Ganoderma lucidum Extract Reduces the Motility of Breast Cancer Cells Mediated by the RAC⁻Lamellipodin Axis

scientific article published on 19 May 2019

Ganoderma lucidum Extract Reduces the Motility of Breast Cancer Cells Mediated by the RAC⁻Lamellipodin Axis is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/NU11051116
P932PMC publication ID6567024
P698PubMed publication ID31109134

P50authorIvette J Suarez-ArroyoQ59701209
Astrid Zayas-SantiagoQ88649878
Michelle M Martínez-MontemayorQ41168810
P2093author name stringAriana Acevedo-Díaz
Gabriela Ortiz-Soto
P2860cites workRac1 and Rac3 isoform activation is involved in the invasive and metastatic phenotype of human breast cancer cellsQ21195236
Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.Q24337515
Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and diseaseQ26853181
Tumor cell migration in complex microenvironmentsQ27027489
Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.Q27309896
Rho GTPases and the actin cytoskeletonQ27860579
Rho GTPases and actin dynamics in membrane protrusions and vesicle traffickingQ28261534
Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamicsQ28286512
Dissemination and growth of cancer cells in metastatic sitesQ29555846
A FAK-Cas-Rac-lamellipodin signaling module transduces extracellular matrix stiffness into mechanosensitive cell cycling.Q30407809
FAK phosphorylation at Tyr-925 regulates cross-talk between focal adhesion turnover and cell protrusionQ30499286
Coactivation of Rac1 and Cdc42 at lamellipodia and membrane ruffles induced by epidermal growth factor.Q30539004
Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivoQ30557898
Therapeutic sensitivity to Rac GTPase inhibition requires consequential suppression of mTORC1, AKT, and MEK signaling in breast cancerQ33591690
Anti-tumor effects of Ganoderma lucidum (reishi) in inflammatory breast cancer in in vivo and in vitro models.Q34612111
Ganoderma lucidum inhibits proliferation of human breast cancer cells by down-regulation of estrogen receptor and NF-kappaB signaling.Q53609224
B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine.Q55101954
Effects of non-steroidal anti-inflammatory drug-activated gene-1 on Ganoderma lucidum polysaccharides-induced apoptosis of human prostate cancer PC-3 cellsQ57066655
extract (GLE) impairs breast cancer stem cells by targeting the STAT3 pathwayQ59809198
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countriesQ60142201
Identification of Biologically Active Compounds and Synthesis of Improved Derivatives That Confer Anti-cancer ActivitiesQ64228655
Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cellsQ78454290
Ganoderma lucidum suppresses growth of breast cancer cells through the inhibition of Akt/NF-kappaB signalingQ80872378
Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathwayQ35034732
Ganoderma lucidum (Reishi) inhibits cancer cell growth and expression of key molecules in inflammatory breast cancerQ35448482
Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.Q35564850
Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis.Q35620884
Ganoderma lucidum (Reishi) in cancer treatmentQ35624532
Estrogen and resveratrol regulate Rac and Cdc42 signaling to the actin cytoskeleton of metastatic breast cancer cellsQ35668666
Rac signaling in breast cancer: a tale of GEFs and GAPs.Q35854151
Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasionQ36285709
The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genesQ36528110
Regulation of the actin cytoskeleton in cancer cell migration and invasionQ36574131
Ganoderma lucidum Combined with the EGFR Tyrosine Kinase Inhibitor, Erlotinib Synergize to Reduce Inflammatory Breast Cancer ProgressionQ36657315
The regulation of cell motility and chemotaxis by phospholipid signalingQ37089555
Cdc42 overexpression induces hyperbranching in the developing mammary gland by enhancing cell migration.Q37690367
Mechanisms of motility in metastasizing cellsQ37749124
Steering cell migration: lamellipodium dynamics and the regulation of directional persistenceQ38242035
Ganoderma lucidum total triterpenes induce apoptosis in MCF-7 cells and attenuate DMBA induced mammary and skin carcinomas in experimental animalsQ38724652
Expression of the WASP verprolin-homologues (WAVE members) in human breast cancerQ39977497
Ganoderma spp.: A Promising Adjuvant Treatment for Breast Cancer.Q41168695
Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy.Q42032794
Molecular aspects of tumor cell migration and invasion.Q43116270
Breast cancer statistics, 2017, racial disparity in mortality by state.Q47621558
The Rac GTPase in Cancer: From Old Concepts to New ParadigmsQ47953335
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue5
P921main subjectGanoderma lucidumQ271098
P577publication date2019-05-19
P1433published inNutrientsQ7070485
P1476titleGanoderma lucidum Extract Reduces the Motility of Breast Cancer Cells Mediated by the RAC⁻Lamellipodin Axis
P478volume11

Search more.