Engineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid

scientific article published on 10 July 2019

Engineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMBEN.2019.07.003
P698PubMed publication ID31301358

P50authorGregory StephanopoulosQ88097878
P2093author name stringHuimin Yu
Fangyu Cheng
P2860cites workOptForce: an optimization procedure for identifying all genetic manipulations leading to targeted overproductionsQ21145339
Small mobilizable multi-purpose cloning vectors derived from the Escherichia coli plasmids pK18 and pK19: selection of defined deletions in the chromosome of Corynebacterium glutamicumQ29615259
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Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthineQ39531679
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13C metabolic flux analysis for larger scale cultivation using gas chromatography-combustion-isotope ratio mass spectrometryQ43164957
Hyaluronic acid production is enhanced by the additional co-expression of UDP-glucose pyrophosphorylase in Lactococcus lactisQ43253707
clpC and clpP1P2 gene expression in Corynebacterium glutamicum is controlled by a regulatory network involving the transcriptional regulators ClgR and HspR as well as the ECF sigma factor sigmaH.Q44818476
A recombinant E. coli bioprocess for hyaluronan synthesisQ46077820
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Improved Yield of High Molecular Weight Hyaluronic Acid Production in a Stable Strain of Streptococcus zooepidemicus via the Elimination of the Hyaluronidase-Encoding GeneQ47213728
Key Role of the Carboxyl Terminus of Hyaluronan Synthase in Processive Synthesis and Size Control of Hyaluronic Acid Polymers.Q47235774
Chromosomal integration of hyaluronic acid synthesis (has) genes enhances the molecular weight of hyaluronan produced in Lactococcus lactis.Q47447871
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Enhanced Biosynthesis of Hyaluronic Acid Using Engineered Corynebacterium glutamicum Via Metabolic Pathway RegulationQ47720306
Reprogramming One-Carbon Metabolic Pathways To Decouple l-Serine Catabolism from Cell Growth in Corynebacterium glutamicum.Q48278045
Hyaluronan production and molecular weight is enhanced in pathway-engineered strains of lactate dehydrogenase-deficient Lactococcus lactisQ50290234
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Regulating malonyl-CoA metabolism via synthetic antisense RNAs for enhanced biosynthesis of natural products.Q50990467
Metabolic engineering of Corynebacterium glutamicum for the production of 3-hydroxypropionic acid from glucose and xylose.Q51087740
Genetic and biochemical characterization of genes involved in hyaluronic acid synthesis in Streptococcus zooepidemicus.Q51565221
High-titer biosynthesis of hyaluronic acid by recombinant Corynebacterium glutamicum.Q51588796
Metabolic engineering of Bacillus subtilis for the efficient biosynthesis of uniform hyaluronic acid with controlled molecular weights.Q51829347
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Evaluation of magnetic nanoparticles influence on hyaluronic acid production from Streptococcus equi.Q52565737
Metabolic engineering to guide evolution - Creating a novel mode for L-valine production with Corynebacterium glutamicum.Q52664242
Hyaluronic acid production by recombinant Streptococcus thermophilus.Q54367027
The impact of PHB accumulation on L-glutamate production by recombinant Corynebacterium glutamicum.Q54440086
Synthetic redesign of central carbon and redox metabolism for high yield production of N-acetylglucosamine in Bacillus subtilisQ57812719
Hyaluronic acid production enhancement via genetically modification and culture medium optimization in Lactobacillus acidophilusQ57813478
From zero to hero—Design-based systems metabolic engineering of Corynebacterium glutamicum for l-lysine productionQ57988563
Systems level engineering of Corynebacterium glutamicum - Reprogramming translational efficiency for superior productionQ57988688
Core element characterization of Rhodococcus promoters and development of a promoter-RBS mini-pool with different activity levels for efficient gene expressionQ88456926
Metabolically engineered Corynebacterium glutamicum for bio-based production of chemicals, fuels, materials, and healthcare productsQ90385075
Reconstruction of tricarboxylic acid cycle in Corynebacterium glutamicum with a genome-scale metabolic network model for trans-4-hydroxyproline productionQ90917535
Biosynthesis of Chondroitin in Engineered Corynebacterium glutamicumQ91255112
Antisense RNA-Based Strategy for Enhancing Surfactin Production in Bacillus subtilis TS1726 via Overexpression of the Unconventional Biotin Carboxylase II To Enhance ACCase ActivityQ91288213
P921main subjectCorynebacterium glutamicumQ292314
P304page(s)276-289
P577publication date2019-07-10
P1433published inMetabolic EngineeringQ6822334
P1476titleEngineering Corynebacterium glutamicum for high-titer biosynthesis of hyaluronic acid
P478volume55

Reverse relations

Q96609336Eliminating the capsule-like layer to promote glucose uptake for hyaluronan production by engineered Corynebacterium glutamicumcites workP2860

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