Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes

scientific article published on 14 May 2019

Variants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/JDI.13057
P932PMC publication ID6825945
P698PubMed publication ID30970177

P50authorHiroshi OnumaQ91908818
Daisuke ChujoQ90298289
Eiji KawasakiQ90350427
P2093author name stringKenji Takahashi
Haruhiko Osawa
Jun Ohashi
Ryoichi Kawamura
Yasunori Takata
Akihisa Imagawa
Yuya Yamada
Yasuharu Tabara
Masakatsu Yamashita
Hideichi Makino
Tadashi Suehiro
P2860cites workGenome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetesQ24652324
Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk lociQ24658255
Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetesQ29417127
Can non-HLA Single Nucleotide Polymorphisms Help Stratify Risk in TrialNet Relatives at Risk for Type 1 Diabetes?Q30252380
Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY StudyQ30301275
Genetics of type 1 diabetes: what's next?Q30431554
Genetics and pathogenesis of type 1 diabetes: prospects for prevention and interventionQ33585528
Type 1 diabetes: new perspectives on disease pathogenesis and treatmentQ34321603
Prime role for an insulin epitope in the development of type 1 diabetes in NOD miceQ34345367
A genome-wide association study identifies KIAA0350 as a type 1 diabetes geneQ34651283
Association of type 1 diabetes with two Loci on 12q13 and 16p13 and the influence coexisting thyroid autoimmunity in JapaneseQ34862116
Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetesQ36501686
BACH2 represses effector programs to stabilize T(reg)-mediated immune homeostasis.Q37010319
Structure and function of active chromatin and DNase I hypersensitive sites.Q37866375
From Identification to Characterization of the Multiple Sclerosis Susceptibility Gene CLEC16A.Q38084534
Histone modifications for human epigenome analysisQ38112246
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection.Q38874311
T Cell Fates Zipped Up: How the Bach2 Basic Leucine Zipper Transcriptional Repressor Directs T Cell Differentiation and FunctionQ38920250
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.Q40055997
Incidence of childhood type 1 diabetes worldwide. Diabetes Mondiale (DiaMond) Project GroupQ43607374
Insulin administration may trigger type 1 diabetes in Japanese type 2 diabetes patients with type 1 diabetes high-risk HLA class II and the insulin gene VNTR genotypeQ44005752
HLA-class II and class I genotypes among Japanese children with Type 1A diabetes and their familiesQ46344393
Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetesQ46939565
Type 1 diabetes genome-wide association studies: not to be lost in translationQ49200841
Variants associated with autoimmune Type 1 diabetes in Japanese children: implications for age-specific effects of cis-regulatory haplotypes at 17q12-q21.Q50236470
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.Q52196097
IDDM2/insulin VNTR modifies risk conferred by IDDM1/HLA for development of Type 1 diabetes and associated autoimmunity.Q53798911
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for toleranceQ56701390
Expanded T cells from pancreatic lymph nodes of type 1 diabetic subjects recognize an insulin epitopeQ59060541
Insulin Antibodies in Insulin-Dependent Diabetics Before Insulin TreatmentQ70311233
Changes in the Islets of Langerhans in Cows Injected with Heterologous and Homologous InsulinQ71186933
Diabetes Mellitus in Rabbits Immunized with InsulinQ72781768
Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB StudyQ74607777
Insulin gene/IDDM2 locus in Japanese type 1 diabetes: contribution of class I alleles and influence of class I subdivision in susceptibility to type 1 diabetesQ79886788
Differential association of HLA with three subtypes of type 1 diabetes: fulminant, slowly progressive and acute-onsetQ84668994
Learning From Past Failures of Oral Insulin TrialsQ89206570
P433issue6
P304page(s)1447-1453
P577publication date2019-05-14
P1433published inJournal of Diabetes InvestigationQ28207066
P1476titleVariants in the BACH2 and CLEC16A gene might be associated with susceptibility to insulin-triggered type 1 diabetes
P478volume10

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cites work (P2860)
Q90745613Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM
Q89819628The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases

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