Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p

scientific article published on 31 July 2019

Gut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2019.01737
P932PMC publication ID6685097
P698PubMed publication ID31417547

P50authorMarc VeldhoenQ38544846
P2093author name stringAnchun Cheng
Florian Lang
Madhuri S Salker
Yogesh Singh
Lisann Pelzl
Shaqiu Zhang
Tamer Al-Maghout
Hang Cao
P2860cites workBiological significance of urolithins, the gut microbial ellagic Acid-derived metabolites: the evidence so farQ21285097
Pomegranate Juice Metabolites, Ellagic Acid and Urolithin A, Synergistically Inhibit Androgen-Independent Prostate Cancer Cell Growth via Distinct Effects on Cell Cycle Control and ApoptosisQ21285102
Dual functions for the endoplasmic reticulum calcium sensors STIM1 and STIM2 in T cell activation and toleranceQ24642248
Ion channels and transporters in lymphocyte function and immunityQ26829714
The Effect of Microbiota and the Immune System on the Development and Organization of the Enteric Nervous SystemQ28072096
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel functionQ28305026
Gut Microbiota Conversion of Dietary Ellagic Acid into Bioactive Phytoceutical Urolithin A Inhibits Heme PeroxidasesQ28552586
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasisQ29616351
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generationQ29620116
Dynamic movement of the calcium sensor STIM1 and the calcium channel Orai1 in activated T-cells: puncta and distal capsQ30482508
Hair loss and defective T- and B-cell function in mice lacking ORAI1Q30483187
Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter speciesQ30829776
Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic.Q33857259
Calcium signaling in immune cells.Q33878792
Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.Q34055973
Regulation of microRNAs by natural agents: new strategies in cancer therapiesQ34194495
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodentsQ34533772
Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism.Q34992930
Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic CellsQ35864608
Sphingomyelin, ORAI1 channels, and cellular Ca2+ signalingQ36013460
Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T CellsQ36126644
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetesQ36323689
MicroRNA-15b/16 Enhances the Induction of Regulatory T Cells by Regulating the Expression of Rictor and mTORQ36351026
TGF-β and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cellsQ36404684
Agonist-selected T cell development requires strong T cell receptor signaling and store-operated calcium entry.Q36892161
microRNAs and the immune responseQ37178538
MicroRNA in the immune system, microRNA as an immune systemQ37524231
Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivoQ37585149
Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the LiteratureQ37700559
Orai1, STIM1, and their associating partnersQ38010152
Regulation of lymphocyte function by ORAI and STIM proteins in infection and autoimmunity.Q38012103
Immuno-miRs: critical regulators of T-cell development, function and ageingQ38237119
The functional contribution of calcium ion flux heterogeneity in T cellsQ38396331
Cross-regulation between cytokine and microRNA pathways in T cells.Q38416948
Urolithin A causes p21 up-regulation in prostate cancer cells.Q38876524
In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cellsQ38882561
Ellagitannins, gallotannins and their metabolites- the contribution to the anti-inflammatory effect of food products and medicinal plantsQ38961188
Biochemical and functional characterization of Orai proteinsQ40172328
Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β-Glucuronidases in Their DispositionQ40298757
Alkaline Cytosolic pH and High Sodium Hydrogen Exchanger 1 (NHE1) Activity in Th9 Cells.Q40540223
Inflammatory bactericidal lectin RegIIIβ: Friend or Foe for the host?Q41990376
T-cell-specific deletion of STIM1 and STIM2 protects mice from EAE by impairing the effector functions of Th1 and Th17 cellsQ41993810
Mycobacterium tuberculosis controls microRNA-99b (miR-99b) expression in infected murine dendritic cells to modulate host immunityQ42225424
Epigallocatechin-3-gallate (EGCG) up-regulates miR-15b expression thus attenuating store operated calcium entry (SOCE) into murine CD4+ T cells and human leukaemic T cell lymphoblastsQ45389799
Nutrients Mediate Intestinal Bacteria-Mucosal Immune CrosstalkQ49266766
Infection with enteric pathogens Salmonella typhimurium and Citrobacter rodentium modulate TGF-beta/Smad Signaling Pathways in the IntestineQ49580133
Safety assessment of Urolithin A, a metabolite produced by the human gut microbiota upon dietary intake of plant derived ellagitannins and ellagic acid.Q50516394
Gut Microbiota in Toxicological Risk Assessment of Drugs and Chemicals: The Need of Hour.Q51149483
MicroRNAs regulate T-cell production of interleukin-9 and identify hypoxia-inducible factor-2α as an important regulator of T helper 9 and regulatory T-cell differentiation.Q51712811
AMPKα1-sensitivity of Orai1 and Ca(2+) entry in T - lymphocytes.Q54406055
Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health StatusQ57759668
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathwayQ60594391
Dietary Polyphenols-Important Non-Nutrients in the Prevention of Chronic Noncommunicable Diseases. A Systematic Review.Q64914298
The role of inflammation in temporal shifts in the inflammatory bowel disease mucosal microbiome.Q64941031
Tissue deconjugation of urolithin A glucuronide to free urolithin A in systemic inflammationQ91662904
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P304page(s)1737
P577publication date2019-07-31
P1433published inFrontiers in ImmunologyQ27723748
P1476titleGut Bacterial Metabolite Urolithin A (UA) Mitigates Ca2+ Entry in T Cells by Regulating miR-10a-5p
P478volume10

Reverse relations

Q97681402Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasiscites workP2860

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