TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses

scientific article published on 22 January 2020

TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1038/S41418-020-0495-2
P932PMC publication ID7206068
P698PubMed publication ID31969691

P50authorGian Maria FimiaQ30111944
Manuela AntonioliQ56421728
P2093author name stringAlessandra Romagnoli
Mauro Piacentini
Martina Di Rienzo
P2860cites workA Diversity of Selective Autophagy Receptors Determines the Specificity of the Autophagy PathwayQ90489919
Autophagosome maturation: An epic journey from the ER to lysosomesQ90711161
Regulation of PKCβ levels and autophagy by PML is essential for high-glucose-dependent mesenchymal stem cell adipogenesisQ90787682
Selective Autophagy Receptors in Neuronal Health and DiseaseQ90953740
ER-phagy and human diseasesQ90975570
No Parkin Zone: Mitophagy without ParkinQ90986583
Biological Functions of Autophagy Genes: A Disease PerspectiveQ91003224
Nucleophagy: from homeostasis to diseaseQ91063256
TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1Q91104270
TRIM proteinsQ91161114
TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1Q91549318
Diverse Cellular Roles of AutophagyQ91706547
Selective Autophagy: ATG8 Family Proteins, LIR Motifs and Cargo ReceptorsQ91924629
Restriction of HIV-1 and other retroviruses by TRIM5Q91937602
Transcriptional Regulation of Autophagy: Mechanisms and DiseasesQ91942557
cGAS in action: Expanding roles in immunity and inflammationQ92207115
DNA sensing by the cGAS-STING pathway in health and diseaseQ92267263
Knockdown of TRIM65 inhibits autophagy and cisplatin resistance in A549/DDP cells by regulating miR-138-5p/ATG7Q92501817
Cell death-mediated cytokine release and its therapeutic implicationsQ92665944
Disassembly of the TRIM23-TBK1 Complex by the Us11 Protein of Herpes Simplex Virus 1 Impairs AutophagyQ92689644
The Pyrin Inflammasome in Health and DiseaseQ92921941
A TRIM32-AMBRA1-ULK1 complex initiates the autophagy response in atrophic muscle cellsQ92992251
The tripartite motif family identifies cell compartmentsQ24291183
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognitionQ24302068
The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomesQ24305372
Autophagosomes form at ER-mitochondria contact sitesQ24322618
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunityQ24338801
TRIM family proteins and their emerging roles in innate immunityQ24607229
Expanding the ubiquitin code through post-translational modificationQ26798369
Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusionQ27933991
Autophagy in infection, inflammation, and immunityQ29248363
Autophagy: renovation of cells and tissuesQ29547206
The role of Atg proteins in autophagosome formationQ29547418
WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.Q30090184
Downregulation of active IKK beta by Ro52-mediated autophagyQ30495937
Atg9 vesicles are an important membrane source during early steps of autophagosome formationQ30523963
A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fishQ33406010
Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfishQ33971228
The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagyQ34191643
Signals from the lysosome: a control centre for cellular clearance and energy metabolismQ34340780
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartmentQ34450023
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.Q34728044
Role of autophagy, SQSTM1, SH3GLB1, and TRIM63 in the turnover of nicotinic acetylcholine receptorsQ35319775
Identification of a genomic reservoir for new TRIM genes in primate genomesQ35586967
Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates.Q35676481
Beclin orthologs: integrative hubs of cell signaling, membrane trafficking, and physiologyQ36011788
Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagyQ36799136
A KRAB/KAP1-miRNA cascade regulates erythropoiesis through stage-specific control of mitophagy.Q36917344
Molecular basis of NF-κB signalingQ36918115
PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer DevelopmentQ37232230
ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease modelsQ37491265
'Hints' in the killer protein gasdermin D: unveiling the secrets of gasdermins driving cell deathQ37741018
Limb-girdle muscular dystrophy 2H and the role of TRIM32.Q37865700
TRIM family: Pleiotropy and diversification through homomultimer and heteromultimer formationQ37963307
TRIM21 and the Function of Antibodies inside Cells.Q52759082
Autophagy and Inflammation.Q52781227
Cul3-KLHL20 Ubiquitin Ligase Governs the Turnover of ULK1 and VPS34 Complexes to Control Autophagy Termination.Q55033836
Promyelocytic Leukemia Restricts Enterovirus 71 Replication by Inhibiting Autophagy.Q55266935
Mechanism and medical implications of mammalian autophagyQ57269850
Pyroptosis versus necroptosis: similarities, differences, and crosstalkQ57809696
TRIM16 controls assembly and degradation of protein aggregates by modulating the p62-NRF2 axis and autophagyQ58704576
TRIM Proteins and Their Roles in Antiviral Host DefensesQ59358033
TRIMming down to TRIM37: Relevance to Inflammation, Cardiovascular Disorders, and Cancer in MULIBREY NanismQ60934941
Autophagy induction in atrophic muscle cells requires ULK1 activation by TRIM32 through unanchored K63-linked polyubiquitin chainsQ64062851
Emerging Roles of the TRIM E3 Ubiquitin Ligases MID1 and MID2 in CytokinesisQ64075713
Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17.Q64925280
PML nuclear bodies: from architecture to functionQ88557822
TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axisQ89237323
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellitesQ90100693
TRIM22 regulates macrophage autophagy and enhances Mycobacterium tuberculosis clearance by targeting the nuclear factor-multiplicity κB/beclin 1 pathwayQ90240160
Post-translational modifications of Beclin 1 provide multiple strategies for autophagy regulationQ90463782
Genomics and evolution of the TRIM gene familyQ38103003
Ubiquitin-Dependent And Independent Signals In Selective AutophagyQ38599451
TRIM-NHL proteins in development and diseaseQ38619600
Dedicated SNAREs and specialized TRIM cargo receptors mediate secretory autophagyQ38727042
Receptor usage dictates HIV-1 restriction by human TRIM5α in dendritic cell subsetsQ38727566
Molecular definitions of autophagy and related processes.Q38735356
ER-plasma membrane contact sites contribute to autophagosome biogenesis by regulation of local PI3P synthesisQ38760703
The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.Q38780596
Digesting the Expanding Mechanisms of AutophagyQ38799613
Inflammasomes: mechanism of assembly, regulation and signallingQ38862650
Transcriptional regulation of mammalian autophagy at a glanceQ38928492
Innate immune sensing of bacterial modifications of Rho GTPases by the Pyrin inflammasomeQ38985852
Emerging Mechanisms in Initiating and Terminating Autophagy.Q38986562
TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis.Q39101488
Structural determinants of TRIM protein functionQ39137370
The E3-ligase TRIM family of proteins regulates signaling pathways triggered by innate immune pattern-recognition receptorsQ39188991
Cyclic GMP-AMP as an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA.Q39235226
Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.Q39312592
The non-canonical NF-κB pathway in immunity and inflammationQ39350735
Autophagy contributes to therapy-induced degradation of the PML/RARA oncoproteinQ39688872
Functional interactions between ubiquitin E2 enzymes and TRIM proteins.Q39807649
SnapShot: Selective autophagyQ39879628
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responsesQ40051350
TRIM23 mediates virus-induced autophagy via activation of TBK1.Q40058251
TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses.Q40528170
Sumoylation Promotes the Stability of the DNA Sensor cGAS and the Adaptor STING to Regulate the Kinetics of Response to DNA VirusQ40537677
TRIM11 Suppresses AIM2 Inflammasome by Degrading AIM2 via p62-Dependent Selective AutophagyQ40585385
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradationQ40607133
Fasting-induced hormonal regulation of lysosomal function.Q41070270
The complexity of TRIM28 contribution to cancer.Q41542786
PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infectionQ41603115
AMBRA1 interplay with cullin E3 ubiquitin ligases regulates autophagy dynamicsQ41603230
Enhanced Degradation of Misfolded Proteins Promotes Tumorigenesis.Q41720019
TRIMs and Galectins Globally Cooperate and TRIM16 and Galectin-3 Co-direct Autophagy in Endomembrane Damage HomeostasisQ41863769
Degradation of AMPK by a cancer-specific ubiquitin ligaseQ42276010
Molecular mechanisms of selective autophagyQ42415075
Ubiquitin signaling and autophagyQ47349935
Autophagy balances inflammation in innate immunityQ48255270
Cytosolic lipolysis and lipophagy: two sides of the same coinQ48678334
Cargo recognition and degradation by selective autophagyQ50422083
TRIM50 regulates Beclin 1 proautophagic activity.Q52336048
Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance.Q52375973
Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.Q52587537
Role of autophagy in IL-1β export and release from cells.Q52629816
TANK-Binding Kinase 1-Dependent Responses in Health and Autoimmunity.Q52645929
P433issue3
P921main subjectautophagyQ288322
P304page(s)887-902
P577publication date2020-01-22
P1433published inCell Death & DifferentiationQ2943974
P1476titleTRIM proteins in autophagy: selective sensors in cell damage and innate immune responses
P478volume27

Reverse relations

cites work (P2860)
Q89603095Autophagy participates in, well, just about everything
Q104795144TRIM21-regulated Annexin A2 plasma membrane trafficking facilitates osteosarcoma cell differentiation through the TFEB-mediated autophagy

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