review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Shalaka Mulherkar | Q90062424 |
P2093 | author name string | Kimberley F Tolias | |
P2860 | cites work | Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase | Q22010473 |
Rho‐kinase/ROCK: A key regulator of the cytoskeleton and cell polarity | Q24298069 | ||
Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system | Q24675542 | ||
MAG, myelin and overcoming growth inhibition in the CNS | Q26781653 | ||
Regulation of small GTPases by GEFs, GAPs, and GDIs | Q26825750 | ||
Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration | Q27027490 | ||
The small GTPase RhoA is required for proper locomotor circuit assembly | Q27313141 | ||
Design, synthesis, and biological evaluation of novel, highly active soft ROCK inhibitors | Q27700235 | ||
Rho Kinases in Health and Disease: From Basic Science to Translational Research | Q28080702 | ||
Mechanisms for spatiotemporal regulation of Rho-GTPase signaling at synapses | Q28081571 | ||
Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1 | Q28567180 | ||
A radial glia-specific role of RhoA in double cortex formation | Q28586165 | ||
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho | Q29614250 | ||
Therapeutic Potentials of Synapses after Traumatic Brain Injury: A Comprehensive Review. | Q30356935 | ||
Enhanced neurogenesis in the rodent hippocampus following traumatic brain injury | Q31913133 | ||
H-series protein kinase inhibitors and potential clinical applications | Q33716082 | ||
Fasudil, a Clinically Used ROCK Inhibitor, Stabilizes Rod Photoreceptor Synapses after Retinal Detachment | Q33828265 | ||
Moderate traumatic brain injury causes acute dendritic and synaptic degeneration in the hippocampal dentate gyrus | Q34023694 | ||
The small GTPases RhoA and Rac1 regulate cerebellar development by controlling cell morphogenesis, migration and foliation. | Q34177850 | ||
Role of CRMP-2 in neuronal polarity. | Q34274475 | ||
Combat duty in Iraq and Afghanistan, mental health problems, and barriers to care | Q34330469 | ||
Axon growth inhibition by RhoA/ROCK in the central nervous system | Q34384966 | ||
Regulation of PTEN by Rho small GTPases | Q34406790 | ||
Chronic traumatic encephalopathy in contact sports: a systematic review of all reported pathological cases | Q35074639 | ||
Control of synapse development and plasticity by Rho GTPase regulatory proteins. | Q35084942 | ||
The role of Rho GTPase proteins in CNS neuronal migration | Q35281262 | ||
Actin Out: Regulation of the Synaptic Cytoskeleton | Q36323398 | ||
LIM Kinase, a Newly Identified Regulator of Presynaptic Remodeling by Rod Photoreceptors After Injury | Q36380246 | ||
ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo. | Q36382599 | ||
Applications for ROCK kinase inhibition | Q36649417 | ||
Traumatic Brain Injury Severity Affects Neurogenesis in Adult Mouse Hippocampus | Q36825672 | ||
Changes in the GEF-H1 pathways after traumatic brain injury | Q37089934 | ||
Mild traumatic brain injury results in extensive neuronal degeneration in the cerebral cortex | Q37138928 | ||
RhoA Signaling and Synaptic Damage Occur Within Hours in a Live Pig Model of CNS Injury, Retinal Detachment | Q37152871 | ||
Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation | Q37334531 | ||
Structural dynamics of dendritic spines in memory and cognition | Q37688520 | ||
A postmarketing surveillance study of fasudil treatment after aneurysmal subarachnoid hemorrhage. | Q50690435 | ||
Versican V2 and the central inhibitory domain of Nogo-A inhibit neurite growth via p75NTR/NgR-independent pathways that converge at RhoA. | Q51822782 | ||
ROCK inhibition in models of neurodegeneration and its potential for clinical translation. | Q52604400 | ||
AMA0076, a novel, locally acting Rho kinase inhibitor, potently lowers intraocular pressure in New Zealand white rabbits with minimal hyperemia. | Q54381360 | ||
A phase I/IIa clinical trial of a recombinant Rho protein antagonist in acute spinal cord injury. | Q54606960 | ||
Rho GTPases and their role in organizing the actin cytoskeleton. | Q54612905 | ||
Depression and anxiety across the first 4 years after mild traumatic brain injury: findings from a community-based study | Q58101546 | ||
Impact of Traumatic Brain Injury on Neurogenesis | Q61449890 | ||
ROCK-ALS: Protocol for a Randomized, Placebo-Controlled, Double-Blind Phase IIa Trial of Safety, Tolerability and Efficacy of the Rho Kinase (ROCK) Inhibitor Fasudil in Amyotrophic Lateral Sclerosis | Q64111651 | ||
Effect of AT877 on cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Results of a prospective placebo-controlled double-blind trial | Q68071195 | ||
Lesional expression of RhoA and RhoB following traumatic brain injury in humans | Q80340778 | ||
Old and New Drug Classes Expanding To Include Glaucoma Treatments | Q90906269 | ||
Traumatic Brain Injuries: Pathophysiology and Potential Therapeutic Targets | Q91893765 | ||
MMP-9 Contributes to Dendritic Spine Remodeling Following Traumatic Brain Injury | Q92740963 | ||
Synapse pathology in psychiatric and neurologic disease | Q37738136 | ||
Rho-ROCK inhibition in the treatment of spinal cord injury | Q38072524 | ||
Fasudil and its analogs: a new powerful weapon in the long war against central nervous system disorders? | Q38086608 | ||
Structural plasticity of dendritic spines: the underlying mechanisms and its dysregulation in brain disorders | Q38135177 | ||
The contribution of astrocytes and microglia to traumatic brain injury | Q38263517 | ||
Transcriptomic profiling of astrocytes treated with the Rho kinase inhibitor fasudil reveals cytoskeletal and pro-survival responses | Q38502206 | ||
Rho Kinase (ROCK) Inhibitors and Their Therapeutic Potential | Q38612487 | ||
Regulating Rho GTPases and their regulators | Q38865226 | ||
Pathophysiology Associated with Traumatic Brain Injury: Current Treatments and Potential Novel Therapeutics | Q38887870 | ||
Traumatic Brain Injury-Related Emergency Department Visits, Hospitalizations, and Deaths - United States, 2007 and 2013. | Q38903272 | ||
Cellular functions of the ADF/cofilin family at a glance | Q38922939 | ||
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Rho kinase inhibitor fasudil regulates microglia polarization and function | Q39110739 | ||
RhoA-ROCK Inhibition Reverses Synaptic Remodeling and Motor and Cognitive Deficits Caused by Traumatic Brain Injury. | Q41636767 | ||
Small GTPases Rac and Rho in the maintenance of dendritic spines and branches in hippocampal pyramidal neurons. | Q41745546 | ||
Left-right locomotor circuitry depends on RhoA-driven organization of the neuroepithelium in the developing spinal cord | Q41768091 | ||
Selective death of newborn neurons in hippocampal dentate gyrus following moderate experimental traumatic brain injury | Q41864061 | ||
The small GTPase RhoA is required to maintain spinal cord neuroepithelium organization and the neural stem cell pool. | Q42486077 | ||
Moderate traumatic brain injury triggers rapid necrotic death of immature neurons in the hippocampus | Q42571551 | ||
EphB3 signaling propagates synaptic dysfunction in the traumatic injured brain | Q42597759 | ||
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes | Q42819347 | ||
Fasudil protects hippocampal neurons against hypoxia‐reoxygenation injury by suppressing microglial inflammatory responses in mice | Q42873128 | ||
Fasudil, a Rho kinase inhibitor, drives mobilization of adult neural stem cells after hypoxia/reoxygenation injury in mice | Q43242334 | ||
The Rho-kinase (ROCK) inhibitor Y-27632 protects against excitotoxicity-induced neuronal death in vivo and in vitro | Q43843434 | ||
Traumatic brain injury induced cell proliferation in the adult mammalian central nervous system | Q44091907 | ||
Psychiatric disorders following traumatic brain injury: their nature and frequency | Q44412513 | ||
Understanding sequelae of injury mechanisms and mild traumatic brain injury incurred during the conflicts in Iraq and Afghanistan: persistent postconcussive symptoms and posttraumatic stress disorder | Q44478354 | ||
Involvement of RhoA and possible neuroprotective effect of fasudil, a Rho kinase inhibitor, in NMDA-induced neurotoxicity in the rat retina | Q44985191 | ||
RhoA, RhoB, RhoC, Rac1, Cdc42, and Tc10 mRNA levels in spinal cord, sensory ganglia, and corticospinal tract neurons and long-lasting specific changes following spinal cord injury | Q45286570 | ||
Rho kinase inhibitor Fasudil induces neuroprotection and neurogenesis partially through astrocyte-derived G-CSF. | Q46009054 | ||
Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina | Q46403633 | ||
Effects of fasudil in acute ischemic stroke: results of a prospective placebo-controlled double-blind trial | Q46591653 | ||
Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. | Q46692802 | ||
Activation of Rho after traumatic brain injury and seizure in rats | Q46920789 | ||
Widespread cellular proliferation and focal neurogenesis after traumatic brain injury in the rat. | Q48181722 | ||
Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage | Q48414234 | ||
Rho-kinase inhibitor, fasudil, prevents neuronal apoptosis via the Akt activation and PTEN inactivation in the ischemic penumbra of rat brain | Q48535363 | ||
Efficacy and safety of fasudil in patients with subarachnoid hemorrhage: final results of a randomized trial of fasudil versus nimodipine | Q48821423 | ||
Rho kinase inhibition following traumatic brain injury in mice promotes functional improvement and acute neuron survival but has little effect on neurogenesis, glial responses or neuroinflammation | Q48891777 | ||
Impact of the clinical use of ROCK inhibitor on the pathogenesis and treatment of glaucoma | Q49992681 | ||
Rho Inhibitor VX-210 in Acute Traumatic Subaxial Cervical Spinal Cord Injury: Design of the SPinal Cord Injury Rho INhibition InvestiGation (SPRING) Clinical Trial | Q50115568 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 1 | |
P577 | publication date | 2020-01-18 | |
P1433 | published in | Cells | Q27724621 |
P1476 | title | RhoA-ROCK Signaling as a Therapeutic Target in Traumatic Brain Injury | |
P478 | volume | 9 |
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