Microfluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice

scientific article published on 24 January 2020

Microfluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PONE.0227891
P932PMC publication ID6980563
P698PubMed publication ID31978077

P50authorTaiki AoshiQ92914658
P2093author name stringJie Meng
Ryo Suzuki
Yasunari Haseda
Lisa Munakata
P2860cites workAdjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity.Q30398841
Enantiospecific adjuvant activity of cationic lipid DOTAP in cancer vaccineQ33912706
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Liposomal cationic charge and antigen adsorption are important properties for the efficient deposition of antigen at the injection site and ability of the vaccine to induce a CMI responseQ57955486
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Diffusion of univalent ions across the lamellae of swollen phospholipidsQ59447717
Microfluidic-Based Manufacture of siRNA-Lipid Nanoparticles for Therapeutic ApplicationsQ59900455
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Antigen Priming with Enantiospecific Cationic Lipid Nanoparticles Induces Potent Antitumor CTL Responses through Novel Induction of a Type I IFN ResponseQ91750863
Cancer Vaccines: Steering T Cells Down the Right Path to Eradicate TumorsQ92310063
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Vaccine Adjuvants: Putting Innate Immunity to WorkQ36168232
Microfluidic Synthesis of Highly Potent Limit-size Lipid Nanoparticles for In Vivo Delivery of siRNA.Q36234343
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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profileQ37294444
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Endosomal translocation of vertebrate DNA activates dendritic cells via TLR9-dependent and -independent pathwaysQ38326606
Controllable synthesis of functional nanoparticles by microfluidic platforms for biomedical applications - a review.Q39043037
T cell-dependent antigen adjuvanted with DOTAP-CpG-B but not DOTAP-CpG-A induces robust germinal center responses and high affinity antibodies in miceQ40111632
Mechanism of adjuvant activity of cationic liposome: phosphorylation of a MAP kinase, ERK and induction of chemokinesQ40128844
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon inductionQ40437839
Distribution of adjuvant MF59 and antigen gD2 after intramuscular injection in miceQ41695957
High-throughput manufacturing of size-tuned liposomes by a new microfluidics method using enhanced statistical tools for characterizationQ41748148
Induction of CD8+ T-cell responses against subunit antigens by the novel cationic liposomal CAF09 adjuvantQ42213097
Towards personalized, tumour-specific, therapeutic vaccines for cancer.Q47789519
Features of Effective T Cell-Inducing Vaccines against Chronic Viral InfectionsQ50335281
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P921main subjectnanoparticleQ61231
microfluidicsQ138845
DOTAPQ27284189
P304page(s)e0227891
P577publication date2020-01-24
P1433published inPLOS OneQ564954
P1476titleMicrofluidic-prepared DOTAP nanoparticles induce strong T-cell responses in mice
P478volume15

Reverse relations

Q98291992Comprehensive Screening of Mouse T-Cell Epitopes in Human Herpesvirus 6B Glycoprotein H/L/Q1/Q2 Tetramer Complexcites workP2860

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