Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF

scientific article published on 24 July 2019

Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12935-019-0914-Y
P932PMC publication ID6657169
P698PubMed publication ID31367190

P50authorYongdong FengQ92323752
P2093author name stringGeng Li
Rongsheng Zhang
Fan Qi
Shengli Shao
P2860cites workMolecular cloning and expression of human hepatocyte growth factorQ24305558
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptorQ24564783
Cancer-Associated Fibroblasts: Their Characteristics and Their Roles in Tumor GrowthQ26774159
Role of cancer-associated fibroblasts in invasion and metastasis of gastric cancerQ26781520
Cancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic PlatformQ28545862
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretionQ29617359
Influence of tumour micro-environment heterogeneity on therapeutic responseQ29617534
CAF-derived HGF promotes cell proliferation and drug resistance by up-regulating the c-Met/PI3K/Akt and GRP78 signalling in ovarian cancer cellsQ33792661
HGF rescues colorectal cancer cells from EGFR inhibition via MET activationQ34550898
Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis modelQ35167775
The c-met/HGF receptor in human tumours.Q35608704
The IL-6-STAT3 axis mediates a reciprocal crosstalk between cancer-derived mesenchymal stem cells and neutrophils to synergistically prompt gastric cancer progressionQ36179636
Tumor microenvironment: the role of the tumor stroma in cancerQ36709404
The biological role of HGF-MET axis in tumor growth and development of metastasisQ36992086
Colon cancer metastasis: MACC1 and Met as metastatic pacemakersQ37576722
CD44: A Multifunctional Cell Surface Adhesion Receptor Is a Regulator of Progression and Metastasis of Cancer CellsQ37683029
CD44, a therapeutic target for metastasising tumoursQ37715272
CD44-shRNA recombinant adenovirus inhibits cell proliferation, invasion, and migration, and promotes apoptosis in HCT116 colon cancer cellsQ38783525
The biology and function of fibroblasts in cancerQ38828825
Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor MicroenvironmentQ38831784
HGF-promoted motility in primary human melanocytes depends on CD44v6 regulated via NF-kappa B, Egr-1, and C/EBP-betaQ39720254
Hepatocyte growth factor enhances adhesion of breast cancer cells to endothelial cells in vitro through up-regulation of CD44.Q40572968
Imbalance of Clara cell-mediated homeostatic inflammation is involved in lung metastasis.Q42746157
Microenvironment-derived HGF overcomes genetically determined sensitivity to anti-MET drugs.Q44843363
Activation of the HGF/c-Met axis in the tumor microenvironment: A multispecies model.Q45991749
Effects of CD44 and E-cadherin overexpression on the proliferation, adhesion and invasion of ovarian cancer cellsQ47155890
FAK, CD44v6, c-Met and EGFR in colorectal cancer parameters: tumour progression, metastasis, patient survival and receptor crosstalkQ47577382
Carcinoma associated fibroblasts derived from oral squamous cell carcinoma promote lymphangiogenesis via c-Met/PI3K/AKT in vitroQ49199965
Cancer-associated fibroblasts promote epithelial-mesenchymal transition and EGFR-TKI resistance of non-small cell lung cancers via HGF/IGF-1/ANXA2 signalingQ49663599
Human colorectal cancer-derived mesenchymal stem cells promote colorectal cancer progression through IL-6/JAK2/STAT3 signalingQ49951562
Regulation of HGF and c-MET Interaction in Normal Ovary and Ovarian Cancer.Q51335207
Cancer-associated fibroblasts induce PDL1+ neutrophils through the IL6-STAT3 pathway that foster immune suppression in hepatocellular carcinoma.Q55324076
IL-6 Mediates Cross-Talk between Tumor Cells and Activated Fibroblasts in the Tumor MicroenvironmentQ89433406
P921main subjectcolorectal cancerQ188874
colorectal carcinomaQ25493920
P304page(s)192
P577publication date2019-07-24
P1433published inCancer Cell InternationalQ1829859
P1476titleHuman colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF
P478volume19

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Q99712027Colorectal Cancer Stem Cells in the Progression to Liver Metastasiscites workP2860

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