A Chinese Herbal Formulation, Xiao-Er-An-Shen Decoction, Attenuates Tourette Syndrome, Possibly by Reversing Abnormal Changes in Neurotransmitter Levels and Enhancing Antioxidant Status in Mouse Brain

scientific article published on 24 July 2019

A Chinese Herbal Formulation, Xiao-Er-An-Shen Decoction, Attenuates Tourette Syndrome, Possibly by Reversing Abnormal Changes in Neurotransmitter Levels and Enhancing Antioxidant Status in Mouse Brain is …
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scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2019.00812
P932PMC publication ID6667554
P698PubMed publication ID31396086

P50authorHoi Yan LeungQ92395678
P2093author name stringJianping Chen
Jihang Chen
Kam Ming Ko
Pou Kuan Leong
Wing Man Chan
Zhonggui Li
Jingyu Qiu
P2860cites workA Single Case of Tourette's Syndrome Treated with Traditional Chinese MedicineQ47230938
Long-term dietary supplementation with a yang-invigorating Chinese herbal formula increases lifespan and mitigates age-associated declines in mitochondrial antioxidant status and functional ability of various tissues in male and female C57BL/6J miceQ47397809
GABA and glutamate in children with Tourette syndrome: A 1H MR spectroscopy study at 7T.Q47867187
Mechanism of neurotoxic action of beta,beta'-iminodipropionitrile (IDPN): N-hydroxylation enhances neurotoxic potencyQ48170205
Brain monoamines and amino acids in Gilles de la Tourette's syndrome: a preliminary study of subcortical regionsQ48464011
"Hyperglutamatergic cortico-striato-thalamo-cortical circuit" breaker drugs alleviate tics in a transgenic circuit model of Tourette׳s syndrome.Q52148177
A Chinese Herbal Preparation, Xiao-Er-An-Shen Decoction, Exerts Neuron Protection by Modulation of Differentiation and Antioxidant Activity in Cultured PC12 Cells.Q54977492
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Obsessive-Compulsive Disorder and Tourette's SyndromeQ73239094
Addressing the Complexity of Tourette's Syndrome through the Use of Animal ModelsQ26752605
Genetic susceptibility and neurotransmitters in Tourette syndromeQ27008846
Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndromeQ33758561
Increased GABA contributes to enhanced control over motor excitability in Tourette syndromeQ34042170
Early administration of tiapride to young rats without long-lasting changes in the development of the dopaminergic systemQ34551682
Synaptic mitochondria in synaptic transmission and organization of vesicle pools in health and diseaseQ34689753
Immunopathogenic mechanisms in tourette syndrome: A critical reviewQ34974740
Dual ameliorative effects of Ningdong granule on dopamine in rat models of Tourette's syndromeQ34975245
γ-Glutamylcysteine detoxifies reactive oxygen species by acting as glutathione peroxidase-1 cofactorQ35863718
Widespread abnormality of the γ-aminobutyric acid-ergic system in Tourette syndromeQ35986696
Obsessive-compulsive disorder in Tourette's syndrome.Q36356102
Chinese Medicine Formula "Jian-Pi-Zhi-Dong Decoction" Attenuates Tourette Syndrome via Downregulating the Expression of Dopamine Transporter in MiceQ36616177
Ursolic-Acid-Enriched Herba Cynomorii Extract Protects against Oxidant Injury in H9c2 Cells and Rat Myocardium by Increasing Mitochondrial ATP Generation Capacity and Enhancing Cellular Glutathione Redox Cycling, Possibly through Mitochondrial UncouQ36801928
Dopaminergic drug effects on physiological connectivity in a human cortico-striato-thalamic system.Q37338740
Globus Pallidus Interna in Tourette Syndrome: Decreased Local Activity and Disrupted Functional Connectivity.Q37340346
Involvement of immunologic and biochemical mechanisms in the pathogenesis of Tourette's syndromeQ37607298
Effect of "jian-pi-zhi-dong decoction" on gamma-aminobutyric Acid in a mouse model of tourette syndrome.Q37724959
Antioxidant efficacy and the upregulation of Nrf2-mediated HO-1 expression by (+)-lariciresinol, a lignan isolated from Rubia philippinensis, through the activation of p38.Q37737833
Treatment strategies for tics in Tourette syndromeQ37845661
Oxidative stress and antioxidant defenseQ38069883
(-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cellsQ42750294
Behavioural study of the D-galactose induced aging model in C57BL/6J miceQ45216218
The novel antioxidant edaravone: from bench to bedsideQ46591722
Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway.Q46695886
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectTourette syndromeQ191779
P304page(s)812
P577publication date2019-07-24
P1433published inFrontiers in PharmacologyQ2681208
P1476titleA Chinese Herbal Formulation, Xiao-Er-An-Shen Decoction, Attenuates Tourette Syndrome, Possibly by Reversing Abnormal Changes in Neurotransmitter Levels and Enhancing Antioxidant Status in Mouse Brain
P478volume10

Reverse relations

Q99238110Current Status, Diagnosis, and Treatment Recommendation for Tic Disorders in Chinacites workP2860