Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env

scientific article published on 15 May 2019

Antibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.00293-19
P932PMC publication ID6532100
P698PubMed publication ID30894474

P50authorAndrés FinziQ60727346
Jérémie PrévostQ112055686
Halima MedjahedQ114512878
P2093author name stringDavid T Evans
Walther Mothes
Marzena Pazgier
Jonathan Richard
Shilei Ding
William D Tolbert
Sai Priya Anand
Jonathan R Grover
Sophie Baril
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The SH3 domain of amphiphysin binds the proline-rich domain of dynamin at a single site that defines a new SH3 binding consensus sequenceQ28238018
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CD4 occupancy triggers sequential pre-fusion conformational states of the HIV-1 envelope trimer with relevance for broadly neutralizing antibody activityQ61815651
HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progressionQ71396764
Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected CellsQ93079833
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A tyrosine-based motif in the HIV-1 envelope glycoprotein tail mediates cell-type- and Rab11-FIP1C-dependent incorporation into virionsQ35764347
Residues in the hendra virus fusion protein transmembrane domain are critical for endocytic recyclingQ35826217
Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant VirusesQ36053810
Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated CytotoxicityQ36086204
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Nef Proteins from HIV-1 Elite Controllers Are Inefficient at Preventing Antibody-Dependent Cellular CytotoxicityQ36736588
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Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope GlycoproteinsQ37363561
Release of gp120 Restraints Leads to an Entry-Competent Intermediate State of the HIV-1 Envelope GlycoproteinsQ37366342
Interaction with cellular CD4 exposes HIV-1 envelope epitopes targeted by antibody-dependent cell-mediated cytotoxicityQ37644079
Role of HIV-1 Envelope Glycoproteins Conformation and Accessory Proteins on ADCC Responses.Q38574538
Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In VivoQ38652858
Impaired Downregulation of NKG2D Ligands by Nef Proteins from Elite Controllers Sensitizes HIV-1-Infected Cells to Antibody-Dependent Cellular Cytotoxicity.Q38725490
NKG2D Acts as a Co-receptor for Natural Killer Cell-Mediated Anti-HIV-1 Antibody-Dependent Cellular CytotoxicityQ38754011
Conformational evaluation of HIV-1 trimeric envelope glycoproteins using a cell-based ELISA assay.Q38950236
Broadly neutralizing HIV antibodies define a glycan-dependent epitope on the prefusion conformation of gp41 on cleaved envelope trimersQ39001126
Antibody-Induced Internalization of the Human Respiratory Syncytial Virus Fusion ProteinQ40216566
BST-2 Expression Modulates Small CD4-Mimetic Sensitization of HIV-1-Infected Cells to Antibody-Dependent Cellular CytotoxicityQ40279352
Feline infectious peritonitis virus-infected monocytes internalize viral membrane-bound proteins upon antibody additionQ40280886
Endocytosis of the Nipah virus glycoproteinsQ40454342
A Highly Conserved gp120 Inner Domain Residue Modulates Env Conformation and Trimer StabilityQ40664564
A single amino acid change in the cytoplasmic domains of measles virus glycoproteins H and F alters targeting, endocytosis, and cell fusion in polarized Madin-Darby canine kidney cellsQ40804996
A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A AntibodiesQ40882652
Antibody-dependent cellular cytotoxicity independently predicts survival in severely immunocompromised human immunodeficiency virus-infected patientsQ41689302
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Antibody-induced internalization of viral glycoproteins and gE-gI Fc receptor activity protect pseudorabies virus-infected monocytes from efficient complement-mediated lysisQ43530697
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Envelope glycoproteins sampling states 2/3 are susceptible to ADCC by sera from HIV-1-infected individualsQ47564695
Impact of HIV-1 Envelope Conformation on ADCC Responses.Q47574397
A membrane-proximal tyrosine-based signal mediates internalization of the HIV-1 envelope glycoprotein via interaction with the AP-2 clathrin adaptorQ47981910
Absence of viral antigens on the surface of equine herpesvirus-1-infected peripheral blood mononuclear cells: a strategy to avoid complement-mediated lysisQ49035095
HIV-1 Env trimer opens through an asymmetric intermediate in which individual protomers adopt distinct conformations.Q52645335
Incomplete Downregulation of CD4 Expression Affects HIV-1 Env Conformation and Antibody-Dependent Cellular Cytotoxicity Responses.Q54233000
Uninfected Bystander Cells Impact the Measurement of HIV-Specific Antibody-Dependent Cellular Cytotoxicity Responses.Q55411165
Antibody-dependent cellular cytotoxicity in HIV infectionQ59352288
P4510describes a project that usesImageJQ1659584
P433issue11
P577publication date2019-05-15
P1433published inJournal of VirologyQ1251128
P1476titleAntibody-Induced Internalization of HIV-1 Env Proteins Limits Surface Expression of the Closed Conformation of Env
P478volume93

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cites work (P2860)
Q90107838Antibody-mediated complement activation in pathology and protection
Q90705235CAR Talk: How Cancer-Specific CAR T Cells Can Instruct How to Build CAR T Cells to Cure HIV
Q99557057Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail
Q64269048Immune Correlates of Disease Progression in Linked HIV-1 Infection
Q90371166Loss of Nef-mediated CD3 down-regulation in the HIV-1 lineage increases viral infectivity and spread
Q93078490Understudied Factors Influencing Fc-Mediated Immune Responses against Viral Infections

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