Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms

scientific article published on 19 June 2019

Prognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12885-019-5814-Y
P932PMC publication ID6582551
P698PubMed publication ID31216997

P50authorShu-Xiong ZengQ84230463
P2093author name stringJun Yang
Fei Liu
Chuanliang Xu
Xiaowen Yu
Yinghao Sun
Zhensheng Zhang
Jinshan Xu
Qiao Xiong
Lihe Dai
Anwei Liu
Yongping Xue
P2860cites workTargeting DNA topoisomerase II in cancer chemotherapyQ24649711
Molecular substratification of bladder cancer: moving towards individualized patient managementQ26744343
Comprehensive molecular characterization of urothelial bladder carcinomaQ28306864
PIAS3 expression in squamous cell lung cancer is low and predicts overall survivalQ30405870
Transcriptome sequencing identifies ANLN as a promising prognostic biomarker in bladder urothelial carcinoma.Q33784670
Higher expression of topoisomerase II alpha is an independent marker of increased risk of cancer-specific death in patients with clear cell renal cell carcinomaQ33807370
Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.Q34761951
Predictive value of topoisomerase II alpha immunostaining in urothelial bladder carcinomaQ35398592
Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancerQ35550192
Differential expression in RNA-seq: a matter of depthQ35581592
The association of topoisomerase 2α expression with prognosis in surgically resected non-small cell lung cancer (NSCLC) patientsQ36186309
The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissuesQ36431775
Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells.Q37148274
TOP2A is overexpressed and is a therapeutic target for adrenocortical carcinomaQ37188707
Gene expression alterations in doxorubicin resistant MCF7 breast cancer cell lineQ39234562
Cancer statistics in China, 2015.Q40064386
Updated 2016 EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer.Q40668752
Untangling the role of DNA topoisomerase II in mitotic chromosome structure and function.Q41359103
Expression of topoisomerases II alpha and beta in Chinese hamster lung cells resistant to topoisomerase II inhibitors.Q41449520
Relationship between expression of topoisomerase II isoforms and intrinsic sensitivity to topoisomerase II inhibitors in breast cancer cell linesQ42590977
ERBB2 and TOP2A in breast cancer: a comprehensive analysis of gene amplification, RNA levels, and protein expression and their influence on prognosis and prediction.Q43108071
Clinical implications and prognostic values of topoisomerase-II alpha expression in primary non-muscle-invasive bladder cancerQ44010519
HER-2 and TOP2A coamplification in urinary bladder cancerQ47435490
Nuclear topoisomerase II levels correlate with the sensitivity of mammalian cells to intercalating agents and epipodophyllotoxins.Q54373123
Copy number variation and high expression of DNA topoisomerase II alpha predict worse prognosis of cancer: a meta-analysis.Q55396428
Overexpression of G2 and S phase-expressed-1 contributes to cell proliferation, migration, and invasion via regulating p53/FoxM1/CCNB1 pathway and predicts poor prognosis in bladder cancerQ58581112
Human DNA topoisomerase-IIalpha expression as a prognostic factor for transitional cell carcinoma of the urinary bladderQ73172794
Human DNA topoisomerase II-alpha: a new marker of cell proliferation in invasive breast cancerQ73817989
Topoisomerase IIalpha expression in breast cancer: correlation with outcome variablesQ73821356
P433issue1
P921main subjectbladder urothelial carcinomaQ18556148
P304page(s)604
P577publication date2019-06-19
P1433published inBMC CancerQ326300
P1476titlePrognostic value of TOP2A in bladder urothelial carcinoma and potential molecular mechanisms
P478volume19

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Q92292667An outcome model for human bladder cancer: A comprehensive study based on weighted gene co-expression network analysiscites workP2860

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