| scholarly article | Q13442814 |
| P50 | author | Michaël E Belloy | Q89399798 |
| P2093 | author name string | Michael D Greicius | |
| Valerio Napolioni | |||
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| Progression of regional grey matter atrophy in multiple sclerosis. | Q55362467 | ||
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| Lack of association between APOE gene polymorphisms and amyotrophic lateral sclerosis: A comprehensive meta-analysis | Q58125365 | ||
| Apolipoprotein E gene in frontotemporal dementia: an association study and meta-analysis | Q58485812 | ||
| Apolipoprotein E4 allele in a population–based study of early–onset Alzheimer's disease | Q60233030 | ||
| The baboon apolipoprotein E gene: Structure, expression, and linkage with the gene for apolipoprotein C-I | Q61450440 | ||
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| APOE ε4 increases risk for dementia in pure synucleinopathies | Q36634159 | ||
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| ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions | Q36835522 | ||
| Apolipoprotein E e4 allele frequency in patients with multiple system atrophy | Q36856567 | ||
| An antisense oligonucleotide against SOD1 delivered intrathecally for patients with SOD1 familial amyotrophic lateral sclerosis: a phase 1, randomised, first-in-man study | Q37015657 | ||
| Apolipoprotein E epsilon4 is associated with disease-specific effects on brain atrophy in Alzheimer's disease and frontotemporal dementia | Q37100964 | ||
| Common polygenic variation enhances risk prediction for Alzheimer's disease | Q37220545 | ||
| Understanding the association of apolipoprotein E4 with Alzheimer disease: clues from its structure | Q37307244 | ||
| Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease | Q37442011 | ||
| Evolution of apolipoprotein E: mouse sequence and evidence for an 11-nucleotide ancestral unit | Q37556999 | ||
| Apolipoprotein E mRNA is abundant in the brain and adrenals, as well as in the liver, and is present in other peripheral tissues of rats and marmosets | Q37672903 | ||
| CSF Apo-E levels associate with cognitive decline and MRI changes | Q37705204 | ||
| Mechanisms linking apolipoprotein E isoforms with cardiovascular and neurological diseases | Q37763476 | ||
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| ApoE genotype: from geographic distribution to function and responsiveness to dietary factors | Q38008109 | ||
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| Apolipoprotein E in Alzheimer's disease: an update | Q38211371 | ||
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| Exploring the origins of grey matter damage in multiple sclerosis. | Q38361889 | ||
| Genetics of Vascular Dementia: Systematic Review and Meta-Analysis | Q38401872 | ||
| Apolipoprotein E Genotype and Sex Risk Factors for Alzheimer Disease: A Meta-analysis | Q38605663 | ||
| The Biological Foundation of the Genetic Association of TOMM40 with Late-onset Alzheimer's disease. | Q38646489 | ||
| A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease | Q38672340 | ||
| Meta-analysis of apolipoprotein E levels in the cerebrospinal fluid of patients with Alzheimer's disease. | Q38685022 | ||
| Cognitive decline in Parkinson disease | Q38751099 | ||
| TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia. | Q38754523 | ||
| Updated meta-analysis of the role of APOE ε2/ε3/ε4 alleles in frontotemporal lobar degeneration | Q38795201 | ||
| Decoding ALS: from genes to mechanism. | Q39004348 | ||
| ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion | Q39006798 | ||
| Plasma levels of apolipoprotein E and risk of dementia in the general population | Q39084782 | ||
| Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins | Q39155261 | ||
| Plasma levels of apolipoprotein E, APOE genotype and risk of dementia and ischemic heart disease: A review | Q39199476 | ||
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| Proposed nomenclature of apoE isoproteins, apoE genotypes, and phenotypes. | Q50715903 | ||
| APOE ε4 is associated with exacerbation of cognitive decline in patients with multiple sclerosis. | Q50990813 | ||
| The effect of the APOE-epsilon4 allele and ACE-I/D polymorphism on cognition during a two-year follow-up in first-ever stroke patients. | Q51046659 | ||
| Gene-based association studies report genetic links for clinical subtypes of frontotemporal dementia. | Q51067635 | ||
| Apolipoprotein E levels and apolipoprotein E genotypes in incident cardiovascular disease risk in subjects of the Prevention of Renal and Vascular End-stage disease study. | Q51541584 | ||
| TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function. | Q51764852 | ||
| Cognitive impairment and the role of the ApoE epsilon4-allele after stroke--a 13 months follow-up study. | Q51796360 | ||
| Impact of hypertension and apolipoprotein E4 on poststroke cognition in subjects >75 years of age. | Q51927529 | ||
| APOE epsilon4 and cognitive decline in older stroke patients with early cognitive impairment. | Q51936235 | ||
| APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study. | Q51982797 | ||
| Apolipophorin II/I, apolipoprotein B, vitellogenin, and microsomal triglyceride transfer protein genes are derived from a common ancestor. | Q52570918 | ||
| Cell-specific production, secretion, and function of apolipoprotein E. | Q52667884 | ||
| Arginine residues at codons 112 and 158 in the apolipoprotein E gene correspond to the ancestral state in humans. | Q52846307 | ||
| The apolipoprotein E (APOE) gene appears functionally monomorphic in chimpanzees (Pan troglodytes) | Q28714850 | ||
| Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database | Q29417106 | ||
| Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals | Q30414047 | ||
| APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study | Q30425779 | ||
| Variants at APOE influence risk of deep and lobar intracerebral hemorrhage | Q30429407 | ||
| Phylogenetic distribution of apolipoproteins A-I and E in vertebrates as determined by Western blot analysis | Q30663881 | ||
| Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease | Q31052271 | ||
| Multiple system atrophy/progressive supranuclear palsy: alpha-Synuclein, synphilin, tau, and APOE. | Q33181542 | ||
| Effect of ApoE and tau on age of onset of progressive supranuclear palsy and multiple system atrophy | Q33182513 | ||
| APOE epsilon4 and cognitive dysfunction in multiple sclerosis: a review | Q33349070 | ||
| Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females | Q33563135 | ||
| APOE ε4 and the risk for Alzheimer disease and cognitive decline in African Americans and Yoruba | Q33575559 | ||
| APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease | Q33629402 | ||
| Clinical and pathologic presentation in Parkinson's disease by apolipoprotein e4 allele status | Q33638836 | ||
| APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging | Q33695738 | ||
| Vascular pathology in the aged human brain | Q33699436 | ||
| Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan | Q33707773 | ||
| Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. | Q33717326 | ||
| Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis | Q33777535 | ||
| Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium | Q33869820 | ||
| APOE epsilon4 and the cognitive genetics of multiple sclerosis | Q33871703 | ||
| Effect of APOE ε4 allele on survival and fertility in an adverse environment | Q33880361 | ||
| A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping or DNA sequencing. V. Analysis of case/control sampling designs: Alzheimer's disease and the apoprotein E locus | Q33965127 | ||
| Sex modifies the APOE-related risk of developing Alzheimer disease | Q33984761 | ||
| APOε4 is associated with enhanced in vivo innate immune responses in human subjects | Q34017080 | ||
| Is apolipoprotein E4 an important risk factor for vascular dementia? | Q34028845 | ||
| Cerebral amyloid angiopathy in the elderly | Q34108298 | ||
| Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism | Q34144158 | ||
| A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease | Q34159318 | ||
| Molecular signatures in post-mortem brain tissue of younger individuals at high risk for Alzheimer's disease as based on APOE genotype | Q34192190 | ||
| Cholesterol metabolism in the brain | Q34193085 | ||
| Phenotypes of apolipoprotein B and apolipoprotein E after liver transplantation | Q34225777 | ||
| Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies | Q34332809 | ||
| Interactions of pathological proteins in neurodegenerative diseases | Q39236779 | ||
| Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease | Q39257249 | ||
| Evolution of human apolipoprotein E (APOE) isoforms: Gene structure, protein function and interaction with dietary factors | Q39396530 | ||
| Untangling Genetic Risk for Alzheimer's Disease | Q39407560 | ||
| Apolipoprotein E predicts incident cardiovascular disease risk in women but not in men with concurrently high levels of high-density lipoprotein cholesterol and C-reactive protein | Q39666928 | ||
| Understanding the genetics of APOE and TOMM40 and role of mitochondrial structure and function in clinical pharmacology of Alzheimer's disease. | Q39787590 | ||
| Familial hyperlipoproteinemia type III: Deficiency of a specific apolipoprotein (APO E-III) in the very-low-density lipoproteins | Q39947676 | ||
| Association of APOE gene polymorphism with lipid profile and coronary artery disease in Afro-Caribbeans. | Q40114877 | ||
| Multisystem Lewy body disease and the other parkinsonian disorders | Q40260539 | ||
| Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis | Q40374258 | ||
| Apolipoprotein E alleles as risk factors in Alzheimer's disease | Q41036434 | ||
| Association between polymorphisms in the promoter region of the apolipoprotein E (APOE) gene and Alzheimer's disease: A meta-analysis | Q41582440 | ||
| Evidence for an interaction between apolipoprotein E genotype, gender, and Alzheimer disease. | Q41710472 | ||
| FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga | Q42214158 | ||
| APOE and other loci affect age-at-onset in Alzheimer's disease families with PS2 mutation | Q42636749 | ||
| Effects of the absence of apolipoprotein e on lipoproteins, neurocognitive function, and retinal function | Q43085965 | ||
| Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups: The INTERHEART Genetics Study | Q43209474 | ||
| APOE genotype, lipids, and coronary heart disease risk: a prospective population study | Q43295111 | ||
| Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments | Q43809094 | ||
| Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for apolipoprotein e isoforms | Q43971666 | ||
| APOE genotype, ethnicity, and the risk of cerebral hemorrhage | Q44148095 | ||
| Regionally specific modulation of brain apolipoprotein E in the mouse during the estrous cycle and by exogenous 17β estradiol | Q44614356 | ||
| Apolipoprotein E (APOE) allele distribution in the world. Is APOE*4 a 'thrifty' allele? | Q44620202 | ||
| ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE. | Q44989710 | ||
| African-American TOMM40'523-APOE haplotypes are admixture of West African and Caucasian alleles. | Q45063849 | ||
| Therapies targeting DNA and RNA in Huntington's disease | Q45304275 | ||
| Clinicopathological correlations in behavioural variant frontotemporal dementia. | Q45952280 | ||
| Dietary cholesterol and estrogen administration elevate brain apolipoprotein E in mice by different mechanisms. | Q46111259 | ||
| ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy | Q46160288 | ||
| Astrocytes and microglia respond to estrogen with increased apoE mRNA in vivo and in vitro | Q46296108 | ||
| Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus. | Q46529938 | ||
| Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice | Q46738149 | ||
| Apolipoprotein E and neurocognitive function--in reply | Q46823650 | ||
| Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity | Q47146693 | ||
| Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis. | Q47319247 | ||
| Antisense oligonucleotides: the next frontier for treatment of neurological disorders | Q47344432 | ||
| The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases | Q47568641 | ||
| Human Central Nervous System (CNS) ApoE Isoforms Are Increased by Age, Differentially Altered by Amyloidosis, and Relative Amounts Reversed in the CNS Compared with Plasma | Q47599699 | ||
| Prevalence and Natural History of Superficial Siderosis: A Population-Based Study | Q47602999 | ||
| Cognition in multiple sclerosis: State of the field and priorities for the future. | Q47726760 | ||
| Polymorphisms of MTHFR, eNOS, ACE, AGT, ApoE, PON1, PDE4D, and Ischemic Stroke: Meta-Analysis | Q47861569 | ||
| The missing ApoE allele | Q48082099 | ||
| Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent | Q48087117 | ||
| Genotype-related differences of hippocampal apolipoprotein E levels only in early stages of neuropathological changes in Alzheimer's disease | Q48468827 | ||
| The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase | Q48473978 | ||
| Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease | Q48493687 | ||
| Relationship between apolipoprotein E and the amyloid deposits and dystrophic neurites of Alzheimer's disease | Q48538358 | ||
| Association between ApoE epsilon4 and cognitive impairment after stroke | Q48587364 | ||
| Apolipoprotein E genotype as a risk factor for susceptibility to and dementia in Parkinson's disease | Q48692087 | ||
| Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease | Q48795523 | ||
| The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900. | Q34395093 | ||
| The overlap between vascular disease and Alzheimer's disease--lessons from pathology | Q34484708 | ||
| More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration | Q34557404 | ||
| The role of apolipoprotein E in Alzheimer's disease | Q34603092 | ||
| Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases | Q34621541 | ||
| Lipoprotein receptors in the nervous system | Q34667437 | ||
| Apolipoproteins and aging: emerging mechanisms | Q34688023 | ||
| Declining brain activity in cognitively normal apolipoprotein E epsilon 4 heterozygotes: A foundation for using positron emission tomography to efficiently test treatments to prevent Alzheimer's disease. | Q34727992 | ||
| Apolipoprotein E, gender, and Alzheimer's disease: an overlooked, but potent and promising interaction | Q34808510 | ||
| GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy | Q34974751 | ||
| Role of cholesterol in synapse formation and function | Q35089443 | ||
| Primary dysbetalipoproteinemia: predominance of a specific apoprotein species in triglyceride-rich lipoproteins | Q35107934 | ||
| Cerebral amyloid angiopathy with and without hemorrhage: evidence for different disease phenotypes | Q35195646 | ||
| Human apoE isoforms differentially regulate brain amyloid-β peptide clearance | Q35334161 | ||
| Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels. | Q35337926 | ||
| A genome-wide association study of aging | Q35343147 | ||
| Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited | Q35347421 | ||
| The allelic modulation of apolipoprotein E expression by oestrogen: potential relevance for Alzheimer's disease | Q35444823 | ||
| Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease | Q35484526 | ||
| Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease? | Q35488917 | ||
| Clinical Features of Alzheimer Disease With and Without Lewy Bodies | Q35850390 | ||
| Gender difference in apolipoprotein E-associated risk for familial Alzheimer disease: a possible clue to the higher incidence of Alzheimer disease in women. | Q35881785 | ||
| The fourth apolipoprotein E haplotype found in the Yoruba of Ibadan | Q35998163 | ||
| APOE and cerebral amyloid angiopathy in community-dwelling older persons | Q36173680 | ||
| Reducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice | Q36206696 | ||
| Association between Apolipoprotein E polymorphism and myocardial infarction risk: A systematic review and meta-analysis | Q36260764 | ||
| Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease | Q36283394 | ||
| Apolipoprotein E does not cross the blood-cerebrospinal fluid barrier, as revealed by an improved technique for sampling CSF from mice | Q36454486 | ||
| APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers | Q36472177 | ||
| The quest for genetic determinants of human longevity: challenges and insights | Q36481541 | ||
| The association between apolipoprotein E and multiple sclerosis | Q36516912 | ||
| Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo | Q36539906 | ||
| Accelerated pericyte degeneration and blood-brain barrier breakdown in apolipoprotein E4 carriers with Alzheimer's disease. | Q36593210 | ||
| Comprehensive search for Alzheimer disease susceptibility loci in the APOE region | Q36630671 | ||
| P433 | issue | 5 | |
| P921 | main subject | Alzheimer's disease | Q11081 |
| P304 | page(s) | 820-838 | |
| P577 | publication date | 2019-03-01 | |
| P1433 | published in | Neuron | Q3338676 |
| P1476 | title | A Quarter Century of APOE and Alzheimer's Disease: Progress to Date and the Path Forward | |
| P478 | volume | 101 |
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