The HSP90/Akt pathway may mediate artemether-induced apoptosis of Cal27 cells

scientific article published on 30 August 2019

The HSP90/Akt pathway may mediate artemether-induced apoptosis of Cal27 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/2211-5463.12711
P932PMC publication ID6768108
P698PubMed publication ID31376209

P50authorYongwen HeQ92380659
P2093author name stringLei Li
Jianhua Wu
Yiting Wang
Ken Lin
Xiaobin Ren
P2860cites workExperimental Therapy of Hepatoma with Artemisinin and Its Derivatives: In vitro and In vivo Activity, Chemosensitization, and Mechanisms of ActionQ22061792
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Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cellsQ34674201
Elevated expression of HSP90 and the antitumor effect of an HSP90 inhibitor via inactivation of the Akt/mTOR pathway in undifferentiated pleomorphic sarcomaQ35821721
Comparative cytotoxicity of artemisinin and cisplatin and their interactions with chlorogenic acids in MCF7 breast cancer cellsQ35863615
Metastasis of squamous cell carcinoma of the oral tongueQ36928038
Anticancer properties of artemisinin derivatives and their targeted delivery by transferrin conjugationQ36973937
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Heat shock protein 90/Akt pathway participates in the cardioprotective effect of exogenous hydrogen sulfide against high glucose-induced injury to H9c2 cells.Q38716234
Artemisinin inhibits inflammatory response via regulating NF-κB and MAPK signaling pathwaysQ38725091
Dihydroartemisinin exhibits antitumor activity toward hepatocellular carcinoma in vitro and in vivo.Q39395227
SNX-2112, an Hsp90 inhibitor, induces apoptosis and autophagy via degradation of Hsp90 client proteins in human melanoma A-375 cellsQ39425655
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Squamous cell carcinoma of oral tongue in young patients - A 10 years tertiary care experienceQ40051049
The heat-shock protein 90 inhibitor, geldanamycin, induces apoptotic cell death in Epstein-Barr virus-positive NK/T-cell lymphoma by Akt down-regulationQ40085734
Artemether Regulates Chemosensitivity to Doxorubicin via Regulation of B7-H3 in Human Neuroblastoma CellsQ41248541
Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cellsQ43016565
Never-smokers, never-drinkers: unique clinical subgroup of young patients with head and neck squamous cell cancersQ43289833
Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalphaQ43759225
Caspase-3 activation induced by inhibition of mitochondrial complex I is facilitated by glycogen synthase kinase-3beta and attenuated by lithiumQ43786473
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3β, and induction of the mitochondrial-dependent intrinsic caspase pathwayQ44400926
Artemether suppresses cell proliferation and induces apoptosis in diffuse large B cell lymphoma cellsQ45722328
Western-medicine-validated anti-tumor agents and traditional Chinese medicineQ47732460
Genetic polymorphisms of the multidrug resistance 1 gene MDR1 and the risk of hepatocellular carcinoma.Q53220952
CRBP-1 over-expression is associated with poor prognosis in tongue squamous cell carcinoma.Q55200843
Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy.Q55467815
Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivoQ84717431
P433issue10
P304page(s)1726-1733
P577publication date2019-08-30
P1433published inFEBS Open BioQ27724062
P1476titleThe HSP90/Akt pathway may mediate artemether-induced apoptosis of Cal27 cells
P478volume9