PF-06439535 (a Bevacizumab Biosimilar) Compared with Reference Bevacizumab (Avastin®), Both Plus Paclitaxel and Carboplatin, as First-Line Treatment for Advanced Non-Squamous Non-Small-Cell Lung Cancer: A Randomized, Double-Blind Study

scientific article published on 01 October 2019

PF-06439535 (a Bevacizumab Biosimilar) Compared with Reference Bevacizumab (Avastin®), Both Plus Paclitaxel and Carboplatin, as First-Line Treatment for Advanced Non-Squamous Non-Small-Cell Lung Cancer: A Randomized, Double-Blind Study is …
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scholarly articleQ13442814

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P356DOI10.1007/S40259-019-00363-4
P932PMC publication ID6790355
P698PubMed publication ID31338773

P50authorNiels ReinmuthQ92140332
Maciej BrylQ92805623
P2093author name stringIgor Bondarenko
Vladimir Vladimirov
Kostas Syrigos
Kazuo Kasahara
Katherine Liau
Fiona Hilton
Angel H Bair
Manuela Zereu
P2860cites workNonclinical assessments of the potential biosimilar PF-06439535 and bevacizumabQ88159233
Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLCQ88973544
Efficacy and Safety of the Biosimilar ABP 215 Compared with Bevacizumab in Patients with Advanced Nonsquamous Non-small Cell Lung Cancer (MAPLE): A Randomized, Double-blind, Phase III StudyQ90928646
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
The biology of VEGF and its receptorsQ27860704
New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1)Q28131668
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancerQ28278736
Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung CancerQ29620913
Improved survival with bevacizumab in advanced cervical cancerQ33566222
Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapyQ34157098
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancerQ34323659
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapyQ34547495
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A phase I pharmacokinetics study comparing PF-06439535 (a potential biosimilar) with bevacizumab in healthy male volunteersQ36762864
Barriers to the Access of Bevacizumab in Patients with Solid Tumors and the Potential Impact of Biosimilars: A Physician SurveyQ37731321
Effect of a Proposed Trastuzumab Biosimilar Compared With Trastuzumab on Overall Response Rate in Patients With ERBB2 (HER2)-Positive Metastatic Breast Cancer: A Randomized Clinical Trial.Q38383854
Bevacizumab in Colorectal Cancer: Current Role in Treatment and the Potential of BiosimilarsQ38643555
CT-P6 compared with reference trastuzumab for HER2-positive breast cancer: a randomised, double-blind, active-controlled, phase 3 equivalence trialQ39358281
The IASLC Lung Cancer Staging Project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM Classification of malignant tumoursQ39512984
Comparative analysis of two ratesQ41501755
Randomized phase II study of first-line carboplatin-paclitaxel with or without bevacizumab in Japanese patients with advanced non-squamous non-small-cell lung cancerQ42632045
Rituximab biosimilar and reference rituximab in patients with previously untreated advanced follicular lymphoma (ASSIST-FL): primary results from a confirmatory phase 3, double-blind, randomised, controlled study.Q48619267
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Biosimilars: a position paper of the European Society for Medical Oncology, with particular reference to oncology prescribers.Q54135887
Metastatic non-small cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upQ57051777
Efficacy and safety of ABP 980 compared with reference trastuzumab in women with HER2-positive early breast cancer (LILAC study): a randomised, double-blind, phase 3 trialQ57110471
Efficacy, pharmacokinetics, and safety of the biosimilar CT-P10 in comparison with rituximab in patients with previously untreated low-tumour-burden follicular lymphoma: a randomised, double-blind, parallel-group, phase 3 trialQ58565563
P433issue5
P921main subjectbevacizumabQ413299
carboplatinQ415588
paclitaxelQ423762
P304page(s)555-570
P577publication date2019-10-01
P1433published inBioDrugsQ4914612
P1476titlePF-06439535 (a Bevacizumab Biosimilar) Compared with Reference Bevacizumab (Avastin®), Both Plus Paclitaxel and Carboplatin, as First-Line Treatment for Advanced Non-Squamous Non-Small-Cell Lung Cancer: A Randomized, Double-Blind Study
P478volume33

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Q92953557Inhaled chemotherapy adverse effects: mechanisms and protection methodscites workP2860

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