Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord

scientific article published on 05 June 2019

Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord is …
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scholarly articleQ13442814

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P356DOI10.3389/FNCEL.2019.00184
P932PMC publication ID6561314
P698PubMed publication ID31231191

P50authorMaría Hidalgo-FigueroaQ85907498
Cédric FranciusQ117771344
P2093author name stringAudrey Harris
Frédéric Clotman
Lynn M Corcoran
Benvenuto Jacob
Gauhar Masgutova
Mathilde Toch
Amandine Collin
P2860cites workOC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6Q22008694
LMO4 controls the balance between excitatory and inhibitory spinal V2 interneuronsQ24310006
A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor poolQ24338675
Decision making during interneuron migration in the developing cerebral cortexQ26998689
Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cordQ27310326
Generation of Pet1210-Cre transgenic mouse line reveals non-serotonergic expression domains of Pet1 both in CNS and peripheryQ27316205
The Onecut transcription factor HNF-6 regulates in motor neurons the formation of the neuromuscular junctionsQ27333963
Molecular and cellular development of spinal cord locomotor circuitryQ28082501
Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survivalQ28513024
Hepatocyte nuclear factor 6, a transcription factor that contains a novel type of homeodomain and a single cut domainQ28565610
Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron developmentQ84623717
Separate microcircuit modules of distinct v2a interneurons and motoneurons control the speed of locomotionQ87577540
Origin and circuitry of spinal locomotor interneurons generating different speedsQ88590644
Mini-Oct and Oct-2c: two novel, functionally diverse murine Oct-2 gene products are differentially expressed in the CNSQ48517170
HNF-6 is expressed in endoderm derivatives and nervous system of the mouse embryo and participates to the cross-regulatory network of liver-enriched transcription factorsQ48556896
Graded Arrays of Spinal and Supraspinal V2a Interneuron Subtypes Underlie Forelimb and Hindlimb Motor ControlQ49342255
Diversity of molecularly defined spinal interneurons engaged in mammalian locomotor pattern generationQ50267128
V3 interneuron subpopulations in the mouse spinal cord undergo distinctive postnatal maturation processes.Q50595115
Sim1 is required for the migration and axonal projections of V3 interneurons in the developing mouse spinal cord.Q50602807
The Onecut transcription factor HNF-6 contributes to proper reorganization of Purkinje cells during postnatal cerebellum development.Q50744632
The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm.Q50792142
Motor antagonism exposed by spatial segregation and timing of neurogenesis.Q51850262
Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2.Q52100380
Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse.Q53204300
Regulated splicing of the Oct-2 transcription factor RNA in neuronal cellsQ72227656
Transcriptional stimulation by hepatocyte nuclear factor-6. Target-specific recruitment of either CREB-binding protein (CBP) or p300/CBP-associated factor (p/CAF)Q73794094
LIM factor Lhx3 contributes to the specification of motor neuron and interneuron identity through cell-type-specific protein-protein interactionsQ74548348
Genetic ablation of V2a ipsilateral interneurons disrupts left-right locomotor coordination in mammalian spinal cordQ79673481
Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factorsQ28585487
All known in vivo functions of the Oct-2 transcription factor require the C-terminal protein domainQ28589066
Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cordQ28589093
Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3Q28591310
OC-3, a novel mammalian member of the ONECUT class of transcription factorsQ28594125
Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cordQ28750357
Genetic dissection of rhythmic motor networks in miceQ34664156
Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor programQ35595477
A genetically defined asymmetry underlies the inhibitory control of flexor-extensor locomotor movementsQ36158633
Regulation of normal B-cell differentiation and malignant B-cell survival by OCT2.Q36802522
A high throughput embryonic stem cell screen identifies Oct-2 as a bifunctional regulator of neuronal differentiationQ37135184
Firing and cellular properties of V2a interneurons in the rodent spinal cordQ37347581
Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cordQ37398499
Functional subpopulations of V3 interneurons in the mature mouse spinal cordQ37488749
Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.Q37531618
Generating spinal motor neuron diversity: a long quest for neuronal identityQ38114332
Identification of CD36 as the first gene dependent on the B-cell differentiation factor Oct-2.Q38293977
Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversificationQ38323216
Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver developmentQ38409109
Assembly and function of spinal circuits for motor controlQ38590906
Tangential migration of glutamatergic neurons and cortical patterning during development: Lessons from Cajal-Retzius cellsQ38637516
Making sense out of spinal cord somatosensory developmentQ38972220
Spinal Inhibitory Interneuron Diversity Delineates Variant Motor MicrocircuitsQ39524728
Patterns of spinal sensory-motor connectivity prescribed by a dorsoventral positional templateQ39806479
Multiple Oct2 isoforms are generated by alternative splicingQ40530633
Satb2 Is Required for the Development of a Spinal Exteroceptive Microcircuit that Modulates Limb PositionQ41015829
The Oct-2 transcription factorQ41224982
Alternative splicing of the Oct-2 transcription factor RNA is differentially regulated in neuronal cells and B cells and results in protein isoforms with opposite effects on the activity of octamer/TAATGARAT-containing promotersQ41589861
A regulatory network to segregate the identity of neuronal subtypesQ41853998
Distinct limb and trunk premotor circuits establish laterality in the spinal cordQ42176123
The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord DevelopmentQ42244139
Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneuronsQ42253746
Structure and expression of the mouse Oct2a and Oct2b, two differentially spliced products of the same geneQ42626119
Dual-mode operation of neuronal networks involved in left-right alternationQ43962240
An epilepsy-related ARX polyalanine expansion modifies glutamatergic neurons excitability and morphology without affecting GABAergic neurons developmentQ44328224
Oct-2 transcription factor binding activity and expression up-regulation in rat cerebral ischaemia is associated with a diminution of neuronal damage in vitro.Q46225287
Origin and Segmental Diversity of Spinal Inhibitory InterneuronsQ47226343
Chx10 Consolidates V2a Interneuron Identity through Two Distinct Gene Repression ModesQ47405027
Delineating the Diversity of Spinal Interneurons in Locomotor Circuits.Q47629859
The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascadeQ47867912
Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleusQ48247532
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P304page(s)184
P577publication date2019-06-05
P1433published inFrontiers in Cellular NeuroscienceQ2131509
P1476titleOnecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord
P478volume13