Comprehensive manipulation of glycosylation profiles across development scales

scientific article published on 22 October 2018

Comprehensive manipulation of glycosylation profiles across development scales is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1080/19420862.2018.1527665
P932PMC publication ID6380396
P698PubMed publication ID30252592

P50authorElisa ClarkQ90662826
Sven LoebrichQ91723112
P2093author name stringThomas Ryll
Stefani Takahashi
Anna Brousseau
Kristina Ladd
Robert Herbst
Seth Kitchener
P2860cites workGlycoprofiling effects of media additives on IgG produced by CHO cells in fed-batch bioreactors.Q51741789
Modulation of mAb quality attributes using microliter scale fed-batch cultures.Q51749017
The effect of the removal of sialic acid, galactose and total carbohydrate on the functional activity of Campath-1HQ71108219
Improvement of interferon-gamma sialylation in Chinese hamster ovary cell culture by feeding of N-acetylmannosamineQ28140074
Depletion of manganese within the secretory pathway inhibits O-linked glycosylation in mammalian cellsQ30420604
Lack of fucose on human IgG1 N-linked oligosaccharide improves binding to human Fcgamma RIII and antibody-dependent cellular toxicityQ30835165
High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humansQ31004131
Glycosylation of therapeutic proteins: an effective strategy to optimize efficacyQ33586660
Effect of altered CH2-associated carbohydrate structure on the functional properties and in vivo fate of chimeric mouse-human immunoglobulin G1.Q36363690
Increased serum clearance of oligomannose species present on a human IgG1 moleculeQ36402812
Enhanced recombinant M-CSF production in CHO cells by glycerol addition: model and validationQ36495607
Optimisation of the cellular metabolism of glycosylation for recombinant proteins produced by Mammalian cell systemsQ37323542
Optimal and consistent protein glycosylation in mammalian cell cultureQ37506963
Recent advances in the understanding of biological implications and modulation methodologies of monoclonal antibody N-linked high mannose glycansQ38224264
Comparison of biological activity among nonfucosylated therapeutic IgG1 antibodies with three different N-linked Fc oligosaccharides: the high-mannose, hybrid, and complex typesQ38308978
Effect of C2-associated carbohydrate structure on Ig effector function: studies with chimeric mouse-human IgG1 antibodies in glycosylation mutants of Chinese hamster ovary cells.Q38338731
Antibody-dependent cytotoxicity mediated by natural killer cells is enhanced by castanospermine-induced alterations of IgG glycosylationQ38342853
Tailoring recombinant protein quality by rational media designQ38416739
N-Glycosylation Design and Control of Therapeutic Monoclonal AntibodiesQ38789301
Screening and assessment of performance and molecule quality attributes of industrial cell lines across different fed-batch systemsQ38826159
Impact of cell culture on recombinant monoclonal antibody product heterogeneityQ38907094
CHO cell line specific prediction and control of recombinant monoclonal antibody N-glycosylationQ39143876
Fucose content of monoclonal antibodies can be controlled by culture medium osmolality for high antibody-dependent cellular cytotoxicityQ39484103
Modulation of antibody galactosylation through feeding of uridine, manganese chloride, and galactoseQ39590627
Characterizing the effect of multiple Fc glycan attributes on the effector functions and FcγRIIIa receptor binding activity of an IgG1 antibodyQ39782184
Rapid production of recombinant human IgG With improved ADCC effector function in a transient expression systemQ39801809
Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions.Q40420472
The absence of fucose but not the presence of galactose or bisecting N-acetylglucosamine of human IgG1 complex-type oligosaccharides shows the critical role of enhancing antibody-dependent cellular cytotoxicityQ40690773
Biochemistry of growth inhibition by ammonium ions in mammalian cellsQ41460725
Controllability analysis of protein glycosylation in CHO cellsQ41909859
Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycomeQ42321222
An investigation of intracellular glycosylation activities in CHO cells: effects of nucleotide sugar precursor feedingQ43053168
Metabolic control of recombinant protein N-glycan processing in NS0 and CHO cellsQ43547015
Metabolic control of recombinant monoclonal antibody N-glycosylation in GS-NS0 cellsQ43728275
Effects of ammonia and glucosamine on the heterogeneity of erythropoietin glycoforms.Q43873679
Glycosylation by Chinese hamster ovary cells in dolichol phosphate-supplemented culturesQ44145125
The formation of lipid-linked oligosaccharides in Madin-Darby canine kidney cells. Changes in oligosaccharide profiles induced by glucosamineQ44734419
Identification of manipulated variables for a glycosylation control strategyQ46978895
Parallel experimental design and multivariate analysis provides efficient screening of cell culture media supplements to improve biosimilar product quality.Q48236068
Tuning a MAb glycan profile in cell culture: Supplementing N-acetylglucosamine to favour G0 glycans without compromising productivity and cell growth.Q51714148
P433issue2
P304page(s)335-349
P577publication date2018-10-22
P1433published inMonoclonal AntibodiesQ6714645
P1476titleComprehensive manipulation of glycosylation profiles across development scales
P478volume11

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Q91808144Antibody Structure and Function: The Basis for Engineering Therapeuticscites workP2860

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