scholarly article | Q13442814 |
P356 | DOI | 10.3390/IJMS20174189 |
P953 | full work available online at | https://www.mdpi.com/1422-0067/20/17/4189 |
P932 | PMC publication ID | 6747474 |
P698 | PubMed publication ID | 31461847 |
P2093 | author name string | Yatrik M Shah | |
Daniel Triner | |||
Yatrik M. Shah | |||
P2860 | cites work | Neutrophil infiltration is a favorable prognostic factor in early stages of colon cancer | Q47838906 |
Tumor hypoxia does not drive differentiation of tumor-associated macrophages but rather fine-tunes the M2-like macrophage population. | Q54616861 | ||
Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis | Q57608179 | ||
Hypoxia induces endothelial cells to increase their adherence for neutrophils: role of PAF | Q67567219 | ||
Hypoxia-induced elevation in interleukin-8 expression by human ovarian carcinoma cells | Q73229815 | ||
Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice | Q90503326 | ||
A Positive Feedback Loop Between Cancer Stem-Like Cells and Tumor-Associated Neutrophils Controls Hepatocellular Carcinoma Progression | Q92747215 | ||
Hallmarks of Cancer: The Next Generation | Q22252312 | ||
Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche | Q24606366 | ||
Hypoxia-Inducible Factors in Physiology and Medicine | Q27013770 | ||
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models | Q27727998 | ||
The blockade of immune checkpoints in cancer immunotherapy | Q27860852 | ||
Tumor entrained neutrophils inhibit seeding in the premetastatic lung | Q28247691 | ||
Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth | Q28270711 | ||
Hypoxia upregulates neutrophil degranulation and potential for tissue injury | Q28596234 | ||
HIF-1alpha is essential for myeloid cell-mediated inflammation | Q29617581 | ||
Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TAN | Q29619346 | ||
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation | Q33569771 | ||
Generation of a new therapeutic peptide that depletes myeloid-derived suppressor cells in tumor-bearing mice | Q33721765 | ||
Circulating human peripheral blood granulocytes synthesize and secrete tumor necrosis factor alpha | Q33771233 | ||
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice | Q33927482 | ||
Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation | Q34028645 | ||
Transcriptomic Analysis Comparing Tumor-Associated Neutrophils with Granulocytic Myeloid-Derived Suppressor Cells and Normal Neutrophils | Q34163579 | ||
Macrophages are recruited to hypoxic tumor areas and acquire a pro-angiogenic M2-polarized phenotype via hypoxic cancer cell derived cytokines Oncostatin M and Eotaxin | Q34221784 | ||
Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection | Q34257883 | ||
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid. | Q34429912 | ||
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis | Q34928194 | ||
HIF transcription factors, inflammation, and immunity | Q35137138 | ||
IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis | Q35763387 | ||
MET is required for the recruitment of anti-tumoural neutrophils | Q36125652 | ||
Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis | Q36190681 | ||
TNF signaling drives myeloid-derived suppressor cell accumulation | Q36357903 | ||
Epithelial exposure to hypoxia modulates neutrophil transepithelial migration | Q36367344 | ||
Hypoxia-induced neutrophil survival is mediated by HIF-1alpha-dependent NF-kappaB activity | Q36402484 | ||
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis | Q36404110 | ||
Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells | Q36422289 | ||
Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of beta2 integrin gene expression | Q36672331 | ||
The prognostic landscape of genes and infiltrating immune cells across human cancers | Q36857285 | ||
Neutrophil granulocyte derived MMP-9 is a VEGF independent functional component of the angiogenic switch in pancreatic ductal adenocarcinoma | Q36943936 | ||
Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells | Q37031596 | ||
HIF2α-arginase axis is essential for the development of pulmonary hypertension. | Q37161630 | ||
Endothelial PAS domain protein 1 activates the inflammatory response in the intestinal epithelium to promote colitis in mice | Q37237823 | ||
Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish. | Q37489023 | ||
Neutrophils: key mediators of tumour angiogenesis | Q37534968 | ||
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis | Q37591247 | ||
Prognostic significance of the neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio in patients with stage III and IV colorectal cancer | Q37624508 | ||
Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation | Q37633213 | ||
Targeting renal cell carcinoma with a HIF-2 antagonist. | Q37684974 | ||
Inflammation and colon cancer | Q37737408 | ||
Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment | Q38246724 | ||
Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer. | Q38413010 | ||
Prolyl hydroxylase 2 inactivation enhances glycogen storage and promotes excessive neutrophilic responses | Q38626160 | ||
Pre-metastatic niches: organ-specific homes for metastases. | Q38743711 | ||
Neutrophils in cancer: neutral no more. | Q38860382 | ||
Phenotypic diversity and plasticity in circulating neutrophil subpopulations in cancer. | Q38916509 | ||
Neutrophils recruit regulatory T-cells into tumors via secretion of CCL17--a new mechanism of impaired antitumor immunity | Q39026688 | ||
Tumor-associated neutrophils (TAN) develop pro-tumorigenic properties during tumor progression | Q39087629 | ||
Epithelial Hypoxia-Inducible Factor 2α Facilitates the Progression of Colon Tumors through Recruiting Neutrophils | Q39107166 | ||
Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. | Q39231400 | ||
Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche. | Q39321728 | ||
Inhibition of the Kit ligand/c-Kit axis attenuates metastasis in a mouse model mimicking local breast cancer relapse after radiotherapy. | Q39328708 | ||
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. | Q39507131 | ||
Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway | Q40266970 | ||
Hypoxia-inducible factors: a central link between inflammation and cancer | Q41678975 | ||
Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice | Q41984558 | ||
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer | Q42157682 | ||
HIF-1alpha expression regulates the bactericidal capacity of phagocytes | Q42876119 | ||
Impeding macrophage entry into hypoxic tumor areas by Sema3A/Nrp1 signaling blockade inhibits angiogenesis and restores antitumor immunity. | Q46373208 | ||
Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model | Q46433930 | ||
Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway | Q47159175 | ||
Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma | Q47283034 | ||
P275 | copyright license | Creative Commons Attribution | Q6905323 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 17 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | oxygen | Q629 |
neutrophil | Q188417 | ||
neoplasm | Q1216998 | ||
P304 | page(s) | 4189 | |
P577 | publication date | 2019-01-01 | |
2019-08-27 | |||
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
P1476 | title | Hypoxic Regulation of Neutrophils in Cancer | |
P478 | volume | 20 |
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