Pancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway

scientific article published on 04 June 2019

Pancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1177/0963689719851772
P932PMC publication ID6767883
P698PubMed publication ID31161784

P50authorLigang NanQ87301492
Tao QinQ90149207
P2093author name stringZheng Wang
Jie Li
Ying Xiao
Zheng Wu
Qingyong Ma
Jiguang Ma
Weikun Qian
P2860cites workSonic hedgehog paracrine signaling activates stromal cells to promote perineural invasion in pancreatic cancerQ53040486
Pancreatic CancerQ54135367
Perineural invasion in pancreatic cancer: proteomic analysis and in vitro modellingQ64064095
Clinicopathological study on neural invasion to the extrapancreatic nerve plexus in pancreatic cancerQ67845622
Expression of the Met/hepatocyte growth factor receptor in human pancreatic cancerQ72571222
Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancerQ73181692
Hepatocyte growth-factor and its receptor C-met regulate both cell-growth and invasion of human pancreatic-cancerQ84066341
L1CAM induces perineural invasion of pancreas cancer cells by upregulation of metalloproteinase expressionQ91254655
Targeting the Hepatocyte Growth Factor–cMET Axis in Cancer TherapyQ24606259
Hypoxia promotes invasive growth by transcriptional activation of the met protooncogeneQ28202069
Met, metastasis, motility and moreQ28235183
Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathwayQ28305550
Matrix Metalloproteinase Inhibitors and Cancer--Trials and TribulationsQ29544430
Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves.Q30433458
Clinical significance of carcinoma invasion of the extrapancreatic nerve plexus in pancreatic cancerQ34734177
Met receptor signaling is required for sensory nerve development and HGF promotes axonal growth and survival of sensory neurons.Q35199939
Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreatic cancerQ35741542
SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathwayQ36126649
Hepatocyte growth factor inhibition: a novel therapeutic approach in pancreatic cancerQ36547939
Prenatal Expression of MET Receptor Tyrosine Kinase in the Fetal Mouse Dorsal Raphe Nuclei and the Visceral Motor/Sensory BrainstemQ37101439
Perineural invasion and associated pain in pancreatic cancerQ37937421
Role of glial cell line-derived neurotrophic factor in perineural invasion of pancreatic cancerQ38002666
Inhibition of transforming growth factor-β signaling potentiates tumor cell invasion into collagen matrix induced by fibroblast-derived hepatocyte growth factor.Q39000276
Cancer cell‐derived IL‐1α promotes HGF secretion by stromal cells and enhances metastatic potential in pancreatic cancer cellsQ39651237
Neural invasion in pancreatic cancer: a mutual tropism between neurons and cancer cellsQ39959402
Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1.Q40059254
Regulatory role of c-Met in insulin-like growth factor-I receptor-mediated migration and invasion of human pancreatic carcinoma cellsQ40246790
Establishment of perineural invasion models and analysis of gene expression revealed an invariant chain (CD74) as a possible molecule involved in perineural invasion in pancreatic cancerQ40287695
In vitro dorsal root ganglia and human prostate cell line interaction: Redefining perineural invasion in prostate cancerQ40762956
Scatter factor is a fibroblast-derived modulator of epithelial cell mobilityQ42807925
Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neuronsQ43819365
HGF regulates VEGF expression via the c-Met receptor downstream pathways, PI3K/Akt, MAPK and STAT3, in CT26 murine cellsQ43876212
Coexpression of the c-met proto-oncogene and hepatocyte growth factor in human pancreatic cancerQ46602989
Cancer statistics, 2018.Q47191906
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P6216copyright statuscopyrightedQ50423863
P433issue9-10
P921main subjectpancreatic cancerQ212961
invasion facilitationQ112111173
P304page(s)1289-1298
P577publication date2019-06-04
P1433published inCell TransplantationQ15761863
P1476titlePancreatic Stellate Cells Facilitate Perineural Invasion of Pancreatic Cancer via HGF/c-Met Pathway
P478volume28

Reverse relations

Q92541764Ping-Pong-Tumor and Host in Pancreatic Cancer Progressioncites workP2860

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