The CD28 signaling pathway regulates glucose metabolism | Q34525357 | ||
| Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction | Q34570127 | ||
| PD-1 upregulation is associated with HBV-specific T cell dysfunction in chronic hepatitis B patients | Q34583020 | ||
| Enhancing SIV-specific immunity in vivo by PD-1 blockade | Q34601856 | ||
| PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis | Q34605998 | ||
| PD-1 on dendritic cells impedes innate immunity against bacterial infection | Q34606110 | ||
| A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection | Q34744674 | ||
| Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection. | Q34891171 | ||
| Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1-PDL-1 blockade | Q35021925 | ||
| PD-1 blockade in chronically HIV-1-infected humanized mice suppresses viral loads | Q35035610 | ||
| B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade | Q35073276 | ||
| PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism | Q35118078 | ||
| Expression of CD25(high) regulatory T cells and PD-1 in gastric infiltrating CD4(+) T lymphocytes in patients with Helicobacter pylori infection | Q35138630 | ||
| Responsiveness of HIV-specific CD4 T cells to PD-1 blockade | Q35140996 | ||
| Costimulation of T cells by OX40, 4-1BB, and CD27. | Q35145627 | ||
| Treatment of hepatitis C: a systematic review | Q35223637 | ||
| PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation | Q35311785 | ||
| Helicobacter pylori eradication cannot reduce the risk of gastric cancer in patients with intestinal metaplasia and dysplasia: evidence from a meta-analysis | Q35546981 | ||
| Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients. | Q35559497 | ||
| PD-L1 blockade improves survival in experimental sepsis by inhibiting lymphocyte apoptosis and reversing monocyte dysfunction | Q35561405 | ||
| Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells | Q35824223 | ||
| Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination | Q35857708 | ||
| The role of coinhibitory signaling pathways in transplantation and tolerance | Q35928357 | ||
| Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy | Q35984560 | ||
| Programmed death-1 controls T cell survival by regulating oxidative metabolism. | Q36036001 | ||
| The late phase of sepsis is characterized by an increased microbiological burden and death rate | Q36070469 | ||
| CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART. | Q36077348 | ||
| Viral acute lower respiratory infections impair CD8+ T cells through PD-1 | Q36129102 | ||
| T cells and viral persistence: lessons from diverse infections | Q36238129 | ||
| T-cell exhaustion in the tumor microenvironment | Q36347369 | ||
| A critical role for the programmed death ligand 1 in fetomaternal tolerance | Q36403162 | ||
| The immune response during hepatitis B virus infection | Q36475911 | ||
| Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice. | Q36478253 | ||
| Phenotypic Characteristics of PD-1 and CTLA-4 Expression in Symptomatic Acute Hepatitis A. | Q36658449 | ||
| The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection | Q36737159 | ||
| Longitudinal characterization of dysfunctional T cell-activation during human acute Ebola infection. | Q36775011 | ||
| Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease | Q36919711 | ||
| Human CD4+ CD25+ regulatory T cells control T-cell responses to human immunodeficiency virus and cytomegalovirus antigens | Q36954734 | ||
| Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family | Q36998864 | ||
| Parasite-derived arginase influences secondary anti-Leishmania immunity by regulating programmed cell death-1-mediated CD4+ T cell exhaustion. | Q37080079 | ||
| CD28 family of receptors on T cells in chronic HBV infection: Expression characteristics, clinical significance and correlations with PD-1 blockade | Q37083009 | ||
| Negative T-cell costimulatory pathways: their role in regulating alloimmune responses | Q37236953 | ||
| Programmed death-1 expression is associated with the disease status in hepatitis B virus infection | Q37316915 | ||
| Local blockade of epithelial PDL-1 in the airways enhances T cell function and viral clearance during influenza virus infection | Q37336527 | ||
| Inadequate T follicular cell help impairs B cell immunity during HIV infection. | Q37349638 | ||
| Programmed death 1 regulates development of central memory CD8 T cells after acute viral infection | Q37372772 | ||
| Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cells | Q37483184 | ||
| Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function | Q37494790 | ||
| Role of PD-L1/PD-1 in the immune response to respiratory viral infections. | Q37979615 | ||
| Coinhibitory Pathways in Immunotherapy for Cancer | Q38755150 | ||
| Immune checkpoints and their inhibition in cancer and infectious diseases. | Q38845026 | ||
| IFN-α directly promotes programmed cell death-1 transcription and limits the duration of T cell-mediated immunity | Q39603416 | ||
| Increased programmed death-ligand-1 expression in human gastric epithelial cells in Helicobacter pylori infection | Q39677907 | ||
| Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis. | Q39980573 | ||
| Differential Inhibitory Receptor Expression on T Cells Delineates Functional Capacities in Chronic Viral Infection | Q40042407 | ||
| Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection | Q40313152 | ||
| The characteristic profiles of PD-1 and PD-L1 expressions and dynamic changes during treatment in active tuberculosis. | Q40444268 | ||
| Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4(+) T Cell Immunity | Q40572670 | ||
| Multiple Inhibitory Pathways Contribute to Lung CD8+ T Cell Impairment and Protect against Immunopathology during Acute Viral Respiratory Infection | Q40646507 | ||
| Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection. | Q40695934 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P304 | page(s) | 487 | |
| P577 | publication date | 2020-03-24 | |
| P1433 | published in | Frontiers in Immunology | Q27723748 |
| P1476 | title | The Role of PD-1 in Acute and Chronic Infection | |
| P478 | volume | 11 |
| Q99571941 | Impaired Cytotoxic CD8+ T Cell Response in Elderly COVID-19 Patients | cites work | P2860 |
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