Chlorogenic acid isomers directly interact with Keap 1-Nrf2 signaling in Caco-2 cells

scientific article published on 20 March 2019

Chlorogenic acid isomers directly interact with Keap 1-Nrf2 signaling in Caco-2 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1007/S11010-019-03516-9
P932PMC publication ID6548765
P698PubMed publication ID30895499

P50authorDavid D KittsQ92516946
Rickey Y. YadaQ47844204
P2093author name stringNingjian Liang
John H Dupuis
P2860cites workFree radicals and antioxidants in normal physiological functions and human diseaseQ21710698
Effect of chlorogenic acid on hydroxyl radicalQ23917185
Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signalingQ24298930
CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fieldsQ24632987
Role of Chlorogenic Acids in Controlling Oxidative and Inflammatory Stress ConditionsQ26771798
SwissDock, a protein-small molecule docking web service based on EADock DSSQ27144176
Study on the nitric oxide scavenging effects of ginseng and its compounds.Q50738696
Chlorogenic Acid and Its Microbial Metabolites Exert Anti-Proliferative Effects, S-Phase Cell-Cycle Arrest and Apoptosis in Human Colon Cancer Caco-2 Cells.Q52728501
Hydrogen bond formation as basis for radical scavenging activity: a structure-activity study of C-methylated dihydrochalcones from Myrica gale and structurally related acetophenonesQ71869400
Antioxidant activity of polyphenolics in diets. Rate constants of reactions of chlorogenic acid and caffeic acid with reactive species of oxygen and nitrogenQ73456701
2,2'-Azobis (4-methoxy-2,4-dimethylvaleronitrile), a new lipid-soluble azo initiator: application to oxidations of lipids and low-density lipoprotein in solution and in aqueous dispersionsQ74060335
In vitro antioxidant activity of coffee compounds and their metabolitesQ80680468
GROMACS: fast, flexible, and freeQ27860998
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidantsQ28218883
Regulation of cellular signals from nutritional molecules: a specific role for phytochemicals, beyond antioxidant activityQ28292706
Enhancement by catechols of hydroxyl-radical formation in the presence of ferric ions and hydrogen peroxideQ28342626
Assessing the antioxidant activity of melanoidins from coffee brews by different antioxidant methodsQ33224144
Antioxidant activity applying an improved ABTS radical cation decolorization assayQ33865975
The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics.Q34415669
Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)Q34550467
Antioxidant and DNA-protective activities of chlorogenic acid isomersQ34660916
Experimental colitis in mice is attenuated by topical administration of chlorogenic acidQ35626127
Optimization of the additive CHARMM all-atom protein force field targeting improved sampling of the backbone φ, ψ and side-chain χ(1) and χ(2) dihedral anglesQ36546184
Application of Attenuated Total Reflectance-Fourier Transformed Infrared (ATR-FTIR) Spectroscopy To Determine the Chlorogenic Acid Isomer Profile and Antioxidant Capacity of Coffee BeansQ40150222
Biological and chemical assessment of antioxidant activity of sugar-lysine model maillard reaction productsQ40394739
Structure-antioxidant activity relationships of flavonoids and phenolic acidsQ41067074
Automation of the CHARMM General Force Field (CGenFF) I: bond perception and atom typing.Q42199119
Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell linesQ43000048
Inhibition of NO production by activated macrophages by phenolcarboxylic acid monomers and polymers with radical scavenging activityQ44487004
Determining conditions for nitric oxide synthesis in Caco-2 cells using Taguchi and factorial experimental designsQ46457316
Tocopherol isoforms (α-, γ-, and δ-) show distinct capacities to control Nrf-2 and NfκB signaling pathways that modulate inflammatory response in Caco-2 intestinal cellsQ46766470
Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent sulforaphaneQ46854767
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1-2
P921main subjectCaco-2Q5016050
P304page(s)105-118
P577publication date2019-03-20
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleChlorogenic acid isomers directly interact with Keap 1-Nrf2 signaling in Caco-2 cells
P478volume457

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cites work (P2860)
Q92733974Modulation of Antibacterial, Antioxidant, and Anti-Inflammatory Properties by Drying of Prunus domestica L. Plum Juice Extracts
Q91964035Molecular Mechanisms That Define Redox Balance Function in Pathogen-Host Interactions-Is There a Role for Dietary Bioactive Polyphenols?
Q92817653NRF2 as a Therapeutic Target in Neurodegenerative Diseases
Q92372931Viburnum opulus Fruit Phenolic Compounds as Cytoprotective Agents Able to Decrease Free Fatty Acids and Glucose Uptake by Caco-2 Cells

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