Chimeric Capsid Proteins Impact Transduction Efficiency of Haploid Adeno-Associated Virus Vectors

scientific article published on 09 December 2019

Chimeric Capsid Proteins Impact Transduction Efficiency of Haploid Adeno-Associated Virus Vectors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/V11121138
P932PMC publication ID6950324
P698PubMed publication ID31835440

P50authorEllie Azure FrostQ91963188
P2093author name stringChengwen Li
R Jude Samulski
Zheng Chai
Xintao Zhang
Amanda Lee Dobbins
P2860cites workThe atomic structure of adeno-associated virus (AAV-2), a vector for human gene therapy.Q24533492
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Adeno-associated virus type 2 VP2 capsid protein is nonessential and can tolerate large peptide insertions at its N terminusQ24563214
Cross-dressing the virion: the transcapsidation of adeno-associated virus serotypes functionally defines subgroupsQ24623923
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A comprehensive review of retinal gene therapyQ27023914
Creation of a mouse expressing defective human factor IXQ28585072
Comparative analysis of adeno-associated virus capsid stability and dynamicsQ30557598
The VP1 capsid protein of adeno-associated virus type 2 is carrying a phospholipase A2 domain required for virus infectivityQ34124491
AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.Q34168942
Selective in vivo targeting of human liver tumors by optimized AAV3 vectors in a murine xenograft modelQ34729878
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Long-term safety and efficacy of factor IX gene therapy in hemophilia B.Q34783922
Terminal N-linked galactose is the primary receptor for adeno-associated virus 9.Q34787342
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Engraftment of a galactose receptor footprint onto adeno-associated viral capsids improves transduction efficiencyQ37213826
Adeno-associated virus serotypes for gene therapeutics.Q38570101
Application of polyploid adeno-associated virus vectors for transduction enhancement and neutralizing antibody evasionQ38645275
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Gene therapy for the CNS using AAVs: The impact of systemic delivery by AAV9.Q38956595
Stability and compatibility of recombinant adeno-associated virus under conditions commonly encountered in human gene therapy trialsQ39024016
Unique characteristics of AAV1, 2, and 5 viral entry, intracellular trafficking, and nuclear import define transduction efficiency in HeLa cells.Q39406314
Structure and dynamics of adeno-associated virus serotype 1 VP1-unique N-terminal domain and its role in capsid traffickingQ39792135
Assembly of viruslike particles by recombinant structural proteins of adeno-associated virus type 2 in insect cellsQ40061611
Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virionsQ40132033
Nucleotide sequence and organization of the adeno-associated virus 2 genomeQ40143539
Comparison of the ability of adeno-associated viral vectors pseudotyped with serotype 2, 5, and 8 capsid proteins to mediate efficient transduction of the liver in murine and nonhuman primate modelsQ40418515
Electron cryo-microscopy and image reconstruction of adeno-associated virus type 2 empty capsidsQ41630679
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytesQ42739394
Endocytic processing of adeno-associated virus type 8 vectors for transduction of target cellsQ45357434
First AAV gene therapy poised for landmark approvalQ45874199
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P577publication date2019-12-09
P1433published inVirusesQ7935305
P1476titleChimeric Capsid Proteins Impact Transduction Efficiency of Haploid Adeno-Associated Virus Vectors
P478volume11

Reverse relations

Q99559716Bound Protein and Peptide-Based Strategies for Adeno-associated Virus Vector-Mediated Gene Therapy: Where do We Stand Now?cites workP2860

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