Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias

scientific article published on 20 May 2019

Pilot study of mitochondrial bioenergetics in subjects with acute porphyrias is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YMGME.2019.05.010
P932PMC publication ID6864263
P698PubMed publication ID31153822

P2093author name stringTing Li
Herbert L Bonkovsky
Natalia Dixon
Anthony Molina
Brandon Marion
Denise Faust
Sean Rudnick
Stephen Dozier
P2860cites workMitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression.Q30582601
Decline in skeletal muscle mitochondrial function with aging in humansQ33936772
Recommendations for the diagnosis and treatment of the acute porphyriasQ33985744
Iron deficiency and iron excess damage mitochondria and mitochondrial DNA in rats.Q34013010
Mitochondrial DNA copy number in peripheral blood cells declines with age and is associated with general health among elderly.Q34022817
Heme deficiency may be a factor in the mitochondrial and neuronal decay of agingQ34379668
Assays for Porphyrins, δ-Aminolevulinic-Acid Dehydratase, and Porphyrinogen Synthetase in Microliter Samples of Whole Blood: Applications to Metabolic Defects Involving the Heme PathwayQ34724671
Clinically important features of porphyrin and heme metabolism and the porphyriasQ34785744
Assessing mitochondrial dysfunction in cells.Q34793639
Acute porphyrias in the USA: features of 108 subjects from porphyrias consortiumQ36040689
Decreased Bioenergetic Health Index in monocytes isolated from the pericardial fluid and blood of post-operative cardiac surgery patientsQ36185222
Respirometric Profiling of Muscle Mitochondria and Blood Cells Are Associated With Differences in Gait Speed Among Community-Dwelling Older AdultsQ36515886
Pitfalls in Erythrocyte Protoporphyrin Measurement for Diagnosis and Monitoring of ProtoporphyriasQ36554163
Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human bloodQ36906968
Simultaneous quantification of mitochondrial DNA copy number and deletion ratio: a multiplex real-time PCR assayQ36972506
Mitochondrial DNA injury and mortality in hemodialysis patientsQ37042150
Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial healthQ37302239
A Microassay for Uroporphyrinogen I Synthase, One of Three Abnormal Enzyme Activities in Acute Intermittent Porphyria, and its Application to the Study of the Genetics of this DiseaseQ37433776
Acute PorphyriasQ38544594
Blood-cell bioenergetics are associated with physical function and inflammation in overweight/obese older adults.Q38979433
Mitochondrial energetic defects in muscle and brain of a Hmbs-/- mouse model of acute intermittent porphyriaQ42478276
A Method for the Localization of Sites for Oxidative PhosphorylationQ59054182
A Simple and Rapid Assay of Oxidative PhosphorylationQ59068452
Acute intermittent porphyria causes hepatic mitochondrial energetic failure in a mouse modelQ59590280
A plasma porphyrin fluorescence marker for variegate porphyriaQ71204636
Accumulation of porphyrins in plasma and tissues of dogs after delta-aminolevulinic acid administration: implications for photodynamic therapyQ71623066
Effects of aging on mitochondrial DNA copy number and cytochrome c oxidase gene expression in rat skeletal muscle, liver, and heartQ73396535
Biotin deficiency inhibits heme synthesis and impairs mitochondria in human lung fibroblastsQ79445342
Phase 1 Trial of an RNA Interference Therapy for Acute Intermittent PorphyriaQ91379869
P433issue3
P304page(s)228-235
P577publication date2019-05-20
P1433published inMolecular Genetics and MetabolismQ6895949
P1476titlePilot study of mitochondrial bioenergetics in subjects with acute porphyrias
P478volume128

Reverse relations

Q91209146Porphyria-induced posterior reversible encephalopathy syndrome and central nervous system dysfunctioncites workP2860