review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/CPT.1538 |
P698 | PubMed publication ID | 31173340 |
P50 | author | Wei Jia | Q59677087 |
P2093 | author name string | Zeping Hu | |
Huanhuan Pang | |||
P2860 | cites work | Cancer-associated IDH1 mutations produce 2-hydroxyglutarate | Q24320239 |
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate | Q24605258 | ||
Pharmacogenomics in the clinic | Q26782786 | ||
Defining the metabolome: size, flux, and regulation | Q26865192 | ||
LC-MS-based metabolomics | Q27015012 | ||
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. | Q27852141 | ||
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML | Q63170614 | ||
On getting there from here | Q82714730 | ||
Metabolomic evaluation of the response to endocrine therapy in patients with prostate cancer | Q87332414 | ||
The differential metabolite profiles of acute lymphoblastic leukaemic patients treated with 6-mercaptopurine using untargeted metabolomics approach | Q87384732 | ||
Metabolomics Platform with Capillary Electrophoresis Coupled with High-Resolution Mass Spectrometry for Plasma Analysis | Q89993505 | ||
Inosine Monophosphate Dehydrogenase Dependence in a Subset of Small Cell Lung Cancers | Q90460856 | ||
Metabolomics-based Discovery of Serum Biomarkers to Predict the Side-effects of Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma | Q90784435 | ||
Critical review of reporting of the data analysis step in metabolomics | Q92104710 | ||
Functional interpretation of metabolomics data as a new method for predicting long-term side effects: treatment of atopic dermatitis in infants | Q30876462 | ||
Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients. | Q33687277 | ||
2-Hydroxyglutarate produced by neomorphic IDH mutations suppresses homologous recombination and induces PARP inhibitor sensitivity. | Q33698756 | ||
Globally Optimized Targeted Mass Spectrometry: Reliable Metabolomics Analysis with Broad Coverage | Q33707386 | ||
Combining NMR and LC/MS Using Backward Variable Elimination: Metabolomics Analysis of Colorectal Cancer, Polyps, and Healthy Controls | Q33745104 | ||
Pharmacometabolomics of statin response | Q33746373 | ||
Pharmaco-metabolomics: an emerging "omics" tool for the personalization of anticancer treatments and identification of new valuable therapeutic targets | Q34234941 | ||
Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis. | Q34509661 | ||
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics | Q34555598 | ||
Metabolomics: a global biochemical approach to drug response and disease | Q34734298 | ||
Pharmacometabolomics: implications for clinical pharmacology and systems pharmacology. | Q35032056 | ||
Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts | Q35152158 | ||
Histology-Guided High-Resolution Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging | Q35848629 | ||
Nephron Toxicity Profiling via Untargeted Metabolome Analysis Employing a High Performance Liquid Chromatography-Mass Spectrometry-based Experimental and Computational Pipeline | Q35905359 | ||
Oxidative stress inhibits distant metastasis by human melanoma cells | Q36277720 | ||
The Recent Developments in Sample Preparation for Mass Spectrometry-Based Metabolomics. | Q36410103 | ||
Metabolic Heterogeneity in Human Lung Tumors. | Q36578111 | ||
Metabolic phenotyping for monitoring ovarian cancer patients | Q36708032 | ||
Metabonomics in pharmaceutical R&D. | Q36735003 | ||
2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas | Q36738040 | ||
Oxylipid Profile of Low-Dose Aspirin Exposure: A Pharmacometabolomics Study | Q36835930 | ||
Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia | Q36928342 | ||
Metabolomic Signatures for Drug Response Phenotypes: Pharmacometabolomics Enables Precision Medicine. | Q37078812 | ||
Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China | Q37240701 | ||
Pharmacometabolomics study identifies circulating spermidine and tryptophan as potential biomarkers associated with the complete pathological response to trastuzumab-paclitaxel neoadjuvant therapy in HER-2 positive breast cancer. | Q37457684 | ||
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics | Q37726989 | ||
Personal model-assisted identification of NAD+ and glutathione metabolism as intervention target in NAFLD. | Q37727707 | ||
New opportunities from the cancer metabolome | Q38059633 | ||
Mammalian cell metabolomics: experimental design and sample preparation. | Q38084231 | ||
Metabolomics in diagnosis and biomarker discovery of colorectal cancer | Q38170912 | ||
Sampling and analysis of metabolomes in biological fluids. | Q38221185 | ||
Mass spectrometric based approaches in urine metabolomics and biomarker discovery | Q38424072 | ||
Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential | Q38740919 | ||
Metabolomics: A Primer | Q38757603 | ||
Emerging applications of metabolomics in drug discovery and precision medicine | Q38769103 | ||
Metabolomics and Metabolic Diseases: Where Do We Stand? | Q38769689 | ||
Discovery of urine biomarkers for bladder cancer via global metabolomics. | Q38822316 | ||
A targeted metabolomics assay for cardiac metabolism and demonstration using a mouse model of dilated cardiomyopathy | Q38830822 | ||
Analytical pitfalls and challenges in clinical metabolomics. | Q38870813 | ||
A distinct glucose metabolism signature of acute myeloid leukemia with prognostic value. | Q38976994 | ||
Quantitative metabolic flux analysis reveals an unconventional pathway of fatty acid synthesis in cancer cells deficient for the mitochondrial citrate transport protein. | Q39179854 | ||
Metabolomic Analysis of Gastric Cancer Progression within the Correa's Cascade Using Ultraperformance Liquid Chromatography-Mass Spectrometry. | Q39627027 | ||
Endogenous metabolites that are substrates of organic anion transporter's (OATs) predict methotrexate clearance. | Q39745836 | ||
Development and Evaluation of a Parallel Reaction Monitoring Strategy for Large-Scale Targeted Metabolomics Quantification. | Q39899313 | ||
Optimization of large-scale pseudotargeted metabolomics method based on liquid chromatography-mass spectrometry | Q39996925 | ||
Metabolic Phenotypes of Response to Vaccination in Humans | Q40202000 | ||
Protocol for quality control in metabolic profiling of biological fluids by U(H)PLC-MS. | Q40271847 | ||
A Pharmacometabonomic Approach To Predicting Metabolic Phenotypes and Pharmacokinetic Parameters of Atorvastatin in Healthy Volunteers. | Q40689724 | ||
Untargeted metabolomics in doping control: detection of new markers of testosterone misuse by ultrahigh performance liquid chromatography coupled to high-resolution mass spectrometry. | Q40708609 | ||
Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia | Q41530079 | ||
A large-scale, multi-center serum metabolite biomarkers identification study for the early detection of hepatocellular carcinoma. | Q41928187 | ||
Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease | Q43676938 | ||
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations. | Q44846620 | ||
Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response | Q44882815 | ||
Development of a universal metabolome-standard method for long-term LC-MS metabolome profiling and its application for bladder cancer urine-metabolite-biomarker discovery. | Q45901663 | ||
A distinct metabolic signature of human colorectal cancer with prognostic potential | Q46172836 | ||
Metabolomics: beyond biomarkers and towards mechanisms | Q46206242 | ||
Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response | Q46311700 | ||
Application of metabolomics to investigate the antitumor mechanism of flavopiridol in MCF-7 breast cancer cells | Q46544594 | ||
mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. | Q47110074 | ||
Endogenous metabolites-mediated communication between OAT1/OAT3 and OATP1B1 may explain the association between SLCO1B1 SNPs and methotrexate toxicity. | Q47247020 | ||
Brain and blood metabolite signatures of pathology and progression in Alzheimer disease: A targeted metabolomics study. | Q47549112 | ||
Lactate Metabolism in Human Lung Tumors | Q47594603 | ||
Serum and urine metabolomics study reveals a distinct diagnostic model for cancer cachexia | Q47605033 | ||
Identification of ω- or (ω-1)-Hydroxylated Medium-Chain Acylcarnitines as Novel Urinary Biomarkers for CYP3A Activity. | Q47649551 | ||
Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis | Q47709977 | ||
Target-based metabolomics for the quantitative measurement of 37 pathway metabolites in rat brain and serum using hydrophilic interaction ultra-high-performance liquid chromatography-tandem mass spectrometry | Q47887938 | ||
Poly-pharmacokinetic Study of a Multicomponent Herbal Medicine in Healthy Chinese Volunteers | Q48733265 | ||
Simultaneous imaging of multiple neurotransmitters and neuroactive substances in the brain by desorption electrospray ionization mass spectrometry. | Q48761168 | ||
A non-target urinary and serum metabolomics strategy reveals therapeutical mechanism of Radix Astragali on adjuvant-induced arthritis rats | Q48823052 | ||
Metabolic biomarker signature to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis. | Q49701167 | ||
An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans. | Q49886777 | ||
Discovery of Potential Biomarkers with Dose- and Time-Dependence in Cisplatin-Induced Nephrotoxicity Using Metabolomics Integrated with a Principal Component-Based Area Calculation Strategy. | Q50865442 | ||
Multiple reaction monitoring-ion pair finder: a systematic approach to transform nontargeted mode to pseudotargeted mode for metabolomics study based on liquid chromatography-mass spectrometry. | Q50987957 | ||
Ascorbate regulates haematopoietic stem cell function and leukaemogenesis. | Q51804038 | ||
The surgical intelligent knife distinguishes normal, borderline and malignant gynaecological tissues using rapid evaporative ionisation mass spectrometry (REIMS). | Q52316523 | ||
Isoform switching as a mechanism of acquired resistance to mutant isocitrate dehydrogenase inhibition | Q57790407 | ||
Acquired resistance to IDH inhibition through trans or cis dimer-interface mutations | Q59085289 | ||
Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome | Q59352321 | ||
Preanalytical Processing and Biobanking Procedures of Biological Samples for Metabolomics Research: A White Paper, Community Perspective (for “Precision Medicine and Pharmacometabolomics Task Group”—The Metabolomics Society Initiative) | Q62032198 | ||
P433 | issue | 3 | |
P921 | main subject | metabolomics | Q12149006 |
P304 | page(s) | 544-556 | |
P577 | publication date | 2019-07-23 | |
P1433 | published in | Clinical Pharmacology & Therapeutics | Q1101529 |
P1476 | title | Emerging Applications of Metabolomics in Clinical Pharmacology | |
P478 | volume | 106 |
Q97415763 | Genetics and Not Shared Environment Explains Familial Resemblance in Adult Metabolomics Data |
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