Mesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche

scientific article published on 26 June 2019

Mesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JSP2.1055
P932PMC publication ID6686825
P698PubMed publication ID31463465

P50authorChristine L Le MaitreQ39409436
P2093author name stringChristopher Sammon
Abbey A Thorpe
Joseph Snuggs
Louise Vickers
P2860cites workThe role of interleukin-1 in the pathogenesis of human intervertebral disc degenerationQ24817050
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The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc.Q37691242
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Ca(2+) signals, NAADP and two-pore channels: role in cellular differentiationQ38202209
Degeneration of the intervertebral disc with new approaches for treating low back pain.Q38271248
Cell-based therapies for intervertebral disc and cartilage regeneration- Current concepts, parallels, and perspectivesQ38814837
Class 3 semaphorins expression and association with innervation and angiogenesis within the degenerate human intervertebral disc.Q38842670
Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degenerationQ38957636
Thermally triggered hydrogel injection into bovine intervertebral disc tissue explants induces differentiation of mesenchymal stem cells and restores mechanical functionQ39158557
Biochemical and structural properties of the cartilage end-plate and its relation to the intervertebral disc.Q39286096
Modified expression of the ADAMTS enzymes and tissue inhibitor of metalloproteinases 3 during human intervertebral disc degenerationQ40006569
The structure and degradation of aggrecan in human intervertebral discQ41854830
Regulation of catabolic gene expression in normal and degenerate human intervertebral disc cells: implications for the pathogenesis of intervertebral disc degenerationQ42163509
Function of sustained released resveratrol on IL-1β-induced hBMSC MMP13 secretion inhibition and chondrogenic differentiation promotion.Q42700206
Hypertrophic differentiation and calcification during intervertebral disc degeneration.Q42932253
Nerves are more abundant than blood vessels in the degenerate human intervertebral disc.Q43101289
Senescence in human intervertebral discsQ43167875
Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage: a requisite for tissue engineering of intervertebral disc.Q45189368
Do intervertebral discs degenerate before they herniate, or after?Q47876773
Relative increase of biglycan and decorin and altered chondroitin sulfate epitopes in the degenerating human intervertebral disc.Q50525024
Thermally triggered injectable hydrogel, which induces mesenchymal stem cell differentiation to nucleus pulposus cells: Potential for regeneration of the intervertebral disc.Q50868237
Human cartilaginous endplate degeneration is induced by calcium and the extracellular calcium-sensing receptor in the intervertebral disc.Q51619876
Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes.Q52837664
Physical manipulation of calcium oscillations facilitates osteodifferentiation of human mesenchymal stem cells.Q54559250
Matrix Metalloproteinases And AggrecanaseQ57539949
Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degenerationQ59683291
Micro-CT quantification of subchondral endplate changes in intervertebral disc degenerationQ60977156
Investigation of the role of IL-1 and TNF in matrix degradation in the intervertebral discQ61699189
Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral discQ61699199
Nerve growth factor expression and innervation of the painful intervertebral discQ61699202
Analysis of Tissue Distribution of TNF- , TNF- -Receptors, and the Activating TNF- -Converting Enzyme Suggests Activation of the TNF- System in the Aging Intervertebral DiscQ63341133
Loads on the lumbar spine. Validation of a biomechanical analysis by measurements of intradiscal pressures and myoelectric signalsQ70373595
Low back pain in relation to lumbar disc degenerationQ73522106
Nerve ingrowth into diseased intervertebral disc in chronic back painQ73570649
Mechanical initiation of intervertebral disc degenerationQ73931607
Changes in mRNA and protein levels of proteoglycans of the anulus fibrosus and nucleus pulposus during intervertebral disc degenerationQ78413360
Differential regulation of matrix degrading enzymes in a TNFalpha-induced model of nucleus pulposus tissue degenerationQ80171418
3D spheroid culture system on micropatterned substrates for improved differentiation efficiency of multipotent mesenchymal stem cellsQ83346462
P4510describes a project that usesImageJQ1659584
P433issue2
P921main subjectmesenchymal stem cellQ1922379
P304page(s)e1055
P577publication date2019-06-26
P1433published inJOR SpineQ73541371
P1476titleMesenchymal stem cell therapies for intervertebral disc degeneration: Consideration of the degenerate niche
P478volume2

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Q91601348Wnt3a and wnt5a as Potential Chondrogenic Stimulators for Nucleus Pulposus Cell Induction: A Comprehensive Reviewcites workP2860

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