| P50 | author | Armin Kraus | Q91749833 |
| P2093 | author name string | Manfred Infanger | |
| | Alexander Romswinkel | |
| | Carlo Dietz | |
| | Florian Strube | |
| P2860 | cites work | Key Proteins Involved in Spheroid Formation and Angiogenesis in Endothelial Cells After Long-Term Exposure to Simulated Microgravity. | Q50198272 |
| | EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma | Q21144325 |
| | Effects of simulated microgravity on expression profile of microRNA in human lymphoblastoid cells | Q24595160 |
| | Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis | Q24610450 |
| | CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis | Q24642797 |
| | Simulated microgravity: critical review on the use of random positioning machines for mammalian cell culture | Q26824020 |
| | Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy | Q26826863 |
| | The role of the cytoskeleton in sensing changes in gravity by nonspecialized cells | Q26851541 |
| | Alterations of the cytoskeleton in human cells in space proved by life-cell imaging | Q27300237 |
| | Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? | Q27860893 |
| | Recent advances in targeted therapy for Ewing sarcoma | Q28079316 |
| | The widespread regulation of microRNA biogenesis, function and decay | Q28131796 |
| | Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma | Q28239992 |
| | Tumor cell interactions with the extracellular matrix during invasion and metastasis | Q28258256 |
| | Lysyl oxidase mediates hypoxic control of metastasis | Q28271667 |
| | Posttranscriptional regulation of microRNA biogenesis in animals | Q28282519 |
| | Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathway | Q28816968 |
| | Spheroid-based drug screen: considerations and practical approach | Q30052394 |
| | Signal transduction in T lymphocytes--a comparison of the data from space, the free fall machine and the random positioning machine | Q30660120 |
| | Different responsiveness of endothelial cells to vascular endothelial growth factor and basic fibroblast growth factor added to culture media under gravity and simulated microgravity | Q33517757 |
| | Multicellular tumour spheroids in radiation biology | Q33734167 |
| | Integration analysis of microRNA and mRNA expression profiles in human peripheral blood lymphocytes cultured in modeled microgravity. | Q33876262 |
| | Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro | Q33908885 |
| | Microgravity as a novel environmental signal affecting Salmonella enterica serovar Typhimurium virulence | Q34004561 |
| | Apoptosis, cell adhesion and the extracellular matrix in the three-dimensional growth of multicellular tumor spheroids | Q34060908 |
| | Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells. | Q34119354 |
| | Cell cultivation under different gravitational loads using a novel random positioning incubator | Q34470087 |
| | Growing tissues in real and simulated microgravity: new methods for tissue engineering | Q34563701 |
| | Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space | Q35033124 |
| | Spheroid formation of human thyroid cancer cells under simulated microgravity: a possible role of CTGF and CAV1 | Q35178131 |
| | Promiscuous partnerships in Ewing's sarcoma | Q35188770 |
| | 3D tissue-engineered model of Ewing's sarcoma | Q35428655 |
| | Common Effects on Cancer Cells Exerted by a Random Positioning Machine and a 2D Clinostat. | Q35746005 |
| | Identification and Validation of Housekeeping Genes for Gene Expression Analysis of Cancer Stem Cells | Q35928531 |
| | Flow perfusion effects on three-dimensional culture and drug sensitivity of Ewing sarcoma | Q35989688 |
| | Distinct effects of two CD44 isoforms on tumor growth in vivo | Q36230431 |
| | CD44 enhances tumor aggressiveness by promoting tumor cell plasticity | Q36260608 |
| | CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment | Q36306137 |
| | Microgravity elicits reproducible alterations in cytoskeletal and metabolic gene and protein expression in space-flown Caenorhabditis elegans. | Q50881043 |
| | Three-dimensional culture of melanoma cells profoundly affects gene expression profile: a high density oligonucleotide array study. | Q51593652 |
| | Simulated microgravity inhibits cell focal adhesions leading to reduced melanoma cell proliferation and metastasis via FAK/RhoA-regulated mTORC1 and AMPK pathways. | Q52680695 |
| | Plerixafor Improves Primary Tumor Response and Reduces Metastases in Cervical Cancer Treated with Radio-Chemotherapy. | Q52845899 |
| | Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity. | Q52920382 |
| | Abrogation of taxol-induced G2-M arrest and apoptosis in human ovarian cancer cells grown as multicellular tumor spheroids. | Q54335698 |
| | Semantic Analysis of Posttranslational Modification of Proteins Accumulated in Thyroid Cancer Cells Exposed to Simulated Microgravity | Q56815367 |
| | Caveolae and caveolae constituents in mechanosensing: effect of modeled microgravity on cultured human endothelial cells | Q56998795 |
| | Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - The THYROID Project | Q57672611 |
| | NKX2.2 immunohistochemistry in the distinction of ewing sarcoma from cytomorphologic mimics: Diagnostic utility and pitfalls | Q58093691 |
| | STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets | Q60469724 |
| | Skeletal Muscle Atrophy in Simulated Microgravity Might Be Triggered by Immune-Related microRNAs | Q61449580 |
| | Matrix Metalloproteinase-9 Silencing by RNA Interference Triggers the Migratory-adhesive Switch in Ewing's Sarcoma Cells | Q63432724 |
| | c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer | Q64019053 |
| | Multimodal therapy for the management of primary, nonmetastatic Ewing's sarcoma of bone: a long-term follow-up of the First Intergroup study | Q64211472 |
| | Mozobil® (Plerixafor, AMD3100), 10 years after its approval by the US Food and Drug Administration | Q64253765 |
| | Fighting Thyroid Cancer with Microgravity Research. | Q64998127 |
| | Effect of prolonged weightlessness on protein metabolism in rat red and white skeletal muscles | Q67044851 |
| | Multicellular spheroids as an in vitro tumor model | Q77636375 |
| | Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells | Q81546174 |
| | Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission | Q87114783 |
| | The Impact of Simulated Weightlessness on Endothelium-Dependent Angiogenesis and the Role of Caveolae/Caveolin-1 | Q87193389 |
| | 2D and 3D cell cultures - a comparison of different types of cancer cell cultures | Q90013037 |
| | Apoptosis Induction and Alteration of Cell Adherence in Human Lung Cancer Cells under Simulated Microgravity | Q92150600 |
| | 3D Primary Hepatocyte Culture Systems for Analyses of Liver Diseases, Drug Metabolism, and Toxicity: Emerging Culture Paradigms and Applications | Q92922119 |
| | Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction. | Q39084479 |
| | CXC chemokine receptor 4 is essential for maintenance of renal cell carcinoma-initiating cells and predicts metastasis. | Q39158412 |
| | DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma | Q39233911 |
| | Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces | Q39329602 |
| | IGF-1R/MDM2 relationship confers enhanced sensitivity to RITA in Ewing sarcoma cells | Q39371970 |
| | Upregulation of CXCR4 is functionally crucial for maintenance of stemness in drug-resistant non-small cell lung cancer cells | Q39389192 |
| | Actin-Based Adhesion Modules Mediate Cell Interactions with the Extracellular Matrix and Neighboring Cells | Q39416065 |
| | A proteomic approach to analysing spheroid formation of two human thyroid cell lines cultured on a random positioning machine | Q39552690 |
| | Effects of simulated microgravity on proliferation and chemosensitivity in malignant glioma cells | Q39821636 |
| | Caveolin-1 (CAV1) is a target of EWS/FLI-1 and a key determinant of the oncogenic phenotype and tumorigenicity of Ewing's sarcoma cells. | Q40219007 |
| | Simulated weightlessness changes the cytoskeleton and extracellular matrix proteins in papillary thyroid carcinoma cells | Q40325885 |
| | Clinorotation prevents differentiation of rat myoblastic L6 cells in association with reduced NF-kappa B signaling. | Q40445203 |
| | Changed adhesion molecule profile of Ewing tumor cell lines and xenografts under the influence of ionizing radiation. | Q40531609 |
| | Metastatic Ewing's Sarcoma: Revisiting the "Evidence on the Fence". | Q41601821 |
| | Distributions of oxygen, nutrient, and metabolic waste concentrations in multicellular spheroids and their dependence on spheroid parameters | Q41861981 |
| | Simulated microgravity triggers epithelial mesenchymal transition in human keratinocytes | Q41971417 |
| | The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma | Q42530521 |
| | Air-liquid interface cultures enhance the oxygen supply and trigger the structural and functional differentiation of intestinal porcine epithelial cells (IPEC). | Q42791361 |
| | Space shuttle flight (STS-90) enhances degradation of rat myosin heavy chain in association with activation of ubiquitin-proteasome pathway | Q43601750 |
| | Anchorage-independent multi-cellular spheroids as an in vitro model of growth signaling in Ewing tumors | Q43861826 |
| | Optimization of flexor tendon tissue engineering with a cyclic strain bioreactor | Q47289930 |
| | Protein phosphatase 1 regulatory subunit 1A in ewing sarcoma tumorigenesis and metastasis | Q47616563 |
| | Effects of simulated microgravity on DU 145 human prostate carcinoma cells | Q47863593 |
| | Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - The SPHEROIDS project | Q47971542 |
| | Modeled gravitational unloading induced downregulation of endothelin-1 in human endothelial cells. | Q48252178 |
| | Spheroid formation and modulation of tenocyte-specific gene expression under simulated microgravity | Q49529295 |
| | MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells | Q36348395 |
| | Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development. | Q36363467 |
| | Proliferation, migration and invasion of human glioma cells exposed to paclitaxel (Taxol) in vitro | Q36421995 |
| | The role of FLI-1-EWS, a fusion gene reciprocal to EWS-FLI-1, in Ewing sarcoma | Q36430114 |
| | The CXCR4-CXCL12 axis in Ewing sarcoma: promotion of tumor growth rather than metastatic disease | Q36547737 |
| | Analysis of prognostic factors in ewing sarcoma family of tumors: review of St. Jude Children's Research Hospital studies | Q36849432 |
| | Caveolin-1 modulates the ability of Ewing's sarcoma to metastasize. | Q36921347 |
| | Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine | Q36941381 |
| | ERBB4 confers metastatic capacity in Ewing sarcoma | Q37040838 |
| | The cell-cell adhesion molecule E-cadherin. | Q37251750 |
| | Microgravity induces proteomics changes involved in endoplasmic reticulum stress and mitochondrial protection | Q37285566 |
| | ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma | Q37424383 |
| | E-cadherin cell-cell adhesion in ewing tumor cells mediates suppression of anoikis through activation of the ErbB4 tyrosine kinase | Q37531718 |
| | Role and regulation of sigma S in general resistance conferred by low-shear simulated microgravity in Escherichia coli. | Q37663291 |
| | Proteome Analysis of Human Follicular Thyroid Cancer Cells Exposed to the Random Positioning Machine | Q37729123 |
| | microRNAs, RNA binding proteins and cancer | Q37757045 |
| | Using space-based investigations to inform cancer research on Earth | Q38098865 |
| | The role of the CXCL12-CXCR4/CXCR7 axis in the progression and metastasis of bone sarcomas (Review). | Q38152720 |
| | Blood pressure regulation IV: adaptive responses to weightlessness | Q38175879 |
| | Fifty years of human space travel: implications for bone and calcium research. | Q38226332 |
| | Three-dimensional models of cancer for pharmacology and cancer cell biology: capturing tumor complexity in vitro/ex vivo | Q38244951 |
| | Spaceflight-related suboptimal conditions can accentuate the altered gravity response of Drosophila transcriptome. | Q38505206 |
| | Molecular Pathways: Targeting the CXCR4-CXCL12 Axis--Untapped Potential in the Tumor Microenvironment | Q38551844 |
| | Ewing Sarcoma: Current Management and Future Approaches Through Collaboration | Q38573422 |
| | BAG3 promotes stem cell-like phenotype in breast cancer by upregulation of CXCR4 via interaction with its transcript | Q38681173 |
| | Ewing sarcoma: The clinical relevance of the insulin-like growth factor 1 and the poly-ADP-ribose-polymerase pathway. | Q38696267 |
| | Three-dimensional culture systems in cancer research: Focus on tumor spheroid model | Q38803945 |
| | CXCL14, CXCR7 expression and CXCR4 splice variant ratio associate with survival and metastases in Ewing sarcoma patients. | Q38830920 |
| | Cell spheroids: the new frontiers in in vitro models for cancer drug validation. | Q38883927 |
| | Comparison of 2D- and 3D-culture models as drug-testing platforms in breast cancer | Q38915097 |
| | Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma | Q39013447 |
| | Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers. | Q39016518 |
| | Proteomic differences between microvascular endothelial cells and the EA.hy926 cell line forming three-dimensional structures. | Q39038602 |
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 23 | |
| P921 | main subject | microgravity | Q48655 |
| P577 | publication date | 2019-12-02 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | The Role of C-X-C Chemokine Receptor Type 4 (CXCR4) in Cell Adherence and Spheroid Formation of Human Ewing's Sarcoma Cells under Simulated Microgravity | |
| P478 | volume | 20 | |