Thyroid Eye Disease: How A Novel Therapy May Change The Treatment Paradigm

scientific article published on 11 November 2019

Thyroid Eye Disease: How A Novel Therapy May Change The Treatment Paradigm is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.2147/TCRM.S193018
P932PMC publication ID6858302
P698PubMed publication ID31814726

P50authorAmy PatelQ91789194
P2093author name stringYao Wang
Raymond S Douglas
P2860cites workRelation between therapy for hyperthyroidism and the course of Graves' ophthalmopathyQ74010201
Thyrotropin receptor expression in Graves' orbital adipose/connective tissues: potential autoantigen in Graves' ophthalmopathyQ74324679
A prospective, randomized, double-blind, placebo-controlled study of orbital radiotherapy for Graves' ophthalmopathyQ74459180
Slow-release lanreotide in Graves' ophthalmopathy: A double-blind randomized, placebo-controlled clinical trialQ79775301
Full-thickeness anterior blepharotomy and transpalpebral fat decompression in Graves' orbitopathyQ81282886
Development and course of exophthalmos and ophthalmoplegia in Graves' disease with special reference to the effect of thyroidectomyQ82104621
Thyroid eye diseaseQ83446693
CD8+CD28-lymphocytes in peripheral blood and serum concentrations of soluble interleukin 6 receptor are increased in patients with Graves' orbitopathy and correlate with disease activityQ83847859
Eyebrow tissue expansion: an underappreciated entity in thyroid-associated orbitopathyQ85643449
Smoking induces overexpression of immediate early genes in active Graves' ophthalmopathyQ87611745
Teprotumumab, an insulin-like growth factor-1 receptor antagonist antibody, in the treatment of active thyroid eye disease: a focus on proptosisQ90695307
Efficacy of Tocilizumab in Patients With Moderate-to-Severe Corticosteroid-Resistant Graves Orbitopathy: A Randomized Clinical TrialQ90775985
Current and Emerging Treatment Strategies for Graves' OrbitopathyQ91118565
Tocilizumab for thyroid eye diseaseQ93333216
Rituximab for thyroid-associated ophthalmopathyQ24202845
Graves' Ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and ManagementQ26782424
Acute thyroid eye disease (TED): principles of medical and surgical managementQ26827429
Selenium and the course of mild Graves' orbitopathyQ28238021
Clinical features of Graves' ophthalmopathy in an incidence cohortQ28275743
Graves' Disease.Q30243909
Prospective, systematically recorded mycophenolate safety data in Graves' orbitopathyQ31047067
Clinical characteristics of moderate-to-severe thyroid associated ophthalmopathy in 354 Chinese casesQ33637524
Management of Graves' ophthalmopathy: reality and perspectivesQ33899550
Thyroid-associated orbitopathyQ33910021
Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes.Q34130987
The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, MinnesotaQ34164149
Rundle and his curveQ34170719
Teprotumumab for Thyroid-Associated Ophthalmopathy.Q34556184
Quality of life in patients with Graves ophthalmopathy.Q34565430
Cytokines are both villains and potential therapeutic targets in thyroid-associated ophthalmopathy: From bench to bedside.Q34763844
Efficacy of B-cell targeted therapy with rituximab in patients with active moderate to severe Graves' orbitopathy: a randomized controlled study.Q35055076
Randomized controlled trial of rituximab in patients with Graves' orbitopathyQ35055124
Bidirectional TSH and IGF-1 receptor cross talk mediates stimulation of hyaluronan secretion by Graves' disease immunoglobinsQ35096870
Impact of smoking on the response to treatment of thyroid associated ophthalmopathyQ35591093
Assessing quality of life in Australian patients with Graves' ophthalmopathyQ35591594
Treatment of thyroid associated ophthalmopathy with periocular injections of triamcinoloneQ35592595
Late reactivation of thyroid orbitopathyQ35640355
Risk factors for development or deterioration of Graves' ophthalmopathyQ35975724
Clinical features of dysthyroid optic neuropathy: a European Group on Graves' Orbitopathy (EUGOGO) surveyQ36014781
The pathophysiology of thyroid eye disease: implications for immunotherapy.Q36439938
Prominent premalar and cheek swelling: a sign of thyroid-associated orbitopathyQ36658850
The 2016 European Thyroid Association/European Group on Graves' Orbitopathy Guidelines for the Management of Graves' OrbitopathyQ36811289
B cells from patients with Graves' disease aberrantly express the IGF-1 receptor: implications for disease pathogenesis.Q36924505
Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves' orbitopathy.Q37017174
Ciclosporin and prednisone v. prednisone in treatment of Graves' ophthalmopathy: a controlled, randomized and prospective studyQ70321449
Autoantibodies to IGF-1 binding sites in thyroid associated ophthalmopathyQ71632265
Randomized trial of intravenous immunoglobulins versus prednisolone in Graves' ophthalmopathyQ71778725
Randomized double-blind trial of prednisone versus radiotherapy in Graves' ophthalmopathyQ72235149
Graves' ophthalmopathy in the absence of elevated free thyroxine and triiodothyronine levels: prevalence, natural history, and thyrotropin receptor antibody levelsQ73496914
Superoxide radical production stimulates retroocular fibroblast proliferation in Graves' ophthalmopathyQ73618559
Radiotherapy for Graves' orbitopathy: randomised placebo-controlled studyQ73761107
Visual field defects in exophthalmos associated with thyroid diseaseQ73839439
Antioxidant agents in the treatment of Graves' ophthalmopathyQ73870904
Psychosocial morbidity of Graves' orbitopathy.Q51925700
Efficacy and safety of mycophenolate mofetil in patients with active moderate-to-severe Graves' orbitopathy.Q53057871
A randomized controlled trial of orbital radiotherapy versus sham irradiation in patients with mild Graves' ophthalmopathy.Q53359335
Reactivation of Graves' orbitopathy after rehabilitative orbital decompression.Q53497830
Thyroid-associated Ophthalmopathy.Q53743982
New advances in understanding thyroid-associated ophthalmopathy and the potential role for insulin-like growth factor-I receptor.Q55024151
Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial.Q55049410
Efficacy and Safety of Three Different Cumulative Doses of Intravenous Methylprednisolone for Moderate to Severe and Active Graves' OrbitopathyQ58109526
Serial TSH-receptor antibody levels to guide the management of thyroid eye disease: the impact of smoking, immunosuppression, radio-iodine, and thyroidectomyQ58606862
Infliximab: A Novel Treatment for Sight-Threatening Thyroid Associated OphthalmopathyQ60207430
Severe unilateral orbitopathy in a patient with Hashimoto's thyroiditis - a case reportQ60915679
Orbital Radiotherapy Plus Concomitant Steroids in Moderate-to-Severe Graves' Ophthalmopathy: Good Results After Long-Term Follow-UpQ64248548
Dysthyroid optic neuropathy. Clinical profile and rationale for managementQ67350313
Orbital radiotherapy combined with high dose systemic glucocorticoids for Graves' ophthalmopathy is more effective than radiotherapy alone: results of a prospective randomized studyQ67876001
Dysthyroid optic neuropathy. The crowded orbital apex syndromeQ68005382
Treatment of dysthyroid lower lid retraction with autogenous tarsus transplantsQ68083517
Ciamexone in endocrine orbitopathy. A randomized double-blind, placebo-controlled studyQ68713051
Azathioprine in the treatment of thyroid-associated ophthalmopathyQ68713064
Prednisone and cyclosporine in the treatment of severe Graves' ophthalmopathyQ69288448
Orbital Cobalt Irradiation Combined with Systemic Corticosteroids for Graves' Ophthalmopathy: Comparison with Systemic Corticosteroids Alone*Q70251349
The surgical management of thyroid-related upper eyelid retractionQ70318726
Orbital radiation for graves ophthalmopathy: a report by the American Academy of OphthalmologyQ37033302
Treatment of lower eyelid retraction by retractor release and posterior lamellar grafting: an analysis of 659 eyelids in 400 patientsQ37180701
Update on thyroid eye disease and management.Q37406589
Evidence for an association between thyroid-stimulating hormone and insulin-like growth factor 1 receptors: a tale of two antigens implicated in Graves' disease.Q37417167
Building the Case for Insulin-Like Growth Factor Receptor-I Involvement in Thyroid-Associated Ophthalmopathy.Q37550127
Orbital decompression in thyroid eye diseaseQ37556318
Clinical review: Intravenous glucocorticoids for Graves' orbitopathy: efficacy and morbidityQ37829150
Thyroid eye disease: towards an evidence base for treatment in the 21st centuryQ37987063
Efficacy and safety of orbital radiotherapy for graves' orbitopathyQ38042043
Nonsurgical management of diplopia after orbital decompression surgeryQ38045887
Recurrent Thyroid Eye DiseaseQ38332625
Thyroid Eye Disease: Optic Neuropathy and Orbital DecompressionQ38655641
Graves' orbitopathy as a rare disease in Europe: a European Group on Graves' Orbitopathy (EUGOGO) position statement.Q38692635
Graves Lower Eyelid RetractionQ38702615
Smoking and Eye Pathologies. A Systemic Review. Part II. Retina Diseases, Uveitis, Optic Neuropathies, Thyroid-Associated OrbitopathyQ39082068
TSHR as a therapeutic target in Graves' diseaseQ39106190
Adalimumab as steroid-sparing treatment of inflammatory-stage thyroid eye diseaseQ39167512
Postoperative Changes in Strabismus, Ductions, Exophthalmometry, and Eyelid Retraction After Orbital Decompression for Thyroid OrbitopathyQ39528775
Immunosuppressant therapy of thyroid eye diseaseQ39568202
PREGO (presentation of Graves' orbitopathy) study: changes in referral patterns to European Group On Graves' Orbitopathy (EUGOGO) centres over the period from 2000 to 2012.Q40962257
Comparison of the effectiveness and tolerability of intravenous or oral glucocorticoids associated with orbital radiotherapy in the management of severe Graves' ophthalmopathy: results of a prospective, single-blind, randomized studyQ43705603
Lid retraction and levator aponeurosis defects in Graves' eye disease.Q43754016
Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblastsQ43845891
Aberrant expression of the insulin-like growth factor-1 receptor by T cells from patients with Graves' disease may carry functional consequences for disease pathogenesis.Q44256446
High-dose intravenous immunoglobulin treatment in Graves' ophthalmopathyQ44504847
Immunoglobulins from patients with Graves' disease induce hyaluronan synthesis in their orbital fibroblasts through the self-antigen, insulin-like growth factor-I receptor.Q45096631
Octreotide (long-acting release formulation) treatment in patients with graves' orbitopathy: clinical results of a four-month, randomized, placebo-controlled, double-blind studyQ45161391
Double-blind, placebo-controlled trial of octreotide long-acting repeatable (LAR) in thyroid-associated ophthalmopathy.Q45173583
Reactivation of thyroid-associated orbitopathy after cataract surgery.Q46069886
Combined orbital irradiation and systemic steroids compared with systemic steroids alone in the management of moderate-to-severe Graves' ophthalmopathy: a preliminary study.Q46748284
Methylprednisolone pulse therapy for patients with moderately severe Graves' orbitopathy: a prospective, randomized, placebo-controlled studyQ46784134
Tocilizumab as a steroid sparing agent for the treatment of Graves' orbitopathyQ47160950
IGF-I receptor and thyroid-associated ophthalmopathyQ47259453
Mycophenolate plus methylprednisolone versus methylprednisolone alone in active, moderate-to-severe Graves' orbitopathy (MINGO): a randomised, observer-masked, multicentre trial.Q49360067
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P921main subjecteye diseaseQ3041498
P304page(s)1305-1318
P577publication date2019-11-11
P1433published inTherapeutics and Clinical Risk ManagementQ15766913
P1476titleThyroid Eye Disease: How A Novel Therapy May Change The Treatment Paradigm
P478volume15

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