Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity

scientific article published on 13 August 2019

Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41419-019-1857-X
P932PMC publication ID6691115
P698PubMed publication ID31406108

P50authorAnnie TurkiehQ58816440
Florence PinetQ32427967
P2093author name stringPhilippe Amouyel
Jean-Luc Balligand
Maggy Chwastyniak
Olivia Beseme
Nicolas Lamblin
Christophe Bauters
Sina Porouchani
P2860cites workUp-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes.Q40342417
Synthesis and functional analyses of nuclear clusterin, a cell death proteinQ40674770
Stress-induced transcription of the clusterin/apoJ gene.Q42200027
Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarctionQ43190981
Clusterin facilitates in vivo clearance of extracellular misfolded proteinsQ43583442
Clusterin: a protective mediator for ischemic cardiomyocytes?Q46581040
Clusterin protects neurons against intracellular proteotoxicityQ47101840
Involvement of clusterin and the aggresome in abnormal protein deposits in myofibrillar myopathies and inclusion body myositis.Q53269828
Exosomal clusterin, identified in the pericardial fluid, improves myocardial performance following MI through epicardial activation, enhanced arteriogenesis and reduced apoptosis.Q53433900
Rapamycin protects cardiomyocytes against anoxia/reoxygenation injury by inducing autophagy through the PI3k/Akt pathway.Q53611960
Expression and Implication of Clusterin in Left Ventricular Remodeling After Myocardial Infarction.Q54976497
Apolipoprotein E and clusterin inhibit the early phase of amyloid-β aggregation in an in vitro model of cerebral amyloid angiopathyQ61443158
Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction.Q64885580
Transforming growth factor beta (TGF beta)-induced nuclear localization of apolipoprotein J/clusterin in epithelial cellsQ71087317
Co-deposition of clusterin with the complement membrane attack complex in myocardial infarctionQ72660259
Serum levels of the senescence biomarker clusterin/apolipoprotein J increase significantly in diabetes type II and during development of coronary heart disease or at myocardial infarctionQ78624858
The role of autophagy emerging in postinfarction cardiac remodellingQ83619910
The ubiquitin proteasome system and myocardial ischemiaQ28280898
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPSQ28306195
Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte deathQ28579471
Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptideQ29977749
Clusterin facilitates stress-induced lipidation of LC3 and autophagosome biogenesis to enhance cancer cell survivalQ30611108
Proteasomal and lysosomal protein degradation and heart diseaseQ33573707
Autophagic-lysosomal inhibition compromises ubiquitin-proteasome system performance in a p62 dependent manner in cardiomyocytesQ33800568
The ubiquitin proteasome system in human cardiomyopathies and heart failureQ33816688
Clusterin protects H9c2 cardiomyocytes from oxidative stress-induced apoptosis via Akt/GSK-3β signaling pathwayQ34587120
The interplay between autophagy and the ubiquitin-proteasome system in cardiac proteotoxicityQ34778984
Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.Q34919877
Transcriptional and posttranslational regulation of clusterin by the two main cellular proteolytic pathwaysQ34974750
Enhancement of proteasomal function protects against cardiac proteinopathy and ischemia/reperfusion injury in miceQ35187068
Proapoptotic role of nuclear clusterin in brainQ35374719
Proteasome malfunction activates macroautophagy in the heartQ35536300
Genetically induced moderate inhibition of the proteasome in cardiomyocytes exacerbates myocardial ischemia-reperfusion injury in miceQ36184878
Autophagy is impaired in cardiac ischemia-reperfusion injuryQ36235484
Knockdown of clusterin sensitizes pancreatic cancer cells to gemcitabine chemotherapy by ERK1/2 inactivationQ36579884
Protein quality control and degradation in cardiomyocytesQ36952213
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagyQ37012635
Proteasome inhibition during myocardial infarctionQ37595119
Role of ubiquitin-proteasome system (UPS) in left ventricular hypertrophy (LVH).Q38189389
The CLU-files: disentanglement of a mysteryQ38670777
Autophagy during cardiac remodelingQ38672214
Requirement of clusterin expression for prosurvival autophagy in hypoxic kidney tubular epithelial cellsQ38819963
A novel crosstalk between two major protein degradation systems: regulation of proteasomal activity by autophagy.Q39112279
Tumor-derived secretory clusterin induces epithelial-mesenchymal transition and facilitates hepatocellular carcinoma metastasisQ39271816
Proteasome inhibitors activate autophagy as a cytoprotective response in human prostate cancer cellsQ39780649
P433issue8
P304page(s)608
P577publication date2019-08-13
P1433published inCell Death and DiseaseQ2197222
P1476titleIncreased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity
P478volume10

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