Galactosaminoglycans: Medical Applications and Drawbacks

scientific article published on 01 August 2019

Galactosaminoglycans: Medical Applications and Drawbacks is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/MOLECULES24152803
P932PMC publication ID6696379
P698PubMed publication ID31374852

P50authorVitor H PominQ89287076
P2093author name stringBarbara Mulloy
Ariana A Vasconcelos
William P Vignovich
Alysia V Gonzales
P2860cites workChondroitin sulfate proteoglycans in the nervous system: inhibitors to repairQ21284516
FGF-10 and specific structural elements of dermatan sulfate size and sulfation promote maximal keratinocyte migration and cellular proliferationQ24317993
Interaction of the small interstitial proteoglycans biglycan, decorin and fibromodulin with transforming growth factor betaQ24321274
Contaminated heparin associated with adverse clinical events and activation of the contact systemQ24619723
Targeting selectins and selectin ligands in inflammation and cancerQ24658204
Holothurian fucosylated chondroitin sulfateQ27015773
The Structure of a Chondroitin Sulfate-binding Domain Important in Placental MalariaQ27650818
Dermatan sulfate: new functions from an old glycosaminoglycanQ28221133
Pathogenicity of human anti-platelet factor 4 (PF4)/heparin in vivo: generation of mouse anti-PF4/heparin and induction of thrombocytopenia by heparinQ28378937
6B4 proteoglycan/phosphacan, an extracellular variant of receptor-like protein-tyrosine phosphatase zeta/RPTPbeta, binds pleiotrophin/heparin-binding growth-associated molecule (HB-GAM)Q28565680
A chondroitin sulfate proteoglycan PTPzeta /RPTPbeta regulates the morphogenesis of Purkinje cell dendrites in the developing cerebellumQ28584222
Antithrombin activity and disaccharide composition of dermatan sulfate from different bovine tissuesQ33312192
Marine sulfated glycans with serpin-unrelated anticoagulant propertiesQ33358325
Increased prevalence of antiheparin platelet factor 4 antibodies in patients may be due to contaminated heparinQ33384050
Review: contaminants in heparin: review of the literature, molecular profiling, and clinical implications.Q33393960
Dermatan sulfate: an alternative to unfractionated heparin for anticoagulation in hemodialysis patientsQ33400253
Chondroitin sulfate proteoglycans regulate the growth, differentiation and migration of multipotent neural precursor cells through the integrin signaling pathwayQ33511675
Identification of chondroitin sulfate E proteoglycans and heparin proteoglycans in the secretory granules of human lung mast cellsQ33564244
Fucosylated chondroitin sulfate inhibits Plasmodium falciparum cytoadhesion and merozoite invasion.Q33622909
Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition ofQ72626713
Preparation and structural determination of dermatan sulfate-derived oligosaccharidesQ73075426
Structure of fucose branches in the glycosaminoglycan from the body wall of the sea cucumber Stichopus japonicusQ73131482
Depolymerized holothurian glycosaminoglycan (DHG) prevents neointimal formation in balloon-injured rat carotid arteryQ73153527
A novel pentasaccharide sequence GlcA(3-sulfate)(beta1-3)GalNAc(4-sulfate)(beta1-4)(Fuc alpha1-3)GlcA(beta1-3)GalNAc(4-sulfate) in the oligosaccharides isolated from king crab cartilage chondroitin sulfate K and its differential susceptibility to chQ73202291
The anticoagulant and hemorrhagic effects of DHG, a new depolymerized holothurian glycosaminoglycan, on experimental hemodialysis in dogsQ73553860
Heparan sulfate chains from glypican and syndecans bind the Hep II domain of fibronectin similarly despite minor structural differencesQ73586120
Anticoagulant and antithrombin effects of intimatan, a heparin cofactor II agonistQ74272184
Neuronal cell adhesion, mediated by the heparin-binding neuroregulatory factor midkine, is specifically inhibited by chondroitin sulfate E. Structural ans functional implications of the over-sulfated chondroitin sulfateQ74291012
Selective and sustained inhibition of surface-bound thrombin activity by intimatan/heparin cofactor II and its relevance to assessing systemic anticoagulation in vivo, ex vivo and in vitroQ74586215
Antithrombotic activity of a fucosylated chondroitin sulphate from echinoderm: sulphated fucose branches on the polysaccharide account for its antithrombotic actionQ74800874
Characterization of a neutrophil cell surface glycosaminoglycan that mediates binding of platelet factor 4Q77353640
Fucosylated chondroitin sulfate as a new oral antithrombotic agentQ79397768
Selectin blocking activity of a fucosylated chondroitin sulfate glycosaminoglycan from sea cucumber. Effect on tumor metastasis and neutrophil recruitmentQ79984417
Dermatan disulfate (Intimatan) prevents complement-mediated myocardial injury in the human-plasma-perfused rabbit heartQ81277934
Biochemical and immunohistochemical analysis of glycosaminoglycans in inflamed and non-inflamed intestinal mucosa of patients with Crohn's diseaseQ81297178
Effects of antithrombin and heparin cofactor II levels on anticoagulation with IntimatanQ81443643
Intimatan (dermatan 4,6-O-disulfate) prevents rethrombosis after successful thrombolysis in the canine model of deep vessel wall injuryQ81746823
Serpin-independent anticoagulant activity of a fucosylated chondroitin sulfateQ81920488
Contaminated heparin preparations, severe adverse events and the contact systemQ82059532
Keratan sulfate restricts neural plasticity after spinal cord injuryQ82665689
Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharidesQ83949098
Residual keratan sulfate in chondroitin sulfate formulations for oral administrationQ84641715
CLINICAL PRACTICE. Heparin-Induced ThrombocytopeniaQ85598285
Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor XaseQ86455056
Structure and biological activity of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria japonicaQ86935245
Plasma contact activation by a fucosylated chondroitin sulfate and its structure-activity relationship studyQ90281980
Fucosylated chondroitin sulfates from the sea cucumbers Holothuria tubulosa and Holothuria stellatiQ91274576
Interaction between histidine-rich glycoprotein and platelet factor 4 with dermatan sulfate and low-molecular-weight dermatan sulfateQ47419242
Keratan Sulphate, a complex Glycosaminoglycan with Unique Functional CapabilityQ47860795
Glycosaminoglycan-protein interactions: definition of consensus sites in glycosaminoglycan binding proteinsQ47958114
Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cellsQ48124371
Separation, purification, structures and anticoagulant activities of fucosylated chondroitin sulfates from Holothuria scabraQ49646347
Specificity of glycosaminoglycan-protein interactionsQ49894342
2,3-Di-O-sulfo glucuronic acid: An unmodified and unusual residue in a highly sulfated chondroitin sulfate from Litopenaeus vannamei.Q49903394
Unbalanced effects of dermatan sulfates with different sulfation patterns on coagulation, thrombosis and bleedingQ50106129
Effects of polysaccharides enriched in 2,4-disulfated fucose units on coagulation, thrombosis and bleeding. Practical and conceptual implications.Q50297103
Effect of Chondroitin Sulphate on Pro-Inflammatory Mediators and Disease Activity in Patients with Inflammatory Bowel Disease.Q50436943
Platelet Factor 4 Binds to Vascular Proteoglycans and Controls Both Growth Factor Activities and Platelet Activation.Q51032187
A highly regular fucosylated chondroitin sulfate from the sea cucumber Massinium magnum: Structure and effects on coagulation.Q51040318
Sulfation pattern of fucose branches affects the anti-hyperlipidemic activities of fucosylated chondroitin sulfate.Q51332075
Protective effects of systemic dermatan sulfate treatment in a preclinical model of radiation-induced oral mucositis.Q51745450
A characteristic chondroitin sulfate trisaccharide unit with a sulfated fucose branch exhibits neurite outgrowth-promoting activity: Novel biological roles of fucosylated chondroitin sulfates isolated from the sea cucumber Apostichopus japonicus.Q52097113
Inhibition and enhancement of neural regeneration by chondroitin sulfate proteoglycans.Q39374452
From Farm to Pharma: An Overview of Industrial Heparin Manufacturing MethodsQ39387837
The role of human natural killer-1 (HNK-1) carbohydrate in neuronal plasticity and diseaseQ39435938
Structural characterization of fucosylated chondroitin sulfates from sea cucumbers Apostichopus japonicus and Actinopyga mauritiana.Q39453677
Ascidian dermatan sulfates attenuate metastasis, inflammation and thrombosis by inhibition of P-selectin.Q39524033
Combined Treatment With Chondroitin Sulfate and Glucosamine Sulfate Shows No Superiority Over Placebo for Reduction of Joint Pain and Functional Impairment in Patients With Knee Osteoarthritis: A Six-Month Multicenter, Randomized, Double-Blind, PlacQ39539742
Heparin crisis 2008: a tipping point for increased FDA enforcement in the pharma sector?Q39913740
Depolymerized holothurian glycosaminoglycan and heparin inhibit the intrinsic tenase complex by a common antithrombin-independent mechanismQ40284089
Antiviral activity of chondroitin sulphate E targeting dengue virus envelope proteinQ40348272
Dermatan sulfate as a potential therapeutic agentQ40550054
Dermatan sulfate exerts an enhanced growth factor response on skeletal muscle satellite cell proliferation and migrationQ40619052
Dermatan sulfate binds and potentiates activity of keratinocyte growth factor (FGF-7).Q40705979
Distinct structures of the α-fucose branches in fucosylated chondroitin sulfates do not affect their anticoagulant activity.Q40818091
Medical Gains of Chondroitin Sulfate Upon FucosylationQ40912959
The family of the small leucine-rich proteoglycans: key regulators of matrix assembly and cellular growthQ41465984
Binding of urinary protein C inhibitor to cultured human epithelial kidney tumor cells (TCL-598). The role of glycosaminoglycans present on the luminal cell surfaceQ41467314
Distinct selectin ligands on colon carcinoma mucins can mediate pathological interactions among platelets, leukocytes, and endotheliumQ41683514
Role of glycosaminoglycans in the regulation of T cell proliferation induced by thymic stroma-derived T cell growth factorQ41687540
Chondroitinase ABC digestion of dermatan sulphate. N.m.r. spectroscopic characterization of the oligo- and poly-saccharidesQ42008547
Identification of keratan sulfate disaccharide at C-3 position of glucuronate of chondroitin sulfate from Mactra chinensisQ42155645
Heparin therapy for stroke: hemorrhagic complications and risk factors for intracerebral hemorrhageQ42251572
The Sea as a Rich Source of Structurally Unique Glycosaminoglycans and MimeticsQ42366909
Cerebral Hemorrhage Complicating Heparin-induced Thrombocytopenia after Percutaneous Coronary Intervention: A Clinical Dilemma of Medical TreatmentQ42538047
Novel sulfated oligosaccharides containing 3-O-sulfated glucuronic acid from king crab cartilage chondroitin sulfate K. Unexpected degradation by chondroitinase ABC.Q42643132
Characteristic hexasaccharide sequences in octasaccharides derived from shark cartilage chondroitin sulfate D with a neurite outgrowth promoting activity.Q42671875
Evolution of glycosaminoglycans: Comparative biochemical study.Q42741712
1H-n.m.r. investigation of naturally occurring and chemically oversulphated dermatan sulphates. Identification of minor monosaccharide residuesQ42794083
Fucosylated chondroitin sulfate attenuates renal fibrosis in animals submitted to unilateral ureteral obstruction: a P-selectin-mediated event?Q42879490
N-acetylglucosamine 6-O-sulfotransferase-1-deficient mice show better functional recovery after spinal cord injury.Q43081631
Inactivation of thrombin by a fucosylated chondroitin sulfate from echinodermQ43588777
Structural features of dermatan sulfates and their relationship to anticoagulant and antithrombotic activitiesQ43617920
Fucosylated chondroitin sulfate from Acaudina molpadioides improves hyperglycemia via activation of PKB/GLUT4 signaling in skeletal muscle of insulin resistant miceQ43636050
Structure of a fucose-branched chondroitin sulfate from sea cucumber. Evidence for the presence of 3-O-sulfo-beta-D-glucuronosyl residuesQ43663568
Detection of keratan sulfate by immunological methods in commercial chondroitin sulfate preparationsQ43700679
Characterization of currently marketed heparin products: adverse event relevant bioassaysQ43717471
Sulfation pattern of the fucose branch is important for the anticoagulant and antithrombotic activities of fucosylated chondroitin sulfates.Q43922680
Intimatan prevents arterial and venous thrombosis in a canine model of deep vessel wall injuryQ44002381
Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner in the brain and other tissuesQ44131360
A fucosylated chondroitin sulfate from echinoderm modulates in vitro fibroblast growth factor 2-dependent angiogenesis.Q44259046
Depolymerized holothurian glycosaminoglycan (DHG), a novel alternative anticoagulant for hemodialysis, is safe and effective in a dog renal failure modelQ44358780
Fractions of chemically oversulphated galactosaminoglycan sulphates inhibit three enveloped viruses: human immunodeficiency virus type 1, herpes simplex virus type 1 and human cytomegalovirusQ44466925
Glycosaminoglycan and proteoglycan inhibit the depolymerization of beta2-microglobulin amyloid fibrils in vitroQ44545061
Chondroitin sulfate proteoglycans are required for lung growth and morphogenesis in vitroQ44552011
Modulation of native chondroitin sulphate structure in tissue development and in diseaseQ44706510
Two fucosylated chondroitin sulfates from the sea cucumber Eupentacta fraudatrixQ46400237
Characterization and anticoagulant activity of a fucosylated chondroitin sulfate with unusually procoagulant effect from sea cucumberQ46962901
Fucosylated chondroitin sulfate oligosaccharides exert anticoagulant activity by targeting at intrinsic tenase complex with low FXII activation: Importance of sulfation pattern and molecular sizeQ47194797
A novel structural fucosylated chondroitin sulfate from Holothuria Mexicana and its effects on growth factors binding and anticoagulationQ47238270
Borrelia burgdorferi glycosaminoglycan-binding proteins: a potential target for new therapeutics against Lyme diseaseQ47370006
Low molecular weight dermatan sulfate as an antithrombotic agent. Structure-activity relationship studiesQ47377923
Synthetic Oligosaccharide Libraries and Microarray Technology: A Powerful Combination for the Success of Current Glycosaminoglycan InteractomicsQ47379826
The human pharmacokinetics of oral ingestion of glucosamine and chondroitin sulfate taken separately or in combinationQ33679221
Understanding Dermatan Sulfate-Heparin Cofactor II Interaction through Virtual Library ScreeningQ33690582
Chondroitin Sulfate-Rich Extract of Skate Cartilage Attenuates Lipopolysaccharide-Induced Liver Damage in Mice.Q33833408
Characterization of glycosaminoglycans by 15N NMR spectroscopy and in vivo isotopic labelingQ33909062
Distribution of sulfated glycosaminoglycans in the animal kingdom: widespread occurrence of heparin-like compounds in invertebratesQ33911458
Chondroitin sulfate-E is a negative regulator of a pro-tumorigenic Wnt/beta-catenin-Collagen 1 axis in breast cancer cellsQ33999637
Chemically oversulfated glycosaminoglycans are potent modulators of contact system activation and different cell signaling pathwaysQ34003880
Biosynthesis of chondroitin/dermatan sulfateQ34168651
Recent advances in the structural biology of chondroitin sulfate and dermatan sulfateQ34271235
Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activityQ34317336
Inter-alpha-trypsin inhibitor, a covalent protein-glycosaminoglycan-protein complexQ34321775
Antithrombotic activity of dermatan sulfate in heparin cofactor II-deficient miceQ34341743
The pharmacokinetics and pharmacodynamics of dermatan sulphate MF701 during haemodialysis for chronic renal failureQ34403775
Glycomics Hits the Big TimeQ34432774
Dermatan sulfate released after injury is a potent promoter of fibroblast growth factor-2 function.Q34475404
The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesisQ34506615
Holothurian glycosaminoglycan inhibits metastasis and thrombosis via targeting of nuclear factor-κB/tissue factor/Factor Xa pathway in melanoma B16F10 cellsQ34598936
Structure and anticoagulant properties of sulfated glycosaminoglycans from primitive Chordates.Q34605048
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical eventsQ34774203
The role of sulfoglucuronosyl glycosphingolipids in the pathogenesis of monoclonal IgM paraproteinemia and peripheral neuropathyQ35208842
The protective role of fucosylated chondroitin sulfate, a distinct glycosaminoglycan, in a murine model of streptozotocin-induced diabetic nephropathyQ35239936
Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cellsQ35558089
Interactions of the Chemokine CCL5/RANTES with Medium-Sized Chondroitin Sulfate LigandsQ35685184
Structural and conformational aspects of the anticoagulant and anti-thrombotic activity of heparin and dermatan sulfateQ35743476
Effectiveness and safety of Glucosamine, chondroitin, the two in combination, or celecoxib in the treatment of osteoarthritis of the knee.Q35844016
Discovery of an intrinsic tenase complex inhibitor: Pure nonasaccharide from fucosylated glycosaminoglycanQ35845738
Dermatan sulfate is involved in the tumorigenic properties of esophagus squamous cell carcinomaQ35894756
Sugar-coating wound repair: a review of FGF-10 and dermatan sulfate in wound healing and their potential application in burn woundsQ35947477
Chondroitin sulfate proteoglycans in neural development and regeneration.Q36049261
Chondroitin sulfate in the treatment of osteoarthritis: from in vitro studies to clinical recommendations.Q36059429
Lessons learned from the contamination of heparinQ36399734
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxibQ36475626
Therapeutic value of glycosaminoglycans in cancerQ36598106
Intracerebral hemorrhage in stroke patients anticoagulated with heparinQ38718635
Dual and antagonic therapeutic effects of sulfated glycansQ38835664
Chondroitin sulphate: a focus on osteoarthritisQ38838064
The structure of a fucosylated chondroitin sulfate from the sea cucumber Cucumaria frondosaQ38864137
Occurrence of sulfated fucose branches in fucosylated chondroitin sulfate are essential for the polysaccharide effect preventing muscle damage induced by toxins and crude venom from Bothrops jararacussu snakeQ39036740
Chondroitin sulfate (CS) lyases: Structure, function and application in therapeuticsQ39066124
The depolymerized fucosylated chondroitin sulfate from sea cucumber potently inhibits HIV replication via interfering with virus entryQ39107593
Anti-HIV-1 activity and structure-activity-relationship study of a fucosylated glycosaminoglycan from an echinoderm by targeting the conserved CD4 induced epitopeQ39139323
Distribution of sulfated mucopolysaccharides in invertebratesQ39140533
Functional chondroitin sulfate from Enteroctopus dofleini containing a 3-O-sulfo glucuronic acid residue.Q52148586
Heparin cofactor II is regulated allosterically and not primarily by template effects. Studies with mutant thrombins and glycosaminoglycans.Q52510803
Two structurally similar fucosylated chondroitin sulfates from the holothurian species Stichopus chloronotus and Stichopus horrens.Q52630214
The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system.Q52679512
Dermatan sulfate reduces monocyte chemoattractant protein 1 and TGF-β production, as well as macrophage recruitment and myofibroblast accumulation in mice with unilateral ureteral obstruction.Q53226588
Biosynthesis of the escherichia coli K4 capsule polysaccharide. A parallel system for studies of glycosyltransferases in chondroitin formation.Q54571908
Glycosaminoglycans and Proteoglycans.Q54995051
Radioprotective Effects of Dermatan Sulfate in a Preclinical Model of Oral Mucositis-Targeting Inflammation, Hypoxia and Junction Proteins without Stimulating Proliferation.Q55656164
Highly Sulfated Dermatan Sulfates from AscidiansQ57268109
Quantitation of Dermatan Sulfate Active Site for Heparin Cofactor II by 1H Nuclear Magnetic Resonance SpectroscopyQ57563867
Presentation of IFN- to Nitric Oxide-Producing Cells: A Novel Function for Mast CellsQ58377548
Structure and Anti-Inflammatory Activity of a New Unusual Fucosylated Chondroitin Sulfate fromQ58546545
Harnessing chondroitin sulphate in composite scaffolds to direct progenitor and stem cell function for tissue repairQ58824761
Modulation of vascular human endothelial and rat smooth muscle cell growth by a fucosylated chondroitin sulfate from echinodermQ63944705
Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trialsQ64137153
Chondroitin Sulfate Safety and QualityQ64253125
Glucose branches in chondroitin sulfates from squid cartilageQ67586611
Dermatan sulphate: A safe approach to prevention of postoperative deep vein thrombosisQ68166937
Primary mesenchyme cell migration requires a chondroitin sulfate/dermatan sulfate proteoglycanQ68190079
A new dermatan polysulfate, chondroitin sulfate H, from hagfish notochordQ68473135
A novel dermatan polysulfate from hagfish skin, containing trisulfated disaccharide residuesQ68490809
Structural differences of dermatan sulfates from different originsQ69485403
The haemorrhagic and antithrombotic effects of dermatan sulphateQ69658587
Heparin induced bleedingQ70376772
Occurrence of a unique fucose-branched chondroitin sulfate in the body wall of a sea cucumberQ70411706
Activation of heparin cofactor II by heparin and dermatan sulfateQ70815256
A unique dermatan sulfate-like glycosaminoglycan from ascidian. Its structure and the effect of its unusual sulfation pattern on anticoagulant activityQ70825897
Structure and anticoagulant activity of a fucosylated chondroitin sulfate from echinoderm. Sulfated fucose branches on the polysaccharide account for its high anticoagulant actionQ71514914
Culture from mouse bone marrow of a subclass of mast cells possessing a distinct chondroitin sulfate proteoglycan with glycosaminoglycans rich in N-acetylgalactosamine-4,6-disulfateQ71606321
Determination of the HNK-1 epitope (3-sulphated glucuronic acid) in intact chondroitin sulphates by ELISA. Application to squid skin proteoglycans and their oversulphated carbohydrate structuresQ71633824
High affinity of a fucosylated chondroitin sulfate for plasma low density lipoproteinQ71746465
Relative influence of different disulphate disaccharide clusters on the HCII-mediated inhibition of thrombin by dermatan sulphates of different originsQ72202483
Acidic polysaccharides of the ascidian Styela plicata. Biosynthetic studies on the sulfated L-galactans of the tunic, and preliminary characterization of a dermatan sulfate-like polymer in body tissuesQ72371605
Emergence and structural characteristics of chondroitin sulfates in the animal kingdomQ36713846
Role of the sulfation pattern of chondroitin sulfate in its biological activities and in the binding of growth factorsQ36713851
Comparison of physicochemical characteristics and anticoagulant activities of polysaccharides from three sea cucumbersQ36806702
Chondroitin/dermatan sulfate in the central nervous systemQ36967533
Chondroitin sulfate, hyaluronic acid and chitin/chitosan production using marine waste sources: characteristics, applications and eco-friendly processes: a review.Q36994144
Sulfation of the bikunin chondroitin sulfate chain determines heavy chain·hyaluronan complex formationQ37095368
Inhibitors of selectin functions in the treatment of inflammatory skin disorders.Q37116804
Potential effects of chondroitin sulfate on joint swelling: a GAIT reportQ37167150
The biological role of chondroitin sulfate in cancer and chondroitin-based anticancer agentsQ37210375
Recent advances in the structural study of functional chondroitin sulfate and dermatan sulfate in health and diseaseQ37228522
Anti-inflammatory activity of chondroitin sulfateQ37230656
Immunomodulatory and anti-inflammatory effects of chondroitin sulphateQ37310621
Potential therapeutic application of chondroitin sulfate/dermatan sulfateQ37347125
Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exositeQ37373064
Quality of different chondroitin sulfate preparations in relation to their therapeutic activityQ37611121
Modulation of inflammation by chondroitin sulfateQ37732933
Vascular Dermatan Sulfate and Heparin Cofactor IIQ37784316
Anti-inflammatory activity of chondroitin sulphate: new functions from an old natural macromoleculeQ37951364
Glycosaminoglycans: key players in cancer cell biology and treatmentQ37983930
Case study: contamination of heparin with oversulfated chondroitin sulfateQ38008265
Anticoagulant motifs of marine sulfated glycansQ38212639
Fucosylated chondroitin sulfate diversity in sea cucumbers: a reviewQ38240498
Oversulfated chondroitin/dermatan sulfates containing GlcAbeta1/IdoAalpha1-3GalNAc(4,6-O-disulfate) interact with L- and P-selectin and chemokinesQ38292486
Isolation and structural determination of novel sulfated hexasaccharides from squid cartilage chondroitin sulfate E that exhibits neuroregulatory activitiesQ38295796
The binding of chondroitin sulfate to pleiotrophin/heparin-binding growth-associated molecule is regulated by chain length and oversulfated structuresQ38317418
Chondroitin sulfate characterized by the E-disaccharide unit is a potent inhibitor of herpes simplex virus infectivity and provides the virus binding sites on gro2C cellsQ38323484
Structure of a dermatan sulfate hexasaccharide that binds to heparin cofactor II with high affinityQ38338617
Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.Q38339525
Molecular size of dermatan sulfate oligosaccharides required to bind and activate heparin cofactor II.Q38350746
Heterogeneity of the chondroitin sulfate portion of phosphacan/6B4 proteoglycan regulates its binding affinity for pleiotrophin/heparin binding growth-associated molecule.Q38352991
Discrepancies in composition and biological effects of different formulations of chondroitin sulfate.Q38371965
Antimicrobial Sulfated Glycans: Structure and FunctionQ38516688
A Dilemma in the Glycosaminoglycan-Based Therapy: Synthetic or Naturally Unique Molecules?Q38543731
Autoimmune heparin-induced thrombocytopeniaQ38605630
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue15
P921main subjectarthralgiaQ683498
P577publication date2019-08-01
P1433published inMoleculesQ151332
P1476titleGalactosaminoglycans: Medical Applications and Drawbacks
P478volume24

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