Clinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: a randomized controlled trial

scientific article published on 15 April 2020

Clinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: a randomized controlled trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S40560-020-00442-7
P932PMC publication ID7158081
P698PubMed publication ID32318268

P2093author name stringPitsucha Sanguanwit
Preecha Montakantikul
Jetjamnong Sueajai
Pitchaya Dilokpattanamongkol
Saranya Auparakkitanon
Tospon Lertwattanachai
Viratch Tangsujaritvijit
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Unrevealing culture-negative severe sepsisQ26830520
Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patientsQ33552161
Beta-lactam dosing in critically ill patients with septic shock and continuous renal replacement therapyQ33821554
Population pharmacokinetics and Monte Carlo dosing simulations of meropenem during the early phase of severe sepsis and septic shock in critically ill patients in intensive care unitsQ35607715
Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactamsQ35908084
Empiric antimicrobial therapy in severe sepsis and septic shock: optimizing pathogen clearanceQ36089167
Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast AsiaQ36866920
An alternate pathophysiologic paradigm of sepsis and septic shock: implications for optimizing antimicrobial therapyQ37563029
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The immune system's role in sepsis progression, resolution, and long-term outcomeQ38991057
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Optimizing β-lactams treatment in critically-ill patients using pharmacokinetics/pharmacodynamics targets: are first conventional doses effective?Q39344408
Modelled target attainment after meropenem infusion in patients with severe nosocomial pneumonia: the PROMESSE studyQ41741255
Role of renal function in risk assessment of target non-attainment after standard dosing of meropenem in critically ill patients: a prospective observational study.Q42654588
Maximally effective dosing regimens of meropenem in patients with septic shock.Q47624900
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DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?Q57237700
Effect of renal clearance and continuous renal replacement therapy on appropriateness of recommended meropenem dosing regimens in critically ill patients with susceptible life-threatening infectionsQ57289588
Pharmacokinetic/Pharmacodynamic Considerations of Beta-Lactam Antibiotics in Adult Critically Ill PatientsQ88271342
Sepsis and septic shockQ89222248
Clinical outcomes of prolonged infusion (extended infusion or continuous infusion) versus intermittent bolus of meropenem in severe infection: A meta-analysisQ90612119
Post-sepsis syndrome - an evolving entity that afflicts survivors of sepsisQ92354721
Augmented renal clearance is associated with inadequate antibiotic pharmacokinetic/pharmacodynamic target in Asian ICU population: a prospective observational studyQ93185288
P921main subjectsepsisQ183134
meropenemQ421670
septic shockQ1765564
P304page(s)26
P577publication date2020-04-15
P1433published inJournal of intensive careQ27725973
P1476titleClinical outcomes of empirical high-dose meropenem in critically ill patients with sepsis and septic shock: a randomized controlled trial
P478volume8

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