Structures of STING protein illuminate this key regulator of inflammation

scientific article published on 01 March 2019

Structures of STING protein illuminate this key regulator of inflammation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/D41586-019-00707-8
P698PubMed publication ID30880329

P50authorAndrea AblasserQ15990466
P2860cites workCryo-EM structures of STING reveal its mechanism of activation by cyclic GMP-AMPQ92179881
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathwayQ24306635
STING: infection, inflammation and cancerQ26776009
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNAQ28118718
Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activationQ28256216
Activated STING in a vascular and pulmonary syndromeQ34241214
Autoimmunity initiates in nonhematopoietic cells and progresses via lymphocytes in an interferon-dependent autoimmune diseaseQ35717955
STING Activation by Translocation from the ER Is Associated with Infection and Autoinflammatory DiseaseQ35956285
Inflammation-driven carcinogenesis is mediated through STINGQ37207341
How cryo-EM is revolutionizing structural biologyQ38301962
Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.Q39235226
Targeting STING with covalent small-molecule inhibitorsQ59059814
Parkin and PINK1 mitigate STING-induced inflammationQ59093291
Structural basis of STING binding with and phosphorylation by TBK1Q92179849
P433issue7748
P407language of work or nameEnglishQ1860
P921main subjectbites and stingsQ54911704
P304page(s)321-322
P577publication date2019-03-01
P1433published inNatureQ180445
P1476titleStructures of STING protein illuminate this key regulator of inflammation
P478volume567

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Q90426403Canadian Cannabis Consumption and Patterns of Congenital Anomalies: An Ecological Geospatial Analysiscites workP2860

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