Molecular targeted therapy-related life-threatening toxicity in patients with malignancies. A systematic review of published cases

scientific article published on 29 May 2019

Molecular targeted therapy-related life-threatening toxicity in patients with malignancies. A systematic review of published cases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1007/S00134-019-05650-W
P932PMC publication ID7095151
P698PubMed publication ID31143997

P50authorElie AzoulayQ42222310
P2093author name stringVirginie Lemiale
Sandra Assoun
P2860cites workImproved survival with vemurafenib in melanoma with BRAF V600E mutationQ24631953
Immune related adverse events associated with anti-CTLA-4 antibodies: systematic review and meta-analysisQ26785746
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.Q27824766
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancerQ27824847
Cetuximab for the treatment of colorectal cancer.Q27851419
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trialQ27851578
Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancerQ27851691
Combined vemurafenib and cobimetinib in BRAF-mutated melanomaQ27853076
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinomaQ27860881
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancerQ28240089
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancerQ28278736
Sunitinib versus interferon alfa in metastatic renal-cell carcinomaQ28282757
Sorafenib in advanced clear-cell renal-cell carcinomaQ28282767
The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab networkQ28485085
Adverse Events Associated with Immune Checkpoint Blockade in Patients with Cancer: A Systematic Review of Case ReportsQ28553328
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFRQ29547545
Ipilimumab as a Cause of Severe Pan-Colitis and Colonic PerforationQ42255119
Erratum: Severe acute interstitial nephritis after combination immune-checkpoint inhibitor therapy for metastatic melanoma.Q42407939
Ipilimumab-induced perforating colitisQ43532238
Gefitinib versus docetaxel in previously treated non-small-cell lung cancer (INTEREST): a randomised phase III trial.Q46232500
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinomaQ46329140
Bevacizumab plus radiotherapy-temozolomide for newly diagnosed glioblastomaQ46796397
Global surveillance of trends in cancer survival 2000-14 (CONCORD-3): analysis of individual records for 37 513 025 patients diagnosed with one of 18 cancers from 322 population-based registries in 71 countries.Q48507831
Pneumocystis jirovecii pneumonia in everolimus-treated renal cell carcinoma.Q54367805
Bevacizumab in Combination With Oxaliplatin, Fluorouracil, and Leucovorin (FOLFOX4) for Previously Treated Metastatic Colorectal Cancer: Results From the Eastern Cooperative Oncology Group Study E3200Q56679480
Fatal Toxic Effects Associated With Immune Checkpoint Inhibitors: A Systematic Review and Meta-analysisQ56888890
Multiple colon perforation as a fatal complication during treatment of metastatic melanoma with ipilimumab - case reportQ56897082
Resolution of Severe Ipilimumab-Induced Hepatitis After Antithymocyte Globulin TherapyQ58024768
Myasthenia gravis associated with ipilimumab and nivolumab in the treatment of small cell lung cancerQ86902269
Liver transplantation treating the patient with hepatic failure associated with sorafenib treatment: report of a caseQ87233533
Severe inflammatory ileitis resulting in ileal perforation in association with combination immune checkpoint blockade for metastatic malignant melanomaQ88286896
Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upQ89148986
Erlotinib in previously treated non-small-cell lung cancerQ29547546
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerQ29614302
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated MelanomaQ29615443
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trialQ29618031
Pembrolizumab versus Ipilimumab in Advanced MelanomaQ29618134
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
Nivolumab and ipilimumab versus ipilimumab in untreated melanomaQ29620657
Everolimus in postmenopausal hormone-receptor-positive advanced breast cancerQ29620676
Nivolumab in previously untreated melanoma without BRAF mutationQ29620688
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung CancerQ29620902
Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung CancerQ29620913
Platinum-based chemotherapy plus cetuximab in head and neck cancerQ33381094
Improved survival with bevacizumab in advanced cervical cancerQ33566222
A phase 3 trial of bevacizumab in ovarian cancerQ34030022
Interesting possibilities to improve the safety and efficacy of ipilimumab (Yervoy).Q34232474
Everolimus for advanced pancreatic neuroendocrine tumors.Q34399809
Initial therapy with FOLFOXIRI and bevacizumab for metastatic colorectal cancer.Q34444495
Combination immunotherapy: a road map.Q34552128
Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, dose-ranging studyQ34614776
Review: side effects of approved molecular targeted therapies in solid cancers.Q34731665
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAilQ34935734
Anti-PD-1-Related Pneumonitis during Cancer ImmunotherapyQ35965389
Fulminant Myocarditis with Combination Immune Checkpoint BlockadeQ37595462
Management of immune-related adverse events and kinetics of response with ipilimumabQ38012057
Molecular-targeted agents combination therapy for cancer: developments and potentialsQ38104670
Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 studyQ38245038
Survival in solid cancer patients following intensive care unit admission.Q38249876
A systematic review of immune-related adverse event reporting in clinical trials of immune checkpoint inhibitors.Q38427448
Management of toxicities of immune checkpoint inhibitors.Q38732543
Comprehensive Meta-analysis of Key Immune-Related Adverse Events from CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients.Q38752269
Managing Adverse Events With Immune Checkpoint AgentsQ38816844
Immune checkpoint inhibitors in challenging populationsQ38939708
Cardiovascular Toxic Effects of Targeted Cancer TherapiesQ38978969
Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant TherapyQ39311439
P433issue7
P304page(s)988-997
P577publication date2019-05-29
P1433published inIntensive Care MedicineQ15749164
P1476titleMolecular targeted therapy-related life-threatening toxicity in patients with malignancies. A systematic review of published cases
P478volume45

Search more.