The Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair

scientific article published on 17 December 2019

The Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3389/FPHAR.2019.01479
P932PMC publication ID6928593
P698PubMed publication ID31920664

P2093author name stringSilvia Oggero
Lucy Victoria Norling
Shani Austin-Williams
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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequencesQ21147057
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Sickle blood contains tissue factor-positive microparticles derived from endothelial cells and monocytesQ47835134
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The majority of circulating platelet-derived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of glycoprotein Ib.Q50191909
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Platelet extracellular vesicles induce a pro-inflammatory smooth muscle cell phenotype.Q38674677
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Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infectionQ39200565
Microvesicle protein levels are associated with increased risk for future vascular events and mortality in patients with clinically manifest vascular diseaseQ39452734
Prospective study on circulating MicroRNAs and risk of myocardial infarctionQ39583273
Microparticles from apoptotic monocytes enhance nitrosative stress in human endothelial cellsQ39628120
Exosome secretion of dendritic cells is regulated by Hrs, an ESCRT-0 protein.Q39673371
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Platelet microparticles are heterogeneous and highly dependent on the activation mechanism: studies using a new digital flow cytometerQ39781488
Astrocytes and Glioblastoma cells release exosomes carrying mtDNA.Q39812809
Multivesicular endosome biogenesis in the absence of ESCRTsQ39843842
Membrane array-based differential profiling of platelets during storage for 52 miRNAs associated with apoptosisQ39985299
Lymphocytic microparticles inhibit angiogenesis by stimulating oxidative stress and negatively regulating VEGF-induced pathwaysQ40043141
Activation of plasminogen into plasmin at the surface of endothelial microparticles: a mechanism that modulates angiogenic properties of endothelial progenitor cells in vitroQ40112496
Elevated levels of VE-cadherin-positive endothelial microparticles in patients with type 2 diabetes mellitus and coronary artery diseaseQ40422877
Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endotheliumQ40423150
Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancerQ40500955
Activated platelet and oxidized LDL induce endothelial membrane vesiculation: clinical significance of endothelial cell-derived microparticles in patients with type 2 diabetesQ40536806
Endothelial and platelet microparticles in vasculitis of the young.Q40538261
Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosisQ40646486
Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-κB in endothelial cellsQ40659069
Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activityQ40732139
Platelets in diabetes: the role in the hemostatic regulation in atherosclerosisQ40837696
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant.Q40851071
Arachidonic acid in platelet microparticles up-regulates cyclooxygenase-2-dependent prostaglandin formation via a protein kinase C/mitogen-activated protein kinase-dependent pathwayQ40969063
Immune activated monocyte exosomes alter microRNAs in brain endothelial cells and initiate an inflammatory response through the TLR4/MyD88 pathwayQ41564855
SNAREs and NSF in targeted membrane fusionQ41566661
Platelet-derived interleukin 1 induces human endothelial adhesion molecule expression and cytokine productionQ41851230
Sonic hedgehog-modified human CD34+ cells preserve cardiac function after acute myocardial infarctionQ41954783
Microvesicle release is associated with extensive protein tyrosine dephosphorylation in platelets stimulated by A23187 or a mixture of thrombin and collagenQ41975625
Autocrine activation of human monocyte/macrophages by monocyte-derived microparticles and modulation by PPARγ ligandsQ42008613
Extravasating Neutrophil-derived Microparticles Preserve Vascular Barrier Function in Inflamed TissueQ42080820
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Atherosclerosis, platelets and thrombosis in acute ischaemic heart diseaseQ42581726
Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression.Q42773654
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Platelet activation in essential hypertension: implications for antiplatelet treatmentQ43186392
MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways.Q43645305
Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactionsQ43852813
Characterisation and properties of ectosomes released by human polymorphonuclear neutrophilsQ44410424
Circulating microparticles from patients with septic shock exert protective role in vascular function.Q44423777
Platelet microparticles induce angiogenesis in vitroQ44724662
Outcomes after acute ischemic stroke in patients with thrombocytopenia or thrombocytosisQ33430508
Monocyte derived microvesicles deliver a cell death message via encapsulated caspase-1.Q33506630
Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.Q33941102
Existence of a microRNA pathway in anucleate plateletsQ34025954
A good practice guide to the administration of substances and removal of blood, including routes and volumesQ34141695
Membrane vesicle release in bacteria, eukaryotes, and archaea: a conserved yet underappreciated aspect of microbial lifeQ34260635
Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediatorsQ34294883
HDL-transferred microRNA-223 regulates ICAM-1 expression in endothelial cellsQ34307544
Inducible microRNA-223 down-regulation promotes TLR-triggered IL-6 and IL-1β production in macrophages by targeting STAT3.Q34398929
Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft modelQ34406142
Strategies to deliver microRNAs as potential therapeutics in the treatment of cardiovascular pathology.Q34485522
Up-regulation of microRNA-155 in macrophages contributes to increased tumor necrosis factor {alpha} (TNF{alpha}) production via increased mRNA half-life in alcoholic liver diseaseQ34489050
Endometrial exosomes/microvesicles in the uterine microenvironment: a new paradigm for embryo-endometrial cross talk at implantationQ34629669
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammationQ34660102
Sonic hedgehog carried by microparticles corrects angiotensin II-induced hypertension and endothelial dysfunction in miceQ34974125
Monocyte exosomes stimulate the osteogenic gene expression of mesenchymal stem cellsQ34995017
Lipopolysaccharide signaling without a nucleus: kinase cascades stimulate platelet shedding of proinflammatory IL-1β-rich microparticlesQ35001472
Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signalingQ35005587
Inflammation-induced endothelial cell-derived extracellular vesicles modulate the cellular status of pericytesQ35089453
MicroRNA expression in circulating microvesicles predicts cardiovascular events in patients with coronary artery diseaseQ35114995
Microparticles in hemostasis and thrombosis.Q35131040
Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healingQ35132356
Monocytic microparticles activate endothelial cells in an IL-1β-dependent mannerQ35182740
Biological properties of extracellular vesicles and their physiological functions.Q35611763
Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAsQ35634914
Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticlesQ35720825
Exosomes/microvesicles from induced pluripotent stem cells deliver cardioprotective miRNAs and prevent cardiomyocyte apoptosis in the ischemic myocardium.Q35748408
Microparticles: major transport vehicles for distinct microRNAs in circulationQ35792749
Platelet microparticles are internalized in neutrophils via the concerted activity of 12-lipoxygenase and secreted phospholipase A2-IIAQ35845952
Mononuclear Phagocyte-Derived Microparticulate Caspase-1 Induces Pulmonary Vascular Endothelial Cell InjuryQ35879582
Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial SepsisQ36035220
Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarctionQ36040528
Endothelial microparticles reduce ICAM-1 expression in a microRNA-222-dependent mechanismQ36057489
Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic ImmunosuppressionQ36067866
Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial MicroparticlesQ61851521
Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell InteractionsQ63408293
Identification of an activated neutrophil phenotype in polymyalgia rheumatica during steroid treatment: a potential involvement of immune cell cross-talkQ64075684
Exosomal Expression of CXCR4 Targets Cardioprotective Vesicles to Myocardial Infarction and Improves Outcome after Systemic AdministrationQ64273125
MHC class II+ exosomes in plasma suppress inflammation in an antigen-specific and Fas ligand/Fas-dependent mannerQ64377029
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritisQ64378678
Platelet-derived microparticles may influence the development of atherosclerosis in diabetes mellitusQ71781373
Protein synthesis by human plateletsQ72215502
Ectosomes released by human neutrophils are specialized functional unitsQ73050613
Induction of relA(p65) and I kappa B alpha subunit expression during differentiation of human peripheral blood monocytes to macrophagesQ73217980
Leukocyte-leukocyte interactions mediated by platelet microparticles under flowQ73426888
Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responsesQ73774768
Expression of functional tissue factor on small vesicles of lipopolysaccharide-stimulated human vascular endothelial cellsQ77408980
Endothelial cell activation by leukocyte microparticlesQ77437049
Effects of severe hypertension on endothelial and platelet microparticlesQ78945402
Circulating leukocyte-derived microparticles predict subclinical atherosclerosis burden in asymptomatic subjectsQ79234231
Monocyte-derived microparticles and exosomes induce procoagulant and apoptotic effects on endothelial cellsQ79804242
Microparticles from apoptotic monocytes induce transient platelet recruitment and tissue factor expression by cultured human vascular endothelial cells via a redox-sensitive mechanismQ81445961
Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticlesQ81561860
Platelet-derived microparticles induce angiogenesis and stimulate post-ischemic revascularizationQ81723006
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Circulating procoagulant microparticles in obesityQ82757597
Endothelial injury and repair in systemic vasculitis of the youngQ83006888
Endothelium-derived microparticles inhibit angiogenesis in the heart and enhance the inhibitory effects of hypercholesterolemia on angiogenesisQ83231659
Number of microparticles generated during acute myocardial infarction and stable angina correlates with platelet activationQ83393028
Human placenta expresses and secretes NKG2D ligands via exosomes that down-modulate the cognate receptor expression: evidence for immunosuppressive functionQ84096693
Circulating level of microparticles and their correlation with arterial elasticity and endothelium-dependent dilation in patients with type 2 diabetes mellitusQ84393427
Involvement of microparticles in diabetic vascular complicationsQ84465761
Exosomes Derived from Immature Bone Marrow Dendritic Cells Induce Tolerogenicity of Intestinal Transplantation in RatsQ85006087
Ectosomes released by platelets induce differentiation of CD4+T cells into T regulatory cellsQ85290797
Angiotensin II induces the generation of procoagulant microparticles by human mononuclear cells via an angiotensin type 2 receptor-mediated pathwayQ86132245
Functionally and morphologically distinct populations of extracellular vesicles produced by human neutrophilic granulocytesQ87330519
Cholesterol and the journey of extracellular vesiclesQ88426782
Exosomal miR-21a-5p mediates cardioprotection by mesenchymal stem cellsQ88483632
Neutrophil-Derived Exosomes: A New Mechanism Contributing to Airway Smooth Muscle RemodelingQ89278867
Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish EmbryoQ91466131
Protein Composition Reflects Extracellular Vesicle HeterogeneityQ91823615
Exosomes derived from monocytes and from endothelial cells mediate monocyte and endothelial cell activation under high d-glucose conditionsQ92084024
Reassessment of Exosome CompositionQ92878002
IL-33 stimulates the release of procoagulant microvesicles from human monocytes and differentially increases tissue factor in human monocyte subsets.Q50656675
Up-Regulated Expression of Matrix Metalloproteinases in Endothelial Cells Mediates Platelet Microvesicle-Induced Angiogenesis.Q50682555
Microparticles during long-term follow-up after acute myocardial infarction. Association to atherosclerotic burden and risk of cardiovascular events.Q50715544
Intercellular transfer of miR-126-3p by endothelial microparticles reduces vascular smooth muscle cell proliferation and limits neointima formation by inhibiting LRP6.Q51159605
Metabolic and Signaling Functions of Cancer Cell-Derived Extracellular Vesicles.Q51544548
Platelet-mediated activation of endothelial cells: implications for the pathogenesis of transplant rejection.Q52543661
Platelet-derived microparticles promote endothelial cell proliferation in hypertension via miR-142-3p.Q52685155
Differential procoagulant activity of microparticles derived from monocytes, granulocytes, platelets and endothelial cells: impact of active tissue factor.Q52785204
Antioxidative treatment inhibits the release of thrombogenic tissue factor from irradiation- and cytokine-induced endothelial cells.Q52927674
Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias.Q53208395
Platelet microparticles reprogram macrophage gene expression and function.Q53358769
Plasma markers of endothelial dysfunction in patients with hypertensive disorders of pregnancy: a pilot study in a South Indian population.Q53363860
Diagnostic role of endothelial microparticles in vasculitis.Q53446731
Circulating endothelial microparticles as a marker of cerebrovascular disease.Q53497260
MicroRNAs in Cardiovascular Disease.Q53641839
Platelet-secreted microRNA-223 promotes endothelial cell apoptosis induced by advanced glycation end products via targeting the insulin-like growth factor 1 receptor.Q53659688
Endothelial cell activation contributes to the release of procoagulant microparticles during acute cardiac allograft rejection.Q53713471
Endothelial microparticle uptake in target cells is annexin I/phosphatidylserine receptor dependent and prevents apoptosis.Q54504167
Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury.Q55057015
Endothelial cells release cardioprotective exosomes that may contribute to ischaemic preconditioningQ58116122
CD3+/CD45+ and SMA-α+ circulating microparticles are increased in individuals at high cardiovascular risk who will develop a major cardiovascular eventQ58419413
Next generation MicroRNA sequencing to identify coronary artery disease patients at risk of recurrent myocardial infarctionQ58584810
Extracellular Vesicles Work as a Functional Inflammatory Mediator Between Vascular Endothelial Cells and Immune CellsQ58798796
LDL extracellular vesicle coagulation protein levels change after initiation of statin therapy. Findings from the METEOR trialQ58824546
Microparticles Produced by Activated Platelets Carry a Potent and Functionally Active Angiogenic Signal in Subjects with Crohn's DiseaseQ59134251
Circulating and platelet-derived microparticles in human blood enhance thrombosis on atherosclerotic plaquesQ60651924
LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7bQ36073902
Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane VesiclesQ36121826
Platelet-derived growth factor and transforming growth factor-beta enhance tissue repair activities by unique mechanismsQ36220355
Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.Q36223338
MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophagesQ36357815
Antibacterial effect of microvesicles released from human neutrophilic granulocytesQ36542831
Comparative proteomic analysis of PAI-1 and TNF-alpha-derived endothelial microparticles.Q36580760
Procoagulant microparticles: disrupting the vascular homeostasis equation?Q36600785
RhoA triggers a specific signaling pathway that generates transforming microvesicles in cancer cells.Q36713922
MicroRNA-146a is a therapeutic target and biomarker for peripartum cardiomyopathyQ36802746
Cross talk of combined gene and cell therapy in ischemic heart disease: role of exosomal microRNA transferQ36888926
The Gas6-Axl Protein Interaction Mediates Endothelial Uptake of Platelet MicroparticlesQ36898211
Cardiac progenitor-derived exosomes protect ischemic myocardium from acute ischemia/reperfusion injury.Q37066520
Heterogeneity in neutrophil microparticles reveals distinct proteome and functional propertiesQ37072869
Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular diseaseQ37073587
Lactadherin and clearance of platelet-derived microvesiclesQ37086945
Microparticle-associated endothelial protein C receptor and the induction of cytoprotective and anti-inflammatory effectsQ37112875
Metastasis suppressor tetraspanin CD82/KAI1 regulates ubiquitylation of epidermal growth factor receptorQ37151134
Effects of ceramide and other simple sphingolipids on membrane lateral structureQ37291700
Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in ratsQ37298327
Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticlesQ37366431
Shedding of vesicular material from the cell surface of eukaryotic cells: different cellular phenomenaQ37545031
Low MT-CO1 in Monocytes and Microvesicles Is Associated With Outcome in Patients With Coronary Artery DiseaseQ37556409
Microvesicle-mediated transfer of microRNA-150 from monocytes to endothelial cells promotes angiogenesisQ37629798
Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion.Q37672715
Clinical relevance of microparticles from platelets and megakaryocytesQ37782534
Platelet- and megakaryocyte-derived microparticlesQ37806997
The many faces of endothelial microparticles.Q37821169
Exosomes: small vesicles participating in intercellular communicationQ37949103
Extracellular vesicles: biology and emerging therapeutic opportunities.Q38098874
Tetraspanins at a glance.Q38240344
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectextracellular vesicleQ21097485
P304page(s)1479
P577publication date2019-12-17
P1433published inFrontiers in PharmacologyQ2681208
P1476titleThe Contrasting Role of Extracellular Vesicles in Vascular Inflammation and Tissue Repair
P478volume10

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