Simultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats

scientific article published on 01 July 2019

Simultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats is …
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scholarly articleQ13442814

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P356DOI10.1155/2019/5628160
P932PMC publication ID6633874
P698PubMed publication ID31354826

P50authorXiaojun YanQ89260208
Guoliang XuQ92240633
P2093author name stringYu Chen
Li Jiang
Xue Ding
Peng Nie
Lanbin Yu
Qiyun Zhang
Yanling Xiong
P2860cites workAtherosclerosis — An Inflammatory DiseaseQ26776972
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High-performance liquid chromatographic method for the determination and pharmacokinetic study of wogonoside in rat serum after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoctionQ33238426
Tissue distribution of berberine and its metabolites after oral administration in ratsQ35035856
Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivoQ36269996
Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cellsQ39161746
Inhibition of lipid synthesis through activation of AMP kinase: an additional mechanism for the hypolipidemic effects of berberineQ40310290
Interaction of baicalin with berberine for glucose uptake in 3T3-L1 adipocytes and HepG2 hepatocytesQ42808937
Comparative pharmacokinetics of baicalin in plasma after oral administration of Huang-Lian-Jie-Du-Tang or pure baicalin in MCAO and sham-operated ratsQ43186713
Endothelin-1 induces the expression of C-reactive protein in rat vascular smooth muscle cellsQ43277613
Quality evaluation of commercial Huang-Lian-Jie-Du-Tang based on simultaneous determination of fourteen major chemical constituents using high performance liquid chromatographyQ43940348
Inhibitory effects of Oren-Gedoku-To (Huanglian-Jie-Du-Tang) on free radical-induced lysis of human red blood cellsQ44325239
Novel pharmacokinetic studies of the Chinese formula Huang-Lian-Jie-Du-Tang in MCAO ratsQ44983582
Analysis of alkaloids in Coptis chinensis Franch by accelerated solvent extraction combined with ultra performance liquid chromatographic analysis with photodiode array and tandem mass spectrometry detectionsQ46659456
Antihyperlipidemic effect of crocin isolated from the fructus of Gardenia jasminoides and its metabolite CrocetinQ46792774
Simultaneous determination of berberine and palmatine in rat plasma by HPLC-ESI-MS after oral administration of traditional Chinese medicinal preparation Huang-Lian-Jie-Du decoction and the pharmacokinetic application of the methodQ46808969
Comparative pharmacokinetic investigation on baicalin and wogonoside in type 2 diabetic and normal rats after oral administration of traditional Chinese medicine Huanglian Jiedu decoctionQ47635095
Palmatine inhibits TRIF-dependent NF-κB pathway against inflammation induced by LPS in goat endometrial epithelial cells.Q51123017
Pharmacokinetics of berberine and its main metabolites in conventional and pseudo germ-free rats determined by liquid chromatography/ion trap mass spectrometry.Q51136374
Hypolipidemic Effect and Mechanism of Palmatine from Coptis chinensis in Hamsters Fed High-Fat diet.Q51744997
Chemical profiling and quantification of Chinese medicinal formula Huang-Lian-Jie-Du decoction, a systematic quality control strategy using ultra high performance liquid chromatography combined with hybrid quadrupole-orbitrap and triple quadrupole mQ51772484
Extracts of Scutellariae Radix inhibit low-density lipoprotein oxidation and the lipopolysaccharide-induced macrophage inflammatory response.Q52955782
Role of Inflammation in AtherosclerosisQ58492168
Wogonin suppresses TNF-alpha-induced MMP-9 expression by blocking the NF-kappaB activation via MAPK signaling pathways in human aortic smooth muscle cellsQ79277670
[Qualitative and quantitative determination of the main components of huanglianjiedu decoction by HPLC-UV/MS]Q79952060
Quantitative analysis and chromatographic fingerprinting for the quality evaluation of Scutellaria baicalensis Georgi using capillary electrophoresisQ80311015
Integrated pharmacokinetics of major bioactive components in MCAO rats after oral administration of Huang-Lian-Jie-Du-TangQ83565792
Simultaneous determination of gastrodin and puerarin in rat plasma by HPLC and the application to their interaction on pharmacokineticsQ85893006
[Pharmacodynamics of Huanglian Jiedu decoction in Alzheimer's disease (AD) model rats and effect on improvement of inflammation microenvironment in brain]Q90962465
Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- miceQ91771610
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)5628160
P577publication date2019-07-01
P1433published inInternational Journal of Analytical ChemistryQ22911489
P1476titleSimultaneous Determination of Seven Active Components in Rat Plasma by UHPLC-MS/MS and Application to a Quantitative Study after Oral Administration of Huang-Lian Jie-Du Decoction in High Fat-Induced Atherosclerosis Rats
P478volume2019

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Q92189174Huang-Lian Jie-Du decoction: a review on phytochemical, pharmacological and pharmacokinetic investigationscites workP2860

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